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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
L929 mouse fibroblasts
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "L929 mouse fibroblasts" in MCE Product Catalog:
Cat. No.: HY-N3266
CAS No.: 99353-00-1
Cat. No.: HY-W196368
CAS No.: 2217-60-9
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Cat. No.: HY-W763546A
CAS No.: 26403-72-5
Cat. No.: HY-162418
CAS No.: 3034304-89-4
Antibacterial agent 203 (Compound 5h) has antibacterial and antifungal activity. Antibacterial agent 203 has potent antifungal activity against C. albicans, with a MIC of 3.90 μg/mL. Antibacterial agent 203 has antimicrobial activity on healthy mouse fibroblast cells (L929), with an IC50 of 75.96 μM .
Cat. No.: HY-N14038
CAS No.: 157698-34-5
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Cat. No.: HY-167835A
CAS No.: 2824-94-4
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Alkaloids Other Alkaloids Cymbopetalum brasiliense (Vell.) Benth. ex Baill. Plants Annonaceae
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Cat. No.: HY-N14040
CAS No.: 237425-37-5
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Cat. No.: HY-N15343
CAS No.: 2222286-14-6
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Cat. No.: HY-N14734
CAS No.: 158181-47-6
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Dieugenol is a neolignan that has been found in N. leucantha and has antioxidative and antiprotozoal activities. It inhibits the formation of thiobarbituric acid reactive substances (TBARS) and scavenges superoxide anions, but not hydroxyl radicals, in cell-free assays. It has anti-trypanosomal activity against T. cruzi amastigotes and trypomastigotes (IC50s=15.1 and 11.5 μM, respectively) but is cytotoxic to NCTC L-929 fibroblasts with a 50% cytotoxic concentration (CC50) value of 58.2 μM.2 Dieugenol (15 μM) disrupts the integrity of the T. cruzi trypomastigote plasma membrane but does not induce the production of reactive oxygen species (ROS) in trypomastigotes or LPS-stimulated and unstimulated isolated mouse peritoneal macrophages.
Cat. No.: HY-N14043
CAS No.: 237425-38-6
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Cat. No.: HY-N14044
CAS No.: 237425-39-7
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Cat. No.: HY-187386
CAS No.: 200804-78-0
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dsNec-1 is a radical-trapping antioxidant. dsNec-1 inhibits lipid peroxidation. dsNec-1 inhibits ferroptosis in mouse embryonic fibroblasts .
Cat. No.: HY-W007174
CAS No.: 491-19-0
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Xylitan is a derivative of Xylitol (HY-N0538). Xylitan derivatives exhibit in vitro anti-Trypanosoma cruzi activity. Xylitan can be used for the research of Chagas disease .
Cat. No.: HY-184330
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ALR2/α-Glucosidase-IN-2 is an inhibitor of α-glucosidase and aldose reductase ALR2. ALR2/α-Glucosidase-IN-2 has a Ki value of 11.68 nM against yeast α-glucosidase and a Ki value of 72.64 nM against ovine ALR2. ALR2/α-Glucosidase-IN-2 inhibits intestinal carbohydrate digestion regulatory enzymes and key enzymes in the polyol pathway. ALR2/α-Glucosidase-IN-2 can be used in diabetes-related research .
Cat. No.: HY-182266
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FBP is a mitochondria-targeted, selective anticancer agent. FBP induces oxidative stress and mitochondrial dysfunction, leading to Apoptosis. FBP generates ROS and causes double-strand DNA breaks in cancer cells. FBP exhibits cytotoxic efficacy against cancer cells, with cervical cancer cells being the most sensitive. FBP can be used for the research of cervical cancer, lung cancer, melanoma and breast cancer .
Cat. No.: HY-184503
CAS No.: 1163744-36-2
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MAO-B-IN-59 is a reversible, selective competitive inhibitor of MAO-B, with an IC50 of 0.082 μM against human MAO-B, and exhibits moderate blood-brain barrier permeability. MAO-B-IN-59 can be used in the research of Parkinson's disease .
Cat. No.: HY-184779
CAS No.: 29435-48-1
Synonyms: PHB
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Poly[(R)-3-hydroxybutyrate] (PHB) is a polyhydroxyalkanoate polymer with biocompatibility and processability. Poly[(R)-3-hydroxybutyrate] can be used to prepare drug delivery nanoparticles and tissue engineering scaffolds. Poly[(R)-3-hydroxybutyrate] is applicable to research related to drug delivery, tissue engineering and wound dressing materials .
Cat. No.: HY-181267
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ALDOA-IN-1 is an aldolase A(ALDOA) inhibitor. ALDOA-IN-1 directly inhibits ALDOA enzymatic activity, thereby reducing lactate production, downregulating HIF-1α expression, and ultimately inducing cancer cell apoptosis. ALDOA-IN-1 can be used for research on colorectal cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
