Isopropyl palmitate
Based on 1 Customer Validation
Isopropyl palmitate is an fatty acid ester. Isopropyl palmitate can be used for design and characterization of bioactive bilayer films. The bilayer membrane not only has the ability to scavenge free radicals and inhibit lipid peroxidation, but also can inhibit the growth of known foodborne pathogens. Isopropyl palmitate can be used as an excipient, such as lubricant, oily carrier, solvent, controlled-release transdermal film. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs.
For research use only. We do not sell to patients.
- Purity: 99.23%
- CAS No.: 142-91-6
- Formula: C19H38O2
- Molecular Weight:298.51
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Isopropyl palmitate can be used as the oil phase in the microemulsion system for cosmetics and drug delivery use. Isopropyl palmitate is a skin penetration enhancer that promotes the drug permeability through the skin barrier and improves the efficacy of transdermal drug delivery systems[3][4].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 142-91-6
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Appearance <11°C Solid,>13°C Liquid
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Molecular Weight 298.51
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Formula C19H38O2
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Color Colorless to white
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SMILES
CCCCCCCCCCCCCCCC(OC(C)C)=O
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Synonyms
Propan-2-yl hexadecanoate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 10 mg/mL (33.50 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Luís Â, et al. Design and Characterization of Bioactive Bilayer Films: Release Kinetics of Isopropyl Palmitate. Antibiotics (Basel). 2020 Jul 24;9(8):443. [Content Brief]
[2]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99. [Content Brief]
[4]. Guo H, et al., Effects of isopropyl palmitate on the skin permeation of drugs. Biol Pharm Bull. 2006 Nov;29(11):2324-6. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3500 mL | 16.7499 mL | 33.4997 mL | 83.7493 mL |
| 5 mM | 0.6700 mL | 3.3500 mL | 6.6999 mL | 16.7499 mL | |
| 10 mM | 0.3350 mL | 1.6750 mL | 3.3500 mL | 8.3749 mL | |
| 15 mM | 0.2233 mL | 1.1167 mL | 2.2333 mL | 5.5833 mL | |
| 20 mM | 0.1675 mL | 0.8375 mL | 1.6750 mL | 4.1875 mL | |
| 25 mM | 0.1340 mL | 0.6700 mL | 1.3400 mL | 3.3500 mL | |
| 30 mM | 0.1117 mL | 0.5583 mL | 1.1167 mL | 2.7916 mL |
- Isopropyl
- 142-91-6
- Propan-2-yl hexadecanoate
- Environmental Pollutants
- Liposome
- Biochemical Assay Reagents
- pharmaceutical excipient
- pharmaceutical auxiliarie
- pharmaceutical ingredients
- inactive ingredients
- stability
- solubility
- processability
- absorption
- distribution
- metabolism
- and elimination (ADME)
- Inhibitor
- inhibitor
- inhibit