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Antibacterial compound-1

" in MedChemExpress (MCE) Product Catalog:

38

Inhibitors & Agonists

2

Biochemical Assay Reagents

1

Peptides

14

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0055
    Chlorogenic acid
    25+ Cited Publications

    3-O-Caffeoylquinic acid; Heriguard; NSC-407296

    		 HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species (ROS) Bacterial Influenza Virus Endogenous Metabolite Infection Cardiovascular Disease Inflammation/Immunology Cancer
    Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb. It is an orally active antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension compound .
    Chlorogenic acid
  • HY-N2922
    β-Amyrin

    		Amyloid-β NF-κB Neurological Disease Inflammation/Immunology
    β-Amyrin shows effectively counteract amyloid β (Aβ)-induced impairment of long-term potentiation (LTP). β-Amyrin is a promising candidate for Alzheimer's disease (AD) research. β-Amyrin exhibits anti-inflammatory effects, protective activity against pulmonary fibrosis, and notable antibacterial capabilities. β-Amyrin is an orally active natural triterpenoid compound .
    β-Amyrin
  • HY-Y0191
    α-Pyridone

    2-Pyridone

    		 Endogenous Metabolite Bacterial Infection
    α-Pyridone (2-Pyridone) is an antibacterial agent that plays an important role in the field of biochemical research. α-Pyridone can serve as a scaffold compound to synthesize a variety of active compounds .
    α-Pyridone
  • HY-W016153
    2-Bromo-4-methylphenol

    		Biochemical Assay Reagents Bacterial Fungal Infection
    2-Bromo-4-methylphenol is a versatile compound. 2-Bromo-4-methylphenol produces an iodine-like odor in reverse osmosis water and red wine matrices. 2-Bromo-4-methylphenol exhibits antibacterial properties and effectively inhibits the growth of bacteria and fungal. 2-Bromo-4-methylphenol is an important intermediate for a variety of organic compounds .
    2-Bromo-4-methylphenol
  • HY-N0055R
    Chlorogenic acid (Standard)

    3-O-Caffeoylquinic acid (Standard); Heriguard (Standard); NSC-407296 (Standard)

    		 Reference Standards HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species (ROS) Bacterial Influenza Virus Endogenous Metabolite Infection Inflammation/Immunology Cancer
    Chlorogenic acid (Standard) is the analytical standard of Chlorogenic acid. This product is intended for research and analytical applications. Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb. It is an orally active antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension compound .
    Chlorogenic acid (Standard)
  • HY-W041343
    4-Benzoylbenzoic acid

    Benzoylbenzoicacid

    		 Bacterial Antibiotic Photosensitizer Infection
    4-(Phenylcarbonyl)benzoic acid is a photooxidant. Upon light activation, 4-(Phenylcarbonyl)benzoic acid forms an electrophilic aromatic ketone that acts as an oxidant in organic synthesis or biological systems. 4-(Phenylcarbonyl)benzoic acid has been used in the study of amino acid oxidation, as well as the synthesis of photoactivated antibacterial and antiviral compounds 1 2 3.
    4-Benzoylbenzoic acid
  • HY-101819
    Antibacterial compound 1

    		Bacterial Infection
    Antibacterial compound 1 is a oxazolidinone extracted from patent WO1999037630A1 with antibacterial activities.
    Antibacterial compound 1
  • HY-126463
    LolCDE-IN-4

    		Bacterial Infection
    LolCDE-IN-4 (Compound 1) is exhibits antibacterial efficacy against gram negative bacteria Escherichia coli (MIC of 0.25-32 µg/ml) and Haemophilus influenzae, through inhibition LolCDE complex and disruption of lipoproteins release from the inner membrane .
    LolCDE-IN-4
  • HY-142075
    Antibacterial agent 134

    		Bacterial Infection
    Antibacterial agent 134 (compound 1) is an diketopiperazine alkaloid with antimicrobial activity. Antibacterial agent 134 is the major metabolite in the culture of Hymeniacidon perleve associated bioactive bacterium Pseudomonas sp. NJ6-3-1 .
    Antibacterial agent 134
  • HY-D0200
    Adipic acid dihydrazide

    Adipodihydrazide

    		 Bacterial Drug Intermediate Biochemical Assay Reagents Infection
    Adipic acid dihydrazide (Adipodihydrazide) is an antibacterial agent and crosslinking agent. Adipic acid dihydrazide can be used for the preparation of hydrogels. Adipic acid dihydrazide exhibits antibacterial activity against both Gram-positive and Gram-negative bacteria, such as Enterobacter aerogenes (MIC: 0.081 mg/mL) and Salmonella enterica (MIC: 0.99 mg/mL). Adipic acid dihydrazide is also an important intermediate that can be utilized in the synthesis of other active compounds .
    Adipic acid dihydrazide
  • HY-146637
    VIM-2-IN-1

    		Beta-lactamase Bacterial Infection
    VIM-2-IN-1 (compound 1dj) is a β-lactamase inhibitor with antibacterial activities. VIM-2-IN-1 has moderate IC50 values of 23 µM, 48 µM and 231 µM for Verona integron-encoded metallo-β-lactamase (VIM-2), German imipenemase-1 (GIM-1) and New Delhi metallo-β-lactamase (NDM-1), respectively .
    VIM-2-IN-1
  • HY-W007518
    4-Bromo-3-fluorobenzaldehyde

    		Drug Intermediate Infection
    4-Bromo-3-fluorobenzaldehyde is a drug intermediate that can be used for the synthesis of triaryl dimer antibacterial compounds .
    4-Bromo-3-fluorobenzaldehyde
  • HY-24547
    HpFabZ-IN-1

    		Phospholipase Infection
    HpFabZ-IN-1 (Compound 1) is an inhibitor of the key enzyme FabZ in the Helicobacter pylori fatty acid synthesis pathway, with its IC50 value being 39.8 µM. HpFabZ-IN-1 does not possess antibacterial activity .
    HpFabZ-IN-1
  • HY-138247
    β-Lactamase-IN-2

    EX-A4764; UUN51204

    		 Beta-lactamase Bacterial Antibiotic Infection
    β-Lactamase-IN-2 is a beta-lactamase inhibitor, extracted from patent WO 2019075084 A1, compound 1. β-Lactamase-IN-2 has anti-microbial and anti-bacterial effects .
    β-Lactamase-IN-2
  • HY-P11027
    Thiazoplanomicin

    		Bacterial Antibiotic Infection
    Thiazoplanomicin (Compound 1) is a thiazolyl peptide antibiotic. Thiazoplanomicin can be isolated from the leaf-litter actinomycete Actinoplanes sp. MM794L-181F6. Thiazoplanomicin has potent antimicrobial activities against gonococcal strains (especially drug-resistant strains) and Gram-positive bacterium with MICs of 31.2-125 and 0.5-15.6 ng/mL, respectively. Thiazoplanomicin has no antibacterial activity against E.coli. Thiazoplanomicin can be used for bacterial infections research .
    Thiazoplanomicin
  • HY-N16053
    Antibacterial agent 288

    		Bacterial Fungal Infection
    Antibacterial agent 288 (Compound 1) has antibacterial and antifungal activities. Antibacterial agent 288 can be isolated from Mangrove fungus (No. B60) from the South China Sea .
    Antibacterial agent 288
  • HY-113773
    KY-9

    		Bacterial Infection
    KY-9 is an antibacterial active compound .
    KY-9
  • HY-146199
    Antibacterial agent 108

    		Bacterial Infection
    Antibacterial agent 108 (Compound 1h) is a potent antibacterial agent with a MIC of both 3 μM against MRSA and antibiotic resistance strains .
    Antibacterial agent 108
  • HY-157141
    Antibacterial agent 163

    		Bacterial Infection
    Antibacterial agent 163 (compound 1), a hydroxyquinoline derivative, is a potent bacterial inhibitor. Antibacterial agent 163 inhibits methicillin-resistant Staphylococcus aureus (MRSA) .
    Antibacterial agent 163
  • HY-149353
    Antibacterial agent 145

    		Bacterial Infection
    Antibacterial agent 145 (compound 1b) is an antibacterial agent depending on bacterial iron uptake pathway. Antibacterial agent 145 disrupts cytoplasmic membrane integrity and inhibits cell metabolism but exhibits low cytotoxic effects to normal cells .
    Antibacterial agent 145
  • HY-147959
    Antibacterial agent 114

    		Bacterial Infection
    Antibacterial agent 114 (compound 1) is a potent antibacterial agent. Antibacterial agent 114 shows antibacterial activity against P.aeruginosa, B.subtilis, E.coli, E.faecalis, S.typhimuriumand, S.mutans, and S.aureus microorganisms, with MIC values of 625, 625, 625, 625, 625, 1250 and 1250 μM, respectively .
    Antibacterial agent 114
  • HY-163399
    Antibacterial agent 197

    		Bacterial Infection
    Antibacterial agent 197 (compound 1-deAA) is a termination inhibitor of non-classical anhydroglycosyl receptors and anhydrowall peptide-type peptidoglycan (PG) in bacterial TGase, with activity against Staphylococcus aureus. Antibacterial agent 197 synergizes with Vancomycin (HY-B0671) and is its antibacterial adjuvant .
    Antibacterial agent 197
  • HY-162839
    Cerastecin D

    		Bacterial Infection
    Cerastecin D (compound 1) is an antibacterial agent. Cerastecin D shows inhibition on Acinetobacter baumannii ATCC19606 with MITC95 values of 165 nM .
    Cerastecin D
  • HY-N12600
    Thiolopyrrolone A

    		Bacterial Infection
    Thiolopyrrolone A (compound 1) exhibits antibacterial activities against BCG, M. tuberculosis and S. aureus with minimum inhibitory concentrations (MIC) of 10, 10 and 100 μg/mL, respectively .
    Thiolopyrrolone A
  • HY-N16065
    Prenylterphenyllin

    		Bacterial Infection
    Prenylterphenyllin (Compound 1) is an antibacterial agent. Prenylterphenyllin can be isolated from marine-derived fungus Aspergillus candidus IF10. Prenylterphenyllin has cytotoxic activity against KB3-1 cells with an IC50 of 8.5 mg/mL. Prenylterphenyllin also has antibacterial activities against Xanthomonas oryzae and Erwinia amylovora with MICs of both 20 μg/mL .
    Prenylterphenyllin
  • HY-168511
    DNA Gyrase-IN-13

    		DNA/RNA Synthesis Bacterial Infection
    DNA Gyrase-IN-13 (compound 1b) is a DNA Gyrase inhibitor. DNA Gyrase-IN-13 has antibacterial activity. DNA Gyrase-IN-13 has an IC50 value of 1.81 μM for Staphylococcus aureus DNA gyrase .
    DNA Gyrase-IN-13
  • HY-118205
    SCH-538415

    		Bacterial Infection
    SCH-538415 is a novel acyl carrier protein synthase inhibitor isolated from an unknown bacterial microorganism. The structural elucidation of compound 1 was completed by analyzing spectral data including UV, MS and 2D-NMR spectra. Compound 1 showed inhibitory activity in the acyl carrier protein synthase (AcpS) test with an IC50 value of 4.19 μM and exhibited antibacterial activity against Staphylococcus aureus in the agar diffusion test.
    SCH-538415
  • HY-N2922R
    β-Amyrin (Standard)

    		Reference Standards Amyloid-β Neurological Disease
    β-Amyrin shows effectively counteract amyloid β (Aβ)-induced impairment of long-term potentiation (LTP). β-Amyrin is a promising candidate for Alzheimer's disease (AD) research. β-Amyrin exhibits anti-inflammatory effects, protective activity against pulmonary fibrosis, and notable antibacterial capabilities. β-Amyrin is an orally active natural triterpenoid compound .
    β-Amyrin (Standard)
  • HY-135535
    Sclerotioramine

    		Endogenous Metabolite Bacterial Fungal Infection
    Sclerotioramine (Compound 1), a red pigment, is an antioxidant compound. Sclerotioramine can be isolated from the endolichenic fungus Penicillium sp.-strain 1322P. Sclerotioramine has potent antibacterial activity with MICs of 3.125, 3.125 and 6.25 μg/mL for Bacillus subtilis, Bacillus megaterium and Shigella dysentery, respectively. Sclerotioramine also has significant antifungal activity against Pestalotiopsis theae, Cochliobolus miyabeanus and Exserohilum turcicum .
    Sclerotioramine
  • HY-Y0191R
    α-Pyridone (Standard)

    2-Pyridone (Standard)

    		 Reference Standards Endogenous Metabolite Bacterial Infection Metabolic Disease
    α-Pyridone (Standard) is the analytical standard of α-Pyridone. This product is intended for research and analytical applications. α-Pyridone (2-Pyridone) is an antibacterial agent. α-Pyridone can be synthesized via the 1,4-addition of 2-(phenylsulfinyl)acetamide to α,β-unsaturated ketones followed by cyclization and sulfoxide elimination. α-Pyridone can also be used to synthesize a wide range of heterocyclic compounds .
    α-Pyridone (Standard)
  • HY-168674
    Antibacterial agent 255

    		Bacterial Infection
    Antibacterial agent 255 (compound (±)-1) is a potent antibacterial agent. Antibacterial agent 255 is a potent and selective 4-diphosphocytidyl-2-C-methyl-D-erythritol (IspE) inhibitor with IC50 values of 13.0, 8.0, 20 µM for EclspE, KplspE, AblspE, respectively .
    Antibacterial agent 255
  • HY-N16443
    Sporminarin A

    		Endogenous Metabolite Fungal Bacterial Infection
    Sporminarin A (Compound 1), a polyketide, is a microbial secondary metabolite. Sporminarin A can be isolated from the Sporormiella minimoides. Sporminarin A has significant antifungal activity against Aspergillus flavus with an MIC50 of 25  μg/mL. Sporminarin A also has antibacterial activity against Staphylococcus aureus (ATCC 29213) and Candida albicans (ATCC 14053) .
    Sporminarin A
  • HY-N12229
    Penipurdin A

    		Endogenous Metabolite Bacterial Infection
    Penipurdin A (Compound 1), an anthraquinone, is a microbial secondary metabolite. Penipurdin A can be isolated from the soil fungus Penicillium purpurogenum SC0070. Penipurdin A has no significant cytotoxicity against cancer cells, such as A549, HepG2 and Hela cells. Penipurdin A has antibacterial activity against Enterococcus faecalis and Staphylococcus aureus .
    Penipurdin A
  • HY-N19224
    Pulvinic acid dilactone

    		Drug Derivative Bacterial Infection Neurological Disease Cancer
    Pulvinic acid dilactone (Compound 1) is a pulvinic acid derivative and Antibacterial agent. Pulvinic acid dilactone can be isolated from the lichen Candelaria concolor. Pulvinic acid dilactone moderately inhibits the growth of Bacillus subtilis. Pulvinic acid dilactone exerts positive inotropic effects. Pulvinic acid dilactone can be used in studies related to Bacillus subtilis infections and leukemia .
    Pulvinic acid dilactone
  • HY-180118
    Moxifloxacin prodrug-1 TFA

    		Bacterial Infection
    Moxifloxacin prodrug-1 TFA (Compound 1e) is a Moxifloxacin (HY-66011A) prodrug and antibacterial agent. Moxifloxacin prodrug-1 TFA exhibits comparable potent activity as Moxifloxacin against E. coli, S. aureus, K. pneumoniae, A. baumannii, and P. aeruginosa. Moxifloxacin prodrug-1 TFA inhibits Mtb .
    Moxifloxacin prodrug-1 TFA
  • HY-172390
    Florfenicol-propanoate-piperidin

    		Bacterial Infection
    Florfenicol-propanoate-piperidin (Compound 1) is the derivative of Florfenicol (HY-B1374). Florfenicol-propanoate-piperidin exhibits antibacterial activity, inhibits E. coli ATCC25922, Salmonella CICC110420, S. aureus ATCC29213, B. subtilis CMCC(B)63501, E. faecalis ATCC29212, S. suis CVCC606, and Haemophilus parasuis with MIC of 2-8 μM .
    Florfenicol-propanoate-piperidin
  • HY-122262
    NDM-1-IN-6

    		Beta-lactamase Bacterial Infection
    NDM-1-IN-6 (Compound 1) is a potent, selective and competitive New Delhi Metallo-β-lactamase-1 (NDM-1) inhibitor with a Ki of 0.72 μM. NDM-1-IN-6 has a synergistic antibacterial effect with the carbapenem antibiotic Meropenem (HY-13678). NDM-1-IN-6 is mainly used for research on NDM-1-mediated multidrug-resistant bacterial infections .
    NDM-1-IN-6
  • HY-Y0191S
    α-Pyridone-d5

    2-Pyridone-d5

    		 Isotope-Labeled Compounds Bacterial Endogenous Metabolite Infection Metabolic Disease
    α-Pyridone-d5 (2-Pyridone-d5) is the deuterium labeled α-Pyridone (HY-Y0191). α-Pyridone (2-Pyridone) is an antibacterial agent. α-Pyridone can be synthesized via the 1,4-addition of 2-(phenylsulfinyl)acetamide to α,β-unsaturated ketones followed by cyclization and sulfoxide elimination. α-Pyridone can also be used to synthesize a wide range of heterocyclic compounds .
    α-Pyridone-d5

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