CORM-A1
Based on 1 Customer Validation
CORM-A1 (Sodium boranocarbonate) is a water-soluble carbon monoxide (CO) releasing molecule that facilitates the investigation of CO's impact on cellular systems. As CO is generated from heme degradation by the enzyme heme oxygenase, it serves as a crucial gaseous signaling mediator in mammalian cells. CORM-A1 not only exhibits anti-oxidant and anti-inflammatory properties but also regulates CO release in a manner dependent on pH and temperature, promoting mild vasorelaxation and hypotension. Furthermore, CORM-A1 has been shown to provide cytoprotection in primary cultures of astrocytes under oxidative stress while also enhancing autophagy due to its boron-containing composition.
For research use only. We do not sell to patients.
- Purity: 95.0%
- CAS No.: 17363-08-5
- Formula: CH3BNa2O2
- Molecular Weight:103.82
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Chemical Information
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CAS No. 17363-08-5
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Appearance Solid
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Molecular Weight 103.82
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Formula CH3BNa2O2
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Color White to off-white
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SMILES
[Na][Na].O=C=O.B
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Synonyms
Sodium boranocarbonate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : ≥ 50 mg/mL (481.60 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (243 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 9.6321 mL | 48.1603 mL | 96.3206 mL | 240.8014 mL |
| 5 mM | 1.9264 mL | 9.6321 mL | 19.2641 mL | 48.1603 mL | |
| 10 mM | 0.9632 mL | 4.8160 mL | 9.6321 mL | 24.0801 mL | |
| 15 mM | 0.6421 mL | 3.2107 mL | 6.4214 mL | 16.0534 mL | |
| 20 mM | 0.4816 mL | 2.4080 mL | 4.8160 mL | 12.0401 mL | |
| 25 mM | 0.3853 mL | 1.9264 mL | 3.8528 mL | 9.6321 mL | |
| 30 mM | 0.3211 mL | 1.6053 mL | 3.2107 mL | 8.0267 mL | |
| 40 mM | 0.2408 mL | 1.2040 mL | 2.4080 mL | 6.0200 mL | |
| 50 mM | 0.1926 mL | 0.9632 mL | 1.9264 mL | 4.8160 mL | |
| 60 mM | 0.1605 mL | 0.8027 mL | 1.6053 mL | 4.0134 mL | |
| 80 mM | 0.1204 mL | 0.6020 mL | 1.2040 mL | 3.0100 mL | |
| 100 mM | 0.0963 mL | 0.4816 mL | 0.9632 mL | 2.4080 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.