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  4. PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization)

PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization)  (Synonyms: Polyvinyl alcohol (Mw 27000, 98-99% hydrolyzed, ~600 polymerization); Poly(Ethenol) (Mw 27000, 98-99% hydrolyzed, ~600 polymerization))

Cat. No.: HY-Y0850U5
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PVA (Polyvinyl alcohol) (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) is a nonionic ethanol homopolymer with hydrophilicity, water solubility and biodegradability. PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) exhibits biocompatibility, non-toxicity and non-carcinogenicity, as well as antibacterial activity against Gram-positive bacteria, Gram-negative bacteria and fungal strains. PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) can serve as a solubilizer, stabilizer, mucoadhesive agent and sustained-release agent, and has a synergistic solubilizing effect on voriconazole/sulfobutyl ether β-cyclodextrin complexes. By stabilizing such complexes, PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) forms freeze-thaw hydrogels with high mucoadhesion, sustained drug release and ex vivo corneal permeability. When compounded with hyaluronic acid hydrogels, PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) supports chondrocyte growth in vitro, and also forms complexes with Cu2+, Co2+, Ni2+ and Zn2+ ions. PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) can be used in studies related to fungal keratitis, bacterial infections and fungal infections.

For research use only. We do not sell to patients.

PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization)

PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) Chemical Structure

CAS No. : 9002-89-5

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PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) Related Antibodies

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Description

PVA (Polyvinyl alcohol) (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) is a nonionic ethanol homopolymer with hydrophilicity, water solubility and biodegradability. PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) exhibits biocompatibility, non-toxicity and non-carcinogenicity, as well as antibacterial activity against Gram-positive bacteria, Gram-negative bacteria and fungal strains. PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) can serve as a solubilizer, stabilizer, mucoadhesive agent and sustained-release agent, and has a synergistic solubilizing effect on voriconazole/sulfobutyl ether β-cyclodextrin complexes. By stabilizing such complexes, PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) forms freeze-thaw hydrogels with high mucoadhesion, sustained drug release and ex vivo corneal permeability. When compounded with hyaluronic acid hydrogels, PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) supports chondrocyte growth in vitro, and also forms complexes with Cu2+, Co2+, Ni2+ and Zn2+ ions. PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) can be used in studies related to fungal keratitis, bacterial infections and fungal infections[1][2][3].

In Vitro

PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) (Cu(II) ion: 0.01 Mol dm-3; PVA: 0.01 Mol dm-3) forms a binary complex with Cu2+ ions in aqueous solution, as confirmed by a blue shift in the visible absorption spectrum to a maximum at ~640 nm[3].
PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) (1-5 mg/mL; 24-48 h) exhibits antimicrobial activity, with 5 mg/mL concentrations producing 7-8 mm inhibition zones against tested bacteria and 12 mm inhibition zones against tested fungi[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) Related Antibodies

Cell Viability Assay[3]

Cell Line: Staphylococcus aureus and Bacillus subtillis
Concentration: 1-5 mg/mL
Incubation Time: 24-48 h
Result: Exhibited antimicrobial activity, producing 7-8 mm inhibition zones against tested bacteria and 12 mm inhibition zones against tested fungi.
Molecular Weight

27000 (Average)

Formula

(C2H4O)n
CAS No.
SMILES

CCC(O)C.[n]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization)9002-89-5Polyvinyl alcohol (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) Poly(Ethenol) (Mw 27000, 98-99% hydrolyzed, ~600 polymerization)Biochemical Assay ReagentsFungalchondrocytefreeze-thaw hydrogelshyaluronic acid hydrogelsGram-negative bacteriafungal keratitisbacterial infectionsGram-positive bacteriafungal infectionsvoriconazole/sulfobutyl ether β-cyclodextrin complexesfungal strainsInhibitorinhibitorinhibit

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