1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. L-Tartaric acid diammonium

L-Tartaric acid diammonium  (Synonyms: L-(+)-Tartaric acid diammonium)

Cat. No.: HY-W109973 Purity: 99.95%
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L-Tartaric acid diammonium (L-(+) -tartaric acid) is an orally active weak organic acid that can be isolated from grapes. L-Tartaric acid diammonium has vasodilatory and antihypertensive effects. L-Tartaric acid diammonium can be used as flavorings and antioxidants in a range of foods and beverages. L-Tartaric acid diammonium can be used in laser frequency doubling and optical limiting applications.

For research use only. We do not sell to patients.

L-Tartaric acid diammonium

L-Tartaric acid diammonium Chemical Structure

CAS No. : 3164-29-2

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
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Based on 1 publication(s) in Google Scholar

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Description

L-Tartaric acid diammonium (L-(+) -tartaric acid) is an orally active weak organic acid that can be isolated from grapes. L-Tartaric acid diammonium has vasodilatory and antihypertensive effects. L-Tartaric acid diammonium can be used as flavorings and antioxidants in a range of foods and beverages. L-Tartaric acid diammonium can be used in laser frequency doubling and optical limiting applications[1][2][3][4].

IC50 & Target

Microbial Metabolite

 

Human Endogenous Metabolite

 

In Vitro

L-Tartaric acid (1.66-6.64 mM) significantly reduces NEP and KCL-induced aortic ring vasoconstriction with EC50 values of 4.119 mM and 4.00 mM, respectively[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

L-Tartaric acid (80-240 mg/kg; P.O.; Single dose) reduces blood pressure in hypertensive mice induced by L-NAME (60 mg/kg) [3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Hypertensive Wistar rat model[3]
Dosage: 80 mg/kg, 240 mg/kg
Administration: Oral gavage (p.o.); Single dose. After L-NAME treatment (60.mg/kg; p.o.)
Result: Reduced systolic blood pressure (SABP) and mild blood pressure (mid-BP) in rats at a dose of 240mg/kg, but had no effect on mean artery pressure, diastolic blood pressure, pulse pressure level, and heart rate.
Molecular Weight

184.15

Formula

C4H12N2O6

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)[C@H](O)[C@@H](O)C(O)=O.N.N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature, keep dry and cool

In solvent -80°C 1 year
-20°C 6 months
Solvent & Solubility
In Vitro: 

H2O : 35 mg/mL (190.06 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.4304 mL 27.1518 mL 54.3036 mL
5 mM 1.0861 mL 5.4304 mL 10.8607 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 5.4304 mL 27.1518 mL 54.3036 mL 135.7589 mL
5 mM 1.0861 mL 5.4304 mL 10.8607 mL 27.1518 mL
10 mM 0.5430 mL 2.7152 mL 5.4304 mL 13.5759 mL
15 mM 0.3620 mL 1.8101 mL 3.6202 mL 9.0506 mL
20 mM 0.2715 mL 1.3576 mL 2.7152 mL 6.7879 mL
25 mM 0.2172 mL 1.0861 mL 2.1721 mL 5.4304 mL
30 mM 0.1810 mL 0.9051 mL 1.8101 mL 4.5253 mL
40 mM 0.1358 mL 0.6788 mL 1.3576 mL 3.3940 mL
50 mM 0.1086 mL 0.5430 mL 1.0861 mL 2.7152 mL
60 mM 0.0905 mL 0.4525 mL 0.9051 mL 2.2626 mL
80 mM 0.0679 mL 0.3394 mL 0.6788 mL 1.6970 mL
100 mM 0.0543 mL 0.2715 mL 0.5430 mL 1.3576 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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L-Tartaric acid diammonium
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