LolCDE-IN-4
Based on 1 Customer Validation
LolCDE-IN-4 (Compound 1) is exhibits antibacterial efficacy against gram negative bacteria Escherichia coli (MIC of 0.25-32 µg/ml) and Haemophilus influenzae, through inhibition LolCDE complex and disruption of lipoproteins release from the inner membrane.
For research use only. We do not sell to patients.
- Purity: 99.39%
- CAS No.: 1859918-13-0
- Formula: C20H21N3O2
- Molecular Weight:335.40
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 1859918-13-0
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Appearance Solid
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Molecular Weight 335.40
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Formula C20H21N3O2
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Color Off-white to light yellow
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SMILES
CC(C1=NC(C2=CC=NC=C2)=C(C3=CC=C(OCCO4)C4=C3)N1)(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (298.15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9815 mL | 14.9076 mL | 29.8151 mL | 74.5379 mL |
| 5 mM | 0.5963 mL | 2.9815 mL | 5.9630 mL | 14.9076 mL | |
| 10 mM | 0.2982 mL | 1.4908 mL | 2.9815 mL | 7.4538 mL | |
| 15 mM | 0.1988 mL | 0.9938 mL | 1.9877 mL | 4.9692 mL | |
| 20 mM | 0.1491 mL | 0.7454 mL | 1.4908 mL | 3.7269 mL | |
| 25 mM | 0.1193 mL | 0.5963 mL | 1.1926 mL | 2.9815 mL | |
| 30 mM | 0.0994 mL | 0.4969 mL | 0.9938 mL | 2.4846 mL | |
| 40 mM | 0.0745 mL | 0.3727 mL | 0.7454 mL | 1.8634 mL | |
| 50 mM | 0.0596 mL | 0.2982 mL | 0.5963 mL | 1.4908 mL | |
| 60 mM | 0.0497 mL | 0.2485 mL | 0.4969 mL | 1.2423 mL | |
| 80 mM | 0.0373 mL | 0.1863 mL | 0.3727 mL | 0.9317 mL | |
| 100 mM | 0.0298 mL | 0.1491 mL | 0.2982 mL | 0.7454 mL |
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