1071-93-8
Chemical Structure
Adipic acid dihydrazide
Synonym(s): Adipodihydrazide
- CAS No.: 1071-93-8
- Formula:C6H14N4O2
- Molecular Weight:174.20
IUPAC Name: adipohydrazide
InChIKey: IBVAQQYNSHJXBV-UHFFFAOYSA-N
SMILES: O=C(NN)CCCCC(NN)=O
Biological Activity: Adipic acid dihydrazide (Adipodihydrazide) is a crosslinking agent that reacts with aldehyde groups to form pH-sensitive hydrazone bonds. Adipic acid dihydrazide can be used to prepare oxi‑HA/ADH8 injectable hydrogels for nucleus pulposus regeneration and can also be used to construct Paclitaxel (HY-B0015)-loaded nanoformulations. Adipic acid dihydrazide can serve as an intermediate for organic synthesis-related research[1][2][3].
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Adipic acid dihydrazide | 99.92% | Adipic acid dihydrazide (Adipodihydrazide) is a crosslinking agent that reacts with aldehyde groups to form pH-sensitive hydrazone bonds. Adipic acid dihydrazide can be used to prepare oxi‑HA/ADH8 injectable hydrogels for nucleus pulposus regeneration and can also be used to construct Paclitaxel (HY-B0015)-loaded nanoformulations. Adipic acid dihydrazide can serve as an intermediate for organic synthesis-related research. | ||||||||||||||||||||
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Adipic acid dihydrazide-d8 | 99% | Adipic acid dihydrazide-d8 (Adipodihydrazide-d8) is the deuterated-labeled Adipic acid dihydrazide (HY-D0200). Adipic acid dihydrazide (Adipodihydrazide) is a crosslinking agent that reacts with aldehyde groups to form pH-sensitive hydrazone bonds. Adipic acid dihydrazide can be used to prepare oxi‑HA/ADH8 injectable hydrogels for nucleus pulposus regeneration and can also be used to construct Paclitaxel (HY-B0015)-loaded nanoformulations. Adipic acid dihydrazide can serve as an intermediate for organic synthesis-related research. | ||||||||||||||||||||
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References
- [1]. Morani D O. Formulation and evaluation of hyaluronic acid and adipic acid dihydrazide modified graphene quantum dot-based nanotherapeutics for paclitaxel-targeted delivery in breast cancer. Futur J Pharm Sci, 2025, 11:7.
- [2]. Basu A, et al. Preparation of Enzyme Conjugate through Adipic Acid Dihydrazide as Linker and Its Use in Immunoassays. Clinical Chemistry, 2003, 49(8):1410-1412.
- [3]. Su WY, et al. Injectable oxidized hyaluronic acid/adipic acid dihydrazide hydrogel for nucleus pulposus regeneration. Acta biomaterialia. 2010 Aug;6(8):3044-55.
