1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. (S)-Higenamine hydrobromide

(S)-Higenamine hydrobromide  (Synonyms: (S)-Norcoclaurine hydrobromide)

Cat. No.: HY-N2037C
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(S)-Higenamine ((S)-Norcoclaurine) hydrobromide, a S-enantiomer of Higenamine, is the entry compound in benzylisoquinoline alkaloid biosynthesis. (S)-Higenamine hydrobromide is produced by the condensation of dopamine and 4-hydroxyphenylacetaldehyde (4-HPAA) by norcoclaurine synthase (NCS).

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(S)-Higenamine hydrobromide Chemical Structure

(S)-Higenamine hydrobromide Chemical Structure

CAS No. : 105990-27-0

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Based on 1 publication(s) in Google Scholar

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Description

(S)-Higenamine ((S)-Norcoclaurine) hydrobromide, a S-enantiomer of Higenamine, is the entry compound in benzylisoquinoline alkaloid biosynthesis. (S)-Higenamine hydrobromide is produced by the condensation of dopamine and 4-hydroxyphenylacetaldehyde (4-HPAA) by norcoclaurine synthase (NCS)[1].

In Vitro

The biosynthetic pathway leading to benzylisoquinoline alkaloids originates from the enzyme-catalyzed condensation of dopamine and 4-hydrophenylacetaldehyde to yield (S)-norcoclaurine. Both substrates are secondary metabolites derived from the decarboxylation/hydroxylation/deamination of tyrosine[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

352.22

Formula

C16H18BrNO3

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC1=CC2=C([C@H](CC3=CC=C(O)C=C3)NCC2)C=C1O.[H]Br

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation
References
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(S)-Higenamine hydrobromide Related Classifications

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(S)-Higenamine hydrobromide
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