Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium

Name: Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium
Brand: MedChemExpress
SKU: HY-D0142
Rating: 4.5 (0 reviews)

Art. -Nr.: HY-D0142 Reinheit: 99.0%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium is a fluorescent dye and pH indicator, also as a ligand of multifunctional metal-organic framework. Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium has been used to detect CO₂ release. Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium acts as a water-soluble fluorescent dye for fluorescence quenching assays monitoring gramicidin ion-channel activity.

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Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium Chemische Struktur

CAS. Nr. : 59572-10-0

Größe	Verfügbarkeit	Menge
5 g	Auf Lager	Estimated Time of Arrival: December 31
10 g	Auf Lager	Estimated Time of Arrival: December 31
25 g	Auf Lager	Estimated Time of Arrival: December 31
50 g	Auf Lager	Estimated Time of Arrival: December 31
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Spezialitätsempfehlungen

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•Related Proteins:

Biologische Aktivität
Reinheit & Dokumentation
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Beschreibung

In Vitro

Pyrene-1,3,6,8-tetrasulfonic acid (4.16 mM; 90-100 min) enables detection of preserved gramicidin ion-channel activity in sol-gel immobilized EyPC LUVs, as shown by a K_SV of 1.03 that matches the free vesicle system^[2].
Pyrene-1,3,6,8-tetrasulfonic acid (4.16 mM; 90-100 min) enables detection of preserved gramicidin ion-channel activity in sol-gel immobilized EyPG LUVs, as shown by a K_SV of 1.23^[2].
Pyrene-1,3,6,8-tetrasulfonic acid exhibits consistent long fluorescence mean-lifetimes across acidic, neutral, and basic aqueous solutions, with measured values of 13.0 ns (pH 4), 12.4 ns (pH ~7), and 12.4 ns (pH 10)^[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molekulargewicht

610.43

Formel

C₁₆H₆Na₄O₁₂S₄

CAS. Nr.

59572-10-0

Appearance

Solid

Color

Light yellow to yellow

SMILES

[Na].O=S(=O)(O)C1=CC(=C2C=CC=3C=4C(=CC=C1C24)C(=CC3S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Lösungsmittel & Löslichkeit

In Vitro:

H₂O : 100 mg/mL (163.82 mM; Need ultrasonic)

DMSO : 2 mg/mL (3.28 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.6382 mL	8.1909 mL	16.3819 mL
5 mM	0.3276 mL	1.6382 mL	3.2764 mL
10 mM	0.1638 mL	0.8191 mL	1.6382 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molaritätsrechner
Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Reinheit & Dokumentation

Purity: 99.0%

Select Batch:

Data Sheet (281 KB) SDS (393 KB)

COA (259 KB)

Handling Instructions (2659 KB)

Verweise

[1]. Wang XB, et al. Probing the electronic stability of multiply charged anions: sulfonated pyrene tri- and tetraanions. J Am Chem Soc. 2009;131(28):9836-9842.

[2]. Esquembre R, et al. Biophysical and functional characterization of an ion channel peptide confined in a sol-gel matrix. J Phys Chem B. 2009;113(21):7534-7540.

[3]. Zhang, J. Rational designed of graphene dispersant. 30 Nov 2016

[4]. Boni L, et al. Fluorescence Mean-Lifetimes of a Series of Small and Bright Fluorescent Dyes. Luminescence. 2026;41(1):e70392.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / H₂O	1 mM	1.6382 mL	8.1909 mL	16.3819 mL	40.9547 mL
H₂O	5 mM	0.3276 mL	1.6382 mL	3.2764 mL	8.1909 mL
	10 mM	0.1638 mL	0.8191 mL	1.6382 mL	4.0955 mL
	15 mM	0.1092 mL	0.5461 mL	1.0921 mL	2.7303 mL
	20 mM	0.0819 mL	0.4095 mL	0.8191 mL	2.0477 mL
	25 mM	0.0655 mL	0.3276 mL	0.6553 mL	1.6382 mL
	30 mM	0.0546 mL	0.2730 mL	0.5461 mL	1.3652 mL
	40 mM	0.0410 mL	0.2048 mL	0.4095 mL	1.0239 mL
	50 mM	0.0328 mL	0.1638 mL	0.3276 mL	0.8191 mL
	60 mM	0.0273 mL	0.1365 mL	0.2730 mL	0.6826 mL
	80 mM	0.0205 mL	0.1024 mL	0.2048 mL	0.5119 mL
	100 mM	0.0164 mL	0.0819 mL	0.1638 mL	0.4095 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.