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Cat. No.: HY-168511

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DNA Gyrase-IN-13

DNA Gyrase-IN-13 (compound 1b) is a DNA Gyrase inhibitor. DNA Gyrase-IN-13 has antibacterial activity. DNA Gyrase-IN-13 has an IC₅₀ value of 1.81 μM for Staphylococcus aureus DNA gyrase.

For research use only. We do not sell to patients.

CAS No.: 2247443-72-5
Formula: C₁₅H₂₁N₃O₃S
Molecular Weight:323.41

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

DNA Gyrase-IN-13 Chemical Structure

CAS No.: 2247443-72-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

DNA Gyrase-IN-13 (compound 1b) is a DNA Gyrase inhibitor. DNA Gyrase-IN-13 has antibacterial activity. DNA Gyrase-IN-13 has an IC₅₀ value of 1.81 μM for Staphylococcus aureus DNA gyrase^[1].

All DNA/RNA Synthesis Isoforms :

Chemical Information

CAS No. 2247443-72-5
Molecular Weight 323.41
Formula C₁₅H₂₁N₃O₃S
SMILES

CCCCCOC1=CC=C(C=C1)C(NNC(NC(C)=O)=S)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhang G,et al. Discovery of novel 1,4-dicarbonylthiosemicarbazides as DNA gyrase inhibitors for the treatment of MRSA infection. Eur J Med Chem. 2024 Sep 28;280:116905. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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DNA Gyrase-IN-13

All DNA/RNA Synthesis Isoforms