Adipic acid dihydrazide
Based on 1 Customer Validation
Adipic acid dihydrazide (Adipodihydrazide) is a crosslinking agent that reacts with aldehyde groups to form pH-sensitive hydrazone bonds. Adipic acid dihydrazide can be used to prepare oxi‑HA/ADH8 injectable hydrogels for nucleus pulposus regeneration and can also be used to construct Paclitaxel (HY-B0015)-loaded nanoformulations. Adipic acid dihydrazide can serve as an intermediate for organic synthesis-related research.
For research use only. We do not sell to patients.
- Purity : 99.92%
- CAS No.: 1071-93-8
- Formula: C6H14N4O2
- Molecular Weight:174.20
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Storage:
Store at room temperature, keep dry and cool.
In solvent -80°C, 1 year , -20°C, 6 months
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Adipic acid dihydrazide (ADH) is a homobifunctional crosslinker that reacts with aldehyde groups to form pH-sensitive hydrazone bonds, and can be used to construct oxidized hyaluronic acid-based injectable hydrogels and graphene quantum dot hybrid nanoformulations[1].
Adipic acid dihydrazide (ADH) can serve as a crosslinking component for the synthesis of oxi‑HA/ADH injectable hydrogels for nucleus pulposus regeneration[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1071-93-8
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Appearance Solid
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Molecular Weight 174.20
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Formula C6H14N4O2
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Color White to off-white
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SMILES
O=C(NN)CCCCC(NN)=O
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Synonyms
Adipodihydrazide
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature, keep dry and cool
In solvent -80°C 1 year -20°C 6 months
Solvent & Solubility
In Vitro:
DMSO : 10 mg/mL (57.41 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Purity & Documentation
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Data Sheet (275 KB)
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SDS (458 KB)
- English - EN (458 KB)
- Français - FR (458 KB)
- Deutsch - DE (458 KB)
- Norwegian - NO (458 KB)
- Español - ES (458 KB)
- Swedish - SV (458 KB)
- Italian - IT (458 KB)
- Korean - KR (458 KB)
- Portuguese - PT (458 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.7405 mL | 28.7026 mL | 57.4053 mL | 143.5132 mL |
| 5 mM | 1.1481 mL | 5.7405 mL | 11.4811 mL | 28.7026 mL | |
| 10 mM | 0.5741 mL | 2.8703 mL | 5.7405 mL | 14.3513 mL | |
| 15 mM | 0.3827 mL | 1.9135 mL | 3.8270 mL | 9.5675 mL | |
| 20 mM | 0.2870 mL | 1.4351 mL | 2.8703 mL | 7.1757 mL | |
| 25 mM | 0.2296 mL | 1.1481 mL | 2.2962 mL | 5.7405 mL | |
| 30 mM | 0.1914 mL | 0.9568 mL | 1.9135 mL | 4.7838 mL | |
| 40 mM | 0.1435 mL | 0.7176 mL | 1.4351 mL | 3.5878 mL | |
| 50 mM | 0.1148 mL | 0.5741 mL | 1.1481 mL | 2.8703 mL |
Adipic acid dihydrazide Related Classifications
HY-D0200 Related Classifications
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Keywords
- Adipic acid dihydrazide
- 1071-93-8
- Adipodihydrazide
- Drug Intermediate
- Biochemical Assay Reagents
- Drug Iintermediate
- bifunctional hydrazide cross-linker
- cortisol immunoassay
- graphene quantum dots
- horseradish peroxidase
- hyaluronic acid
- hydrazone bond
- nucleus pulposus regeneration
- oxidized hyaluronic acid hydrogel
- pH-triggered release
- rabbit NP cells
- Inhibitor
- inhibitor
- inhibit