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Cat. No.: HY-179628

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STING agonist-49-CO-C2-mal-Cys

STING agonist-49-CO-C2-mal-Cys (compound 2), the derivative of STING agonist-49-CO-C2-mal (HY-179627), is the product of ADC catabolism and payload release, exhibits antitumor activity in vivo.

For research use only. We do not sell to patients.

CAS No.: 2803608-05-9
Formula: C₄₉H₅₉N₁₅O₁₁S
Molecular Weight:1066.15

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

STING agonist-49-CO-C2-mal-Cys Chemical Structure

CAS No.: 2803608-05-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

STING agonist-49-CO-C2-mal-Cys (compound 2), the derivative of STING agonist-49-CO-C2-mal (HY-179627), is the product of ADC catabolism and payload release, exhibits antitumor activity in vivo^[1].

Chemical Information

CAS No. 2803608-05-9
Molecular Weight 1066.15
Formula C₄₉H₅₉N₁₅O₁₁S
SMILES

O=C(C1=CC(C)=NN1CC)NC2=NC3=CC(C(N)=O)=CC(OC)=C3N2C/C=C/CN4C(NC(C5=CC(C)=NN5CC)=O)=NC6=C4C(OCCCN(C)C(CCN7C(CC(SC[C@@H](C(O)=O)N)C7=O)=O)=O)=CC(C(N)=O)=C6
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Gruber DR, et al. Targeted delivery of a potent STING agonist payload via an antibody drug conjugate drives robust antitumor activity in preclinical models. Mol Cancer Ther. 2025 Oct 29. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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