Diammonium

By Targets:	Amyloid-β (3) Apoptosis (1) Bacterial (2) Biochemical Assay Reagents (1) DNA/RNA Synthesis (1) Endogenous Metabolite (6) Fluorescent Dye (3) Isotope-Labeled Compounds (1) P2Y Receptor (1) Phosphatase (1) PI3K (1) STING (6) TGF-beta/Smad (1) Virus Protease (1)
By Research Areas:	Cancer (7) Cardiovascular Disease (1) Infection (3) Inflammation/Immunology (5) Metabolic Disease (3) Neurological Disease (3)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N6804

Diammonium Glycyrrhizinate

Others Inflammation/Immunology Cancer

Diammonium Glycyrrhizinate, isolated from the licorice root, is a widely used anti-inflammatory agent .

Diammonium Glycyrrhizinate	Others	Inflammation/Immunology Cancer
Diammonium Glycyrrhizinate, isolated from the licorice root, is a widely used anti-inflammatory agent .

HY-Y0302

Diammonium phosphate
Diammonium phosphate is a neutral and efficient catalyst in 1,8‐Dioxo‐octahydroxanthene derivatives synthesis. Diammonium phosphate can be used as an excipient, such as diuretic, buffer, effervescent. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

HY-111999A

*E7766 diammonium* salt**	STING	Cancer
E7766 diammonium salt is a macrocycle-bridged STING agonist with a K_d of 40 nM. E7766 diammonium salt shows potent pan-genotypic and antitumor activities .

HY-W109973

L-Tartaric acid diammonium L-(+)-Tartaric acid Diammonium	Endogenous Metabolite	Cardiovascular Disease
L-Tartaric acid diammonium (L-(+) -tartaric acid) is an orally active weak organic acid that can be isolated from grapes. L-Tartaric acid diammonium has vasodilatory and antihypertensive effects. L-Tartaric acid diammonium can be used as flavorings and antioxidants in a range of foods and beverages. L-Tartaric acid diammonium can be used in laser frequency doubling and optical limiting applications .

HY-D1739

DDAO phosphate diammonium	Fluorescent Dye	Others
DDAO phosphate diammonium is a fluorescent phosphatase substrate. DDAO phosphate diammonium has tunable excitation wavelength (600-650nm) and long emission wavelength (λem=656nm). DDAO phosphate diammonium can be used to detect the activity of different enzymes such as β-galactosidase, sulfatase, protein phosphatase 2A, carboxylesterase 2, human albumin and esterase.

HY-107780B

Cyclic-di-GMP diammonium 2 Publications Verification c-di-GMP Diammonium; cyclic diguanylate Diammonium; 5GP-5GP Diammonium	STING Endogenous Metabolite	Cancer
Cyclic-di-GMP diammonium is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP diammonium has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP diammonium can be used in cancer research .

HY-W127789

Ethylenediaminetetraacetic acid diammonium EDTA Diammonium	Biochemical Assay Reagents	Others
Ethylenediaminetetraacetic acid diammonium salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-P0118B

Disitertide diammonium Maximum Cited Publications 11 Publications Verification P144 Diammonium	TGF-beta/Smad PI3K Apoptosis	Cancer
Disitertide (P144) diammonium is a peptidic transforming growth factor-beta 1 (TGF-β1) inhibitor specifically designed to block the interaction with its receptor. Disitertide diammonium is also a PI3K inhibitor and an apoptosis inducer .

HY-130115B

IACS-8803 diammonium

STING Cancer

IACS-8803 diammonium is a highly potent cyclic dinucleotide STING agonist. IACS-8803 diammonium has a robust systemic antitumor efficacy .

IACS-8803 diammonium	STING	Cancer
IACS-8803 diammonium is a highly potent cyclic dinucleotide STING agonist. IACS-8803 diammonium has a robust systemic antitumor efficacy .

HY-110385A

cGAMP diammonium 5+ Cited Publications Cyclic GMP-AMP Diammonium; 3',3'-cGAMP Diammonium	STING Endogenous Metabolite	Inflammation/Immunology
cGAMP (Cyclic GMP-AMPP) diammonium functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. cGAMP diammonium activates stimulator of interferon genes (STING), which activates a signaling cascade leading to the production of type I interferons and other immune mediators .

HY-12326B

c-di-AMP diammonium 2 Publications Verification Cyclic diadenylate Diammonium; Cyclic-di-AMP Diammonium	STING Bacterial Endogenous Metabolite	Inflammation/Immunology
c-di-AMP diammonium is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP diammonium is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. c-di-AMP diammonium acts as a potent mucosal adjuvant stimulating both humoral and cellular responses .

HY-105967A

Dicresulene diammonium

Bacterial Infection

Dicresulene diammonium is an impurity of Policresulen, an organic acid with hemostatic, antimicrobial and antiviral activities .

Dicresulene diammonium	Bacterial	Infection
Dicresulene diammonium is an impurity of Policresulen, an organic acid with hemostatic, antimicrobial and antiviral activities .

HY-108657A

MRS2279 diammonium 1 Publications Verification	P2Y Receptor	Neurological Disease
MRS2279 diammonium is a selective and high affinity P2Y1 receptor antagonist, with a K_i value of 2.5 nM and an IC₅₀ value of 51.6 nM. MRS2279 diammonium competitively inhibits ADP-promoted platelet aggregation with an pK_b value of 8.05 .

HY-D0101

Fluorescein-diphosphat diammonium	Fluorescent Dye
Fluorescein-diphosphat (diammonium) is a colorimetric probe formed by the reaction of adipic acid dihydrazide and fluorescein isothiocyanate.

HY-15902

ABTS diammonium salt

2 Publications Verification

AzBTS-(NH4)2
Fluorescent Dye Others

ABTS diammonium salt is a substrate for horseradish peroxidase (HRP) conjugate.

*ABTS diammonium* salt** 2 Publications Verification AzBTS-(NH4)2	Fluorescent Dye	Others
ABTS diammonium salt is a substrate for horseradish peroxidase (HRP) conjugate.

HY-14519S1

Methotrexate-d3 diammonium	Isotope-Labeled Compounds	Metabolic Disease Inflammation/Immunology Cancer
Methotrexate-d₃ diammonium is the deuterium labeled Methotrexate diammonium. Methotrexate (Amethopterin), an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia) .

HY-15133A

PTP1B-IN-3 diammonium	Phosphatase	Metabolic Disease Cancer
PTP1B-IN-3 diammonium is a potent and orally active PTP1B inhibitor with IC₅₀s of 120 nM for both PTP1B and TCPTP. PTP1B-IN-3 diammonium has antidiabetic and anticancer effects .

HY-N8515B

UDP-3-O-acyl-GlcNAc diammonium UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine Diammonium	Endogenous Metabolite	Others
UDP-3-O-acyl-GlcNAc diammonium is an E. coli metabolite that is involved in 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway .

HY-139100B

N7-Methyl-guanosine-5'-triphosphate-5'-adenosine diammonium m7GpppA Diammonium	DNA/RNA Synthesis	Infection
N7-Methyl-guanosine-5'-triphosphate-5'-adenosine (m7GpppA) diammonium is a dinucleotide cap analog that can be used for in vitro RNA transcription .

HY-136573

5-Hydroxytoluene-2,4-disulphonic acid diammonium	Virus Protease	Infection
5-Hydroxytoluene-2,4-disulphonic acid diammonium is an impurity of Policresulen. Policresulen is a potent NS2B/NS3 protease inhibitor with an IC₅₀ of 0.48 μg/mL. Policresulen effectively inhibits the replication of DENV2 virus in BHK-21 cells with an IC₅₀ of 4.99 μg/mL. Policresulen acted as a competitive inhibitor of the protease, and slightly affected the protease stability .

HY-146248B

TFMU-ADPr diammonium	Others	Metabolic Disease
TFMU-ADPr is a universal substrate for monitoring PARG activity. TFMU-ADPr directly reports the total bar number hydrolase activity by releasing fluorophore. TFMU-ADPr is a general tool for evaluating small molecule inhibitors and exploring the regulation of ADP-ribose catabolic enzymes in vitro .

HY-P3860

*Biotinyl-Amyloid β-Protein (1-42) (ammonium)*	Amyloid-β	Neurological Disease
Biotinyl-Amyloid β-Protein (1-42) ammonium is a biotinylated Amyloid β-Protein (1-42) (HY-P1363). Biotinyl-Amyloid β-Protein (1-42) ammonium can be used for the research of Aβ1-42 converts to Aβ1-40 in brain .

HY-P3783

(Nle35)-Amyloid β-Protein (1-42) (ammonium)

Amyloid-β Others

(Nle35)-Amyloid β-Protein (1-42) ammonium is a peptide.

*(Nle35)-Amyloid β-Protein (1-42) (ammonium)*	Amyloid-β	Others
(Nle35)-Amyloid β-Protein (1-42) ammonium is a peptide.

HY-P3908

*FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium)*	Amyloid-β	Neurological Disease
FITC-β-Ala-Amyloid β-Protein (1-42) ammonium is a FITC tagged Aβ1-42 monomer peptide. Aβ1-42 plays a key role in the pathogenesis of Alzheimer’s disease .

HY-110385

cGAMP disodium 5+ Cited Publications Cyclic GMP-AMP disodium; 3',3'-cGAMP disodium	STING Endogenous Metabolite	Inflammation/Immunology
cGAMP (Cyclic GMP-AMPP) disodium functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. cGAMP diammonium activates stimulator of interferon genes (STING), which activates a signaling cascade leading to the production of type I interferons and other immune mediators .

Cat. No.	Product Name	Type

HY-15902

ABTS diammonium salt

2 Publications Verification

AzBTS-(NH4)2
Chromogenic Substrates

ABTS diammonium salt is a substrate for horseradish peroxidase (HRP) conjugate.

*ABTS diammonium* salt** 2 Publications Verification AzBTS-(NH4)2	Chromogenic Substrates
ABTS diammonium salt is a substrate for horseradish peroxidase (HRP) conjugate.

HY-D1739

DDAO phosphate diammonium	Fluorescent Dyes/Probes
DDAO phosphate diammonium is a fluorescent phosphatase substrate. DDAO phosphate diammonium has tunable excitation wavelength (600-650nm) and long emission wavelength (λem=656nm). DDAO phosphate diammonium can be used to detect the activity of different enzymes such as β-galactosidase, sulfatase, protein phosphatase 2A, carboxylesterase 2, human albumin and esterase.

HY-D0101

Fluorescein-diphosphat diammonium

Dyes

Fluorescein-diphosphat (diammonium) is a colorimetric probe formed by the reaction of adipic acid dihydrazide and fluorescein isothiocyanate.

Fluorescein-diphosphat diammonium	Dyes
Fluorescein-diphosphat (diammonium) is a colorimetric probe formed by the reaction of adipic acid dihydrazide and fluorescein isothiocyanate.

Cat. No.	Product Name	Type

HY-W109973

L-Tartaric acid diammonium L-(+)-Tartaric acid Diammonium	Biochemical Assay Reagents
L-Tartaric acid diammonium (L-(+) -tartaric acid) is an orally active weak organic acid that can be isolated from grapes. L-Tartaric acid diammonium has vasodilatory and antihypertensive effects. L-Tartaric acid diammonium can be used as flavorings and antioxidants in a range of foods and beverages. L-Tartaric acid diammonium can be used in laser frequency doubling and optical limiting applications .

L-Tartaric acid diammonium

L-(+)-Tartaric acid Diammonium

Biochemical Assay Reagents

L-Tartaric acid diammonium (L-(+) -tartaric acid) is an orally active weak organic acid that can be isolated from grapes. L-Tartaric acid diammonium has vasodilatory and antihypertensive effects. L-Tartaric acid diammonium can be used as flavorings and antioxidants in a range of foods and beverages. L-Tartaric acid diammonium can be used in laser frequency doubling and optical limiting applications .

HY-W127789

Ethylenediaminetetraacetic acid diammonium EDTA Diammonium	Biochemical Assay Reagents
Ethylenediaminetetraacetic acid diammonium salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Cat. No.	Product Name	Target	Research Area

HY-P0118B

Disitertide diammonium 10+ Cited Publications P144 Diammonium	TGF-beta/Smad PI3K Apoptosis	Cancer
Disitertide (P144) diammonium is a peptidic transforming growth factor-beta 1 (TGF-β1) inhibitor specifically designed to block the interaction with its receptor. Disitertide diammonium is also a PI3K inhibitor and an apoptosis inducer .

HY-P3860

*Biotinyl-Amyloid β-Protein (1-42) (ammonium)*	Amyloid-β	Neurological Disease
Biotinyl-Amyloid β-Protein (1-42) ammonium is a biotinylated Amyloid β-Protein (1-42) (HY-P1363). Biotinyl-Amyloid β-Protein (1-42) ammonium can be used for the research of Aβ1-42 converts to Aβ1-40 in brain .

HY-P3783

(Nle35)-Amyloid β-Protein (1-42) (ammonium)

Amyloid-β Others

(Nle35)-Amyloid β-Protein (1-42) ammonium is a peptide.

*(Nle35)-Amyloid β-Protein (1-42) (ammonium)*	Amyloid-β	Others
(Nle35)-Amyloid β-Protein (1-42) ammonium is a peptide.

HY-P3908

*FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium)*	Amyloid-β	Neurological Disease
FITC-β-Ala-Amyloid β-Protein (1-42) ammonium is a FITC tagged Aβ1-42 monomer peptide. Aβ1-42 plays a key role in the pathogenesis of Alzheimer’s disease .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N6804

Diammonium Glycyrrhizinate	Triterpenes Classification of Application Fields Leguminosae Terpenoids Source classification Plants Disease Research Fields Glycyrrhiza uralensis Fisch. Cancer	Others
Diammonium Glycyrrhizinate, isolated from the licorice root, is a widely used anti-inflammatory agent .

HY-107780B

Cyclic-di-GMP diammonium 2 Publications Verification c-di-GMP Diammonium; cyclic diguanylate Diammonium; 5GP-5GP Diammonium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	STING Endogenous Metabolite
Cyclic-di-GMP diammonium is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP diammonium has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP diammonium can be used in cancer research .

HY-110385A

cGAMP diammonium Maximum Cited Publications 7 Publications Verification Cyclic GMP-AMP Diammonium; 3',3'-cGAMP Diammonium	Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Inflammation/Immunology	STING Endogenous Metabolite
cGAMP (Cyclic GMP-AMPP) diammonium functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. cGAMP diammonium activates stimulator of interferon genes (STING), which activates a signaling cascade leading to the production of type I interferons and other immune mediators .

HY-12326B

c-di-AMP diammonium 2 Publications Verification Cyclic diadenylate Diammonium; Cyclic-di-AMP Diammonium	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	STING Bacterial Endogenous Metabolite
c-di-AMP diammonium is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP diammonium is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. c-di-AMP diammonium acts as a potent mucosal adjuvant stimulating both humoral and cellular responses .

HY-W109973

L-Tartaric acid diammonium L-(+)-Tartaric acid Diammonium	Cardiovascular Disease Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
L-Tartaric acid diammonium (L-(+) -tartaric acid) is an orally active weak organic acid that can be isolated from grapes. L-Tartaric acid diammonium has vasodilatory and antihypertensive effects. L-Tartaric acid diammonium can be used as flavorings and antioxidants in a range of foods and beverages. L-Tartaric acid diammonium can be used in laser frequency doubling and optical limiting applications .

HY-N8515B

UDP-3-O-acyl-GlcNAc diammonium UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine Diammonium	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
UDP-3-O-acyl-GlcNAc diammonium is an E. coli metabolite that is involved in 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway .

HY-110385

cGAMP disodium Maximum Cited Publications 7 Publications Verification Cyclic GMP-AMP disodium; 3',3'-cGAMP disodium	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	STING Endogenous Metabolite
cGAMP (Cyclic GMP-AMPP) disodium functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. cGAMP diammonium activates stimulator of interferon genes (STING), which activates a signaling cascade leading to the production of type I interferons and other immune mediators .

Cat. No.	Product Name	Chemical Structure

HY-14519S1

Methotrexate-d3 diammonium

Methotrexate-d₃ diammonium is the deuterium labeled Methotrexate diammonium. Methotrexate (Amethopterin), an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia) .

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Remarks

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Diammonium

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

NaturalProducts

Isotope-Labeled Compounds

Natural
Products