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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
33 Results for "
CO release
" in MedChemExpress (MCE) Product Catalog:
Products (33)
33 Results for "CO release" in MCE Product Catalog:
12
12 Cited Publications
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CORM-401 is an oxidant-sensitive CO-releasing molecule. CORM-401 induces NO increase in the regulation of endothelial calcium signalling. CORM-401 reduces TNF-α/CHX and H2O2-induced ROS production. CORM-401 uncouples mitochondrial respiration and inhibits glycolysis .
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Tricarbonyldichlororuthenium(II) dimer (CORM-2) is a CO-releasing molecule. Tricarbonyldichlororuthenium(II) dimer exhibits anti-inflammatory, antioxidant, and gastric mucosa-protective activities. Additionally, Tricarbonyldichlororuthenium(II) dimer has CO-independent functional effects on multiple potassium channels .
Cat. No.: HY-P0084
CAS No.: 38916-34-6
Synonyms: SRIF-14; Somatostatin-14
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Cat. No.: HY-D1244
CAS No.: 1043865-37-7
Cat. No.: HY-W011426
CAS No.: 142-91-6
Synonyms: Propan-2-yl hexadecanoate
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Cat. No.: HY-W782399
CAS No.: 17363-08-5
Synonyms: Sodium boranocarbonate
Cat. No.: HY-D0142
CAS No.: 59572-10-0
Cat. No.: HY-Y0850U5
CAS No.: 9002-89-5
Synonyms: Polyvinyl alCOhol (Mw 27000, 98-99% hydrolyzed, ~600 polymerization); Poly(Ethenol) (Mw 27000, 98-99% hydrolyzed, ~600 polymerization)
Cat. No.: HY-144368
CAS No.: 1972616-04-8
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CO delivery molecule 1 (compound 4) localizes to the endoplasmic reticulum, mitochondria, and lysosomes. Subcellular localization of CO delivery molecule 1 results in CO-induced toxicity effects. Anti-inflammatory effects of CO delivery molecule 1, as measured by TNF-α suppression, occur at the nanomolar level in the absence of CO release, and are enhanced with visible-light-induced CO release .
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photoCORM-2 (compound 3) is a single carbon monoxide releasing molecule (CORM). photoCORM-2 exhibits good cellular uptake and real-time monitoring ability of CO uncaging by a color change approach. photoCORM-2 has anti-tumor activity .
Cat. No.: HY-W250721E
CAS No.: 9007-20-9
Synonyms: Carboxy polymethylene (COpolymer)
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Carbomer copolymer can be used as an excipient, such as Bioadhesives, emulsifiers, release modifiers, suspending agents, tablet binders, viscosity enhancers, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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Ethyl acrylate-methyl methacrylate copolymer can be used as an excipient, such as sustained-release coating materials, matrix sustained-release tablet binders and retarders. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
Cat. No.: HY-P0084A
CAS No.: 54472-66-1
Synonyms: SRIF-14 acetate; Somatostatin-14 acetate
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Cat. No.: HY-W018475
CAS No.: 144034-80-0
Synonyms: MK 462 free base
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Rizatriptan (MK 462 free base) is an orally active 5-HT1B/5-HT1D receptor agonist, with BBB permeability. Rizatriptan exerts significant anti-migraine effects by constricting intracranial and extracranial blood vessels and inhibiting neuropeptide release. Rizatriptan exhibits species- and tissue-specific metabolic characteristics; for example, it undergoes oxidative deamination mainly by MAO-A in the liver of brown rats, so co-administration with MAO-A inhibitors is prohibited. Rizatriptan may also exacerbate nitroglycerin-induced cutaneous allodynia, prolong the duration of central sensitization, and increase anxiety-like behavior and active drug-seeking behavior in mice. Rizatriptan has been widely used in studies related to migraine and medication-overuse headache .
Cat. No.: HY-143617
CAS No.: 2892235-56-0
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photoCORM-1 (compound 8) is a combinatorial carbon monoxide releasing molecule (CORM). photoCORM-1 exhibits good cellular uptake and real-time monitoring ability of CO uncaging by a color change approach. photoCORM-1 has anti-tumor antivity .
Cat. No.: HY-P2229
CAS No.: 119719-11-8
Synonyms: SDZ CO 611
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Cat. No.: HY-136820S1
Cat. No.: HY-W011426R
CAS No.: 142-91-6
Synonyms: Propan-2-yl hexadecanoate (Standard)
Cat. No.: HY-W012618R
CAS No.: 93-54-9
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Isopropyl palmitate (Standard) is the analytical standard of Isopropyl palmitate. This product is intended for research and analytical applications. Isopropyl palmitate is an fatty acid ester. Isopropyl palmitate can be used for design and characterization of bioactive bilayer films. The bilayer membrane not only has the ability to scavenge free radicals and inhibit lipid peroxidation, but also can inhibit the growth of known foodborne pathogens. Isopropyl palmitate can be used as an excipient, such as lubricant, oily carrier, solvent, controlled-release transdermal film. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
Cat. No.: HY-W075620
CAS No.: 1341134-09-5
NH2-MIL-88B (Fe) is a metal-organic framework (MOF) with coordinatively unsaturated iron sites and carbon monoxide-releasing activity. NH2-MIL-88B (Fe) binds with carbon monoxide to form Fe 2+-CO and Fe 3+-CO adducts, and releases the bound carbon monoxide under physiological conditions, serving as a carrier and delivery vehicle for gaseous transmitters .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
