Search Result

Results for "

Benzylisoquinoline

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Autophagy (5) Bacterial (2) Biochemical Assay Reagents (1) Cholinesterase (ChE) (3) Drug Derivative (1) Drug Intermediate (1) Endogenous Metabolite (3) Fungal (1) Histamine Receptor (1) Isotope-Labeled Compounds (3) nAChR (2) Potassium Channel (5) Reference Standards (2)
By Research Areas:	Cancer (5) Endocrinology (2) Infection (3) Inflammation/Immunology (4) Metabolic Disease (1) Neurological Disease (5)

Inhibitors & Agonists

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0221

Daurisoline 5 Publications Verification (R,R)-Daurisoline	Autophagy Potassium Channel	Cancer
Daurisoline is a bis-benzylisoquinoline alkaloid that can be isolated from Menispermum dauricum and Rhizoma Menispermi. Daurisoline exerts a blocking effect on hERG and has antiarrhythmic effects. Daurisoline is a potent autophagy blocker that can be used for the research of cancer .

HY-B1700A

Mivacurium dichloride	nAChR	Neurological Disease
Mivacurium dichloride is a benzylisoquinoline derivative and is a short-acting non-depolarizing neuromuscular blocking agent and skeletal muscle relaxant. Mivacurium dichloride couples with the nAChR to reduce or inhibit the depolarizing effect of acetylcholine on the terminal disc of the muscle cell .

HY-N2612

O-Methyldauricine 1 Publications Verification Daurisoline-d4; Dau-d4; (-)-O-Methyldauricine	Fungal Bacterial	Infection Neurological Disease
O-Methyldauricine ((-)-O-Methyldauricine) is an alkaloid with benzylisoquinoline group, which can be separated from P. ophthalmicus. O-Methyldauricine has antibacterial activity .

HY-N2037C

(S)-Higenamine hydrobromide 1 Publications Verification (S)-Norcoclaurine hydrobromide	Endogenous Metabolite	Others
(S)-Higenamine ((S)-Norcoclaurine) hydrobromide, a S-enantiomer of Higenamine, is the entry compound in benzylisoquinoline alkaloid biosynthesis. (S)-Higenamine hydrobromide is produced by the condensation of dopamine and 4-hydroxyphenylacetaldehyde (4-HPAA) by norcoclaurine synthase (NCS) .

HY-N7717

(-)-N-methylcoclaurine (–)-(1R)-N-methylcoclaurine	Drug Derivative	Metabolic Disease
(-)-N-methylcoclaurine ((-)-(1R)-N-methylcoclaurine) is a benzylisoquinoline alkaloid and melanogenesis inhibitor with an IC₅₀ of 6.5 μM that can be found in the flower buds of Nelumbo nucifera. (-)-N-methylcoclaurine inhibits theophylline-stimulated melanogenesis in melanoma cells. (-)-N-methylcoclaurine can be used for the research of skin hyperpigmentation disorders .

HY-N6894A

Pseudocoptisine chloride Isocoptisine chloride	Cholinesterase (ChE)	Inflammation/Immunology
Pseudocoptisine (Isocoptisine) chloride is a quaternary alkaloid with benzylisoquinoline skeleton, was isolated from Corydalis Tuber. Pseudocoptisine chloride inhibits acetylcholinesterase (AChE) activity with an IC₅₀ of 12.8 μM. Anti-inflammatory and anti-amnestic effects .

HY-N2037B

(S)-Higenamine (S)-Norcoclaurine	Endogenous Metabolite	Others
(S)-Higenamine ((S)-Norcoclaurine), a S-enantiomer of Higenamine, is the entry compound in benzylisoquinoline alkaloid biosynthesis. (S)-Higenamine is produced by the condensation of dopamine and 4-hydroxyphenylacetaldehyde (4-HPAA) by norcoclaurine synthase (NCS) .

HY-N6078

Thalrugosaminine	Bacterial	Infection
Thalrugosaminine is a benzylisoquinoline alkaloid isolated from the roots of Thalictrum minus. Thalrugosaminine shows good antibacterial activity with MIC values of 64-128 µg/ml .

HY-B1700AR

Mivacurium dichloride (Standard)	Reference Standards nAChR	Neurological Disease
Mivacurium (dichloride) (Standard) is the analytical standard of Mivacurium (dichloride). This product is intended for research and analytical applications. Mivacurium dichloride is a benzylisoquinoline derivative and is a short-acting non-depolarizing neuromuscular blocking agent and skeletal muscle relaxant. Mivacurium dichloride couples with the nAChR to reduce or inhibit the depolarizing effect of acetylcholine on the terminal disc of the muscle cell .

HY-N12845

Pseudolaroside A	Others	Endocrinology
Pseudolaroside A is a benzylisoquinoline glycoside that can be isolated from Pseudolarix kaempferi .

HY-N12844

Pseudolaroside B	Others	Endocrinology
Pseudolaroside B is a benzylisoquinoline glycoside that can be isolated from Pseudolarix kaempferi .

HY-W705415A

N-Methylcoclaurine	Drug Intermediate	Infection
(S)-N-methylcoclaurine is a substrate of CyNMCH. (S)-N-methylcoclaurine serves as an important branch point intermediate in benzylisoquinoline alkaloid biosynthesis.

HY-N6894

Pseudocoptisine acetate Isocoptisine acetate	Cholinesterase (ChE)	Inflammation/Immunology
Pseudocoptisine (Isocoptisine) acetate is a quaternary alkaloid with benzylisoquinoline skeleton, was isolated from Corydalis Tuber. Pseudocoptisine acetate inhibits acetylcholinesterase (AChE) activity with an IC₅₀ of 12.8 μM. Anti-inflammatory and anti-amnestic effects .

HY-N12027

AChE/BChE-IN-14	Cholinesterase (ChE)	Neurological Disease
AChE/BChE-IN-14 (compound 13) is a benzylisoquinoline alkaloid isolated from the roots of Fissistigma polyanthum. AChE/BChE-IN-14 exhibits AChE and BChE inhibitions with antioxidant activities. AChE/BChE-IN-14 can be used for Alzheimer’s disease research .

HY-N0221R

Daurisoline (Standard) (R,R)-Daurisoline (Standard)	Autophagy Potassium Channel Reference Standards	Cancer
Daurisoline (Standard) is the analytical standard of Daurisoline. This product is intended for research and analytical applications. Daurisoline is a bis-benzylisoquinoline alkaloid that can be isolated from Menispermum dauricum and Rhizoma Menispermi. Daurisoline exerts a blocking effect on hERG and has antiarrhythmic effects. Daurisoline is a potent autophagy blocker that can be used for the research of cancer .

HY-N0221S

Daurisoline-d2 (R,R)-Daurisoline-d₂	Isotope-Labeled Compounds Potassium Channel Autophagy	Cancer
Daurisoline-d₂ is the deuterium labeled Daurisoline (HY-N0221). Daurisoline is a bis-benzylisoquinoline alkaloid that can be isolated from Menispermum dauricum and Rhizoma Menispermi. Daurisoline exerts a blocking effect on hERG and has antiarrhythmic effects. Daurisoline is a potent autophagy blocker that can be used for the research of cancer .

HY-N0221S2

Daurisoline-d11 (R,R)-Daurisoline-d₁₁	Isotope-Labeled Compounds Potassium Channel Autophagy	Cancer
Daurisoline-d₁₁ is the deuterium labeled Daurisoline (HY-N0221). Daurisoline is a bis-benzylisoquinoline alkaloid that can be isolated from Menispermum dauricum and Rhizoma Menispermi. Daurisoline exerts a blocking effect on hERG and has antiarrhythmic effects. Daurisoline is a potent autophagy blocker that can be used for the research of cancer .

HY-N0221S1

Daurisoline-d5 (R,R)-Daurisoline-d₅	Isotope-Labeled Compounds Potassium Channel Autophagy	Cancer
Daurisoline-d₅ is the deuterium labeled Daurisoline (HY-N0221). Daurisoline is a bis-benzylisoquinoline alkaloid that can be isolated from Menispermum dauricum and Rhizoma Menispermi. Daurisoline exerts a blocking effect on hERG and has antiarrhythmic effects. Daurisoline is a potent autophagy blocker that can be used for the research of cancer .

HY-118392

Papaveraldine Xanthaline	Histamine Receptor	Inflammation/Immunology
Papaveraldine (Xanthaline) is a benzylisoquinoline alkaloid that shows antispasmodic and protective activity against histamine-induced bronchospasm in rats. Papaveraldine is an active ingredient of a hair tonic preparation that promotes melanin formation for grey hair .

HY-135945

Dihydrocoptisine	Biochemical Assay Reagents	Inflammation/Immunology
Dihydrocoptisine is a benzylisoquinoline alkaloid that can be isolated from the methanolic extract of the whole plant of Argemone mexicana L. Dihydrocoptisine can activate XBP1 transcription activity. Dihydrocoptisine can be studied in research on anti-ulcertative colitis .

HY-N13111

Neoliensinine	Others	Others
Neoliensinine is a benzylisoquinoline that effectively inhibits KCl (124 mM)-induced contraction of isolated mesenteric vascular smooth muscle (MVSM) with an IC₅₀ value of 2.407 μM. Neoliensinine can be isolated from the embryo of Nelumbo nucifera Gaertn., a traditional Chinese medicine.

HY-W746289

Narcotoline	Endogenous Metabolite	Neurological Disease
Narcotoline, a phenylpyridine isoquinoline alkaloid, is a by-product in the biosynthetic pathway of Noscapine (HY-13716). Narcotoline can be used to study the metabolic regulatory agents of Noscapine .

Cat. No.	Product Name	Target	Research Area

HY-P3983

[Cys(Bzl)84] CD (81-92)	Peptides	Others
[Cys(Bzl)84] CD (81-92) is an acidic peptide. [Cys(Bzl)84] CD (81-92) can be sequencing by negative ion postsource decay (PSD) spectra .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0221

Daurisoline 5 Publications Verification (R,R)-Daurisoline	Alkaloids other families Classification of Application Fields Phenols Polyphenols Plants Isoquinoline Alkaloids Disease Research Fields Source Classification Cancer	Autophagy Potassium Channel
Daurisoline is a bis-benzylisoquinoline alkaloid that can be isolated from Menispermum dauricum and Rhizoma Menispermi. Daurisoline exerts a blocking effect on hERG and has antiarrhythmic effects. Daurisoline is a potent autophagy blocker that can be used for the research of cancer .

HY-N2612

O-Methyldauricine 1 Publications Verification Daurisoline-d4; Dau-d4; (-)-O-Methyldauricine	Alkaloids Piperidine Alkaloids Plants Menispermaceae Hypserpa nitida Miers Source Classification	Fungal Bacterial
O-Methyldauricine ((-)-O-Methyldauricine) is an alkaloid with benzylisoquinoline group, which can be separated from P. ophthalmicus. O-Methyldauricine has antibacterial activity .

HY-N2037C

(S)-Higenamine hydrobromide 1 Publications Verification (S)-Norcoclaurine hydrobromide	Alkaloids Classification of Application Fields Other Diseases Phenols Polyphenols Endogenous metabolite Isoquinoline Alkaloids Disease Research Fields Source Classification	Endogenous Metabolite
(S)-Higenamine ((S)-Norcoclaurine) hydrobromide, a S-enantiomer of Higenamine, is the entry compound in benzylisoquinoline alkaloid biosynthesis. (S)-Higenamine hydrobromide is produced by the condensation of dopamine and 4-hydroxyphenylacetaldehyde (4-HPAA) by norcoclaurine synthase (NCS) .

HY-N7717

(-)-N-methylcoclaurine (–)-(1R)-N-methylcoclaurine	Alkaloids Structural Classification Classification of Application Fields Phenols Polyphenols Metabolic Disease Nelumbo nucifera Gaertn. Plants Isoquinoline Alkaloids Nymphaeaceae Disease Research Fields Source Classification	Drug Derivative
(-)-N-methylcoclaurine ((-)-(1R)-N-methylcoclaurine) is a benzylisoquinoline alkaloid and melanogenesis inhibitor with an IC₅₀ of 6.5 μM that can be found in the flower buds of Nelumbo nucifera. (-)-N-methylcoclaurine inhibits theophylline-stimulated melanogenesis in melanoma cells. (-)-N-methylcoclaurine can be used for the research of skin hyperpigmentation disorders .

HY-N6894A

Pseudocoptisine chloride Isocoptisine chloride	Alkaloids Piperidine Alkaloids Classification of Application Fields Plants Isoquinoline Alkaloids Disease Research Fields Inflammation/Immunology Papaveraceae Source Classification Corydalis turtschaninovii Bess.	Cholinesterase (ChE)
Pseudocoptisine (Isocoptisine) chloride is a quaternary alkaloid with benzylisoquinoline skeleton, was isolated from Corydalis Tuber. Pseudocoptisine chloride inhibits acetylcholinesterase (AChE) activity with an IC₅₀ of 12.8 μM. Anti-inflammatory and anti-amnestic effects .

HY-N2037B

(S)-Higenamine (S)-Norcoclaurine	Alkaloids Classification of Application Fields Other Diseases Phenols Polyphenols Endogenous metabolite Isoquinoline Alkaloids Disease Research Fields Source Classification	Endogenous Metabolite
(S)-Higenamine ((S)-Norcoclaurine), a S-enantiomer of Higenamine, is the entry compound in benzylisoquinoline alkaloid biosynthesis. (S)-Higenamine is produced by the condensation of dopamine and 4-hydroxyphenylacetaldehyde (4-HPAA) by norcoclaurine synthase (NCS) .

HY-N6078

Thalrugosaminine	Infection Alkaloids Thalictrum minus Linn. Classification of Application Fields Ranunculaceae Plants Disease Research Fields Alkaloid Dimers Source Classification	Bacterial
Thalrugosaminine is a benzylisoquinoline alkaloid isolated from the roots of Thalictrum minus. Thalrugosaminine shows good antibacterial activity with MIC values of 64-128 µg/ml .

HY-N12845

Pseudolaroside A	Pinaceae Ketones, Aldehydes, Acids Pseudolarix amabilis (J. Nelson) Rehder Plants Source Classification	Others
Pseudolaroside A is a benzylisoquinoline glycoside that can be isolated from Pseudolarix kaempferi .

HY-N12844

Pseudolaroside B	Pinaceae Ketones, Aldehydes, Acids Pseudolarix amabilis (J. Nelson) Rehder Plants Source Classification	Others
Pseudolaroside B is a benzylisoquinoline glycoside that can be isolated from Pseudolarix kaempferi .

HY-N6894

Pseudocoptisine acetate Isocoptisine acetate	Alkaloids Phellodendron amurense Rupr. Classification of Application Fields Rutaceae Plants Isoquinoline Alkaloids Disease Research Fields Inflammation/Immunology Source Classification	Cholinesterase (ChE)
Pseudocoptisine (Isocoptisine) acetate is a quaternary alkaloid with benzylisoquinoline skeleton, was isolated from Corydalis Tuber. Pseudocoptisine acetate inhibits acetylcholinesterase (AChE) activity with an IC₅₀ of 12.8 μM. Anti-inflammatory and anti-amnestic effects .

HY-N12027

AChE/BChE-IN-14	Alkaloids Fissistigma polyanthum (Hook. f. et Thoms.) Merr. Plants Annonaceae Isoquinoline Alkaloids Source Classification	Cholinesterase (ChE)
AChE/BChE-IN-14 (compound 13) is a benzylisoquinoline alkaloid isolated from the roots of Fissistigma polyanthum. AChE/BChE-IN-14 exhibits AChE and BChE inhibitions with antioxidant activities. AChE/BChE-IN-14 can be used for Alzheimer’s disease research .

HY-N0221R

Daurisoline (Standard) (R,R)-Daurisoline (Standard)	Alkaloids Structural Classification other families Phenols Polyphenols Plants Isoquinoline Alkaloids Source Classification	Autophagy Potassium Channel Reference Standards
Daurisoline (Standard) is the analytical standard of Daurisoline. This product is intended for research and analytical applications. Daurisoline is a bis-benzylisoquinoline alkaloid that can be isolated from Menispermum dauricum and Rhizoma Menispermi. Daurisoline exerts a blocking effect on hERG and has antiarrhythmic effects. Daurisoline is a potent autophagy blocker that can be used for the research of cancer .

HY-N13111

Neoliensinine	Monophenols Phenols Nelumbo nucifera Gaertn. Plants Nymphaeaceae Source Classification	Others
Neoliensinine is a benzylisoquinoline that effectively inhibits KCl (124 mM)-induced contraction of isolated mesenteric vascular smooth muscle (MVSM) with an IC₅₀ value of 2.407 μM. Neoliensinine can be isolated from the embryo of Nelumbo nucifera Gaertn., a traditional Chinese medicine.

HY-W746289

Narcotoline	Structural Classification Phenols Papaver somniferum Linn. Plants Papaveraceae Source Classification	Endogenous Metabolite
Narcotoline, a phenylpyridine isoquinoline alkaloid, is a by-product in the biosynthetic pathway of Noscapine (HY-13716). Narcotoline can be used to study the metabolic regulatory agents of Noscapine .

Cat. No.	Product Name	Chemical Structure

HY-N0221S

Daurisoline-d2
Daurisoline-d₂ is the deuterium labeled Daurisoline (HY-N0221). Daurisoline is a bis-benzylisoquinoline alkaloid that can be isolated from Menispermum dauricum and Rhizoma Menispermi. Daurisoline exerts a blocking effect on hERG and has antiarrhythmic effects. Daurisoline is a potent autophagy blocker that can be used for the research of cancer .

HY-N0221S2

Daurisoline-d11
Daurisoline-d₁₁ is the deuterium labeled Daurisoline (HY-N0221). Daurisoline is a bis-benzylisoquinoline alkaloid that can be isolated from Menispermum dauricum and Rhizoma Menispermi. Daurisoline exerts a blocking effect on hERG and has antiarrhythmic effects. Daurisoline is a potent autophagy blocker that can be used for the research of cancer .

HY-N0221S1

Daurisoline-d5
Daurisoline-d₅ is the deuterium labeled Daurisoline (HY-N0221). Daurisoline is a bis-benzylisoquinoline alkaloid that can be isolated from Menispermum dauricum and Rhizoma Menispermi. Daurisoline exerts a blocking effect on hERG and has antiarrhythmic effects. Daurisoline is a potent autophagy blocker that can be used for the research of cancer .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Benzylisoquinoline

Inhibitors & Agonists

Peptides

NaturalProducts

Isotope-Labeled Compounds

Natural
Products