Search Result

Results for "

Triiodothyronine

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Androgen Receptor (3) Bacterial (3) Biochemical Assay Reagents (1) Cytochrome P450 (4) Drug Metabolite (1) Endogenous Metabolite (21) Environmental Pollutants (1) Estrogen Receptor/ERR (3) Histamine Receptor (1) Isotope-Labeled Compounds (9) Melanocortin Receptor (1) Reference Standards (8) Somatostatin Receptor (1) Thyroid Hormone Receptor (31)
By Research Areas:	Cancer (19) Cardiovascular Disease (2) Endocrinology (25) Infection (3) Metabolic Disease (8) Neurological Disease (4)

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

GMP Molecules

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-A0070A

Liothyronine Maximum Cited Publications 39 Publications Verification Triiodothyronine; 3,3',5-Triiodo-L-thyronine; T3	Thyroid Hormone Receptor Endogenous Metabolite	Endocrinology Cancer
Liothyronine is an active form of thyroid hormone. Liothyronine binds to thyroid hormone receptors TRα and TRβ with K_is of 2.33 and 2.29 nM for hTRα and hTRβ, respectively. Liothyronine also binds to PVR and blocks the interaction of TIGIT/PVR .

HY-A0070

Liothyronine sodium Maximum Cited Publications 39 Publications Verification Triiodothyronine sodium; 3,3',5-Triiodo-L-thyronine sodium; T3 sodium	Thyroid Hormone Receptor Endogenous Metabolite	Endocrinology Cancer
Liothyronine sodium is an active form of thyroid hormone. Liothyronine sodium is a potent thyroid hormone receptors TRα and TRβ agonist with K_is of 2.33 nM for hTRα and hTRβ, respectively .

HY-18341

L-Thyroxine 10+ Cited Publications Levothyroxine; T4	Thyroid Hormone Receptor Endogenous Metabolite	Endocrinology Cancer
L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .

HY-107903

Thyroglobulin Thyroglobulin from bovine	Biochemical Assay Reagents	Cancer
Thyroglobulin is a 660 kDa, dimeric glycoprotein produced by the follicular cells of the thyroid and used entirely within the thyroid gland. Thyroglobulin acts as a substrate for the synthesis of the thyroid hormones thyroxine (T4) and triiodothyronine (T3), as well as the storage of the inactive forms of thyroid hormone and iodine within the follicular lumen of a thyroid follicle. Thyroglobulin activates Akt kinase activity in FRTL-5 thyroid cell .

HY-18341B

L-Thyroxine sodium 10+ Cited Publications Levothyroxine sodium; T4 sodium	Thyroid Hormone Receptor Endogenous Metabolite	Endocrinology Cancer
L-Thyroxine sodium (Levothyroxine sodium) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .

HY-D0896

ANS 1 Publications Verification ANSA; 8-Anilino-1-naphthalenesulfonic acid	Bacterial	Infection
ANS (8-Anilino-1-naphthalenesulfonic acid) is a competitive inhibitor targeting thyroxine binding globulin (TBG) (K_i=2.09×10 ⁶ M ^-1). ANS is used in radioimmunoassay by displacing bound triiodothyronine (T3) to improve detection sensitivity. ANS can block the protein binding site of T3 and release free T3 for antibody recognition. As a fluorescent probe, ANS can specifically bind to the hydrophobic region of proteins (such as membrane proteins) and monitor the dynamics of protein conformation through changes in fluorescent signals. It is widely used in biochemical research and antibacterial material development .

HY-A0070B

Liothyronine sodium hydrate Maximum Cited Publications 39 Publications Verification Triiodothyronine sodium hydrate; 3,3',5-Triiodo-L-thyronine sodium hydrate; T3 sodium hydrate	Thyroid Hormone Receptor Endogenous Metabolite	Endocrinology Cancer
Liothyronine sodium hydrate is an active form of thyroid hormone. Liothyronine sodium hydrate is a potent thyroid hormone receptors TRα and TRβ agonist with K_is of 2.33 nM for hTRα and hTRβ, respectively .

HY-B1234

Octinoxate Octyl methoxycinnamate	Environmental Pollutants Estrogen Receptor/ERR Androgen Receptor Cytochrome P450 Thyroid Hormone Receptor	Metabolic Disease Endocrinology
Octinoxate (Octyl methoxycinnamate) is a thyroid hormone receptor agonist, reducing the levels of triiodothyronine (T3) and thyroxine (T4) and transcription levels of genes related to type II deiodinase (deio2) in Japanese Medaka. Octinoxate is commonly used as a safe ultraviolet (UV) filter used in the aquatic environment. Octinoxate inhibits CYP1A1 and CYP1B1 to regulate hyaluronan (HA) (HY-B0633A) metabolism in a PI3K pathway-dependent manner in human keratinocytes. Octinoxate also exhibits an anti-estrogenic and anti-androgenic effect in vitro and in vivo .

HY-A0070AG

Liothyronine 1 Publications Verification Triiodothyronine; 3,3',5-Triiodo-L-thyronine; T3	Thyroid Hormone Receptor	Endocrinology Cancer
Liothyronine (Triiodothyronine) (GMP) is the Liothyronine (HY-A0070A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with K_is of 2.33 nM for hTRα and hTRβ, respectively .

HY-W010696

Reverse T3 2 Publications Verification 3′,5′,3-Triiodothyronine	Thyroid Hormone Receptor	Cardiovascular Disease
Reverse T3 is a thyroid hormone that can be generated by deiodination of the prohormone thyroxine . Reverse T3 inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes .

HY-A0070AR

Liothyronine (Standard) 30+ Cited Publications Triiodothyronine (Standard); 3,3',5-Triiodo-L-thyronine (Standard); T3 (Standard)	Thyroid Hormone Receptor Endogenous Metabolite Reference Standards	Endocrinology Cancer
Liothyronine (Standard) is the analytical standard of Liothyronine. This product is intended for research and analytical applications. Liothyronine is an active form of thyroid hormone. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with K_is of 2.33 nM for hTRα and hTRβ, respectively .

HY-18341A

L-Thyroxine sodium salt pentahydrate 10+ Cited Publications Sodium levothyroxine pentahydrate	Thyroid Hormone Receptor Endogenous Metabolite	Endocrinology Cancer
L-Thyroxine sodium salt pentahydrate (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .

HY-126996

Triiodothyronine sulfate	Drug Metabolite Endogenous Metabolite	Metabolic Disease
Triiodothyronine sulfate is the main metabolite of thyroid hormone triiodothyronine (T3). Triiodothyronine is an active form of thyroid hormone, which binds to β1 thyroid hormone receptor (TRβ1), and activates its activity .

HY-18341R

L-Thyroxine (Standard) Levothyroxine (Standard); T4 (Standard)	Reference Standards Thyroid Hormone Receptor Endogenous Metabolite	Endocrinology Cancer
L-Thyroxine (Standard) is the analytical standard of L-Thyroxine. This product is intended for research and analytical applications. L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .

HY-A0069

Doxylamine succinate	Histamine Receptor Cytochrome P450	Neurological Disease Metabolic Disease
Doxylamine succinate is a first-generation antihistamine and acts as a histamine H1 receptor antagonist. Doxylamine succinate is orally active, possessing analgesic and hypnotic activities. Doxylamine succinate enhances the activities of CYP2B, CYP2A, CYP3A and thyroxine-glucuronosyltransferase via promoting substrate hydroxylation and thyroxine metabolic pathways. Doxylamine succinate decreases serum thyroxine (T4) level and elevates serum thyroid-stimulating hormone (TSH) level. Doxylamine succinate induces liver enlargement and increases the activities of hepatic microsomal cytochrome P450, cytochrome b5 and NADPH-cytochrome c reductase. Doxylamine succinate can be used for the research of nausea, allergy, insomnia .

HY-18341S2

L-Thyroxine-13C6	Thyroid Hormone Receptor Endogenous Metabolite	Endocrinology
L-Thyroxine- ¹³C₆ is the ¹³C labeled L-Thyroxine . L-Thyroxine (Levothyroxine;T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .

HY-D0896A

ANS ammonium 1 Publications Verification NSC 1746 ammonium; Peri acid, phenyl- ammonium; Phenyl peri acid ammonium	Bacterial	Infection
ANS ammonium is a potent antibacterial agent and a textile dye. ANS ammonium can be used as fluorescence probe. ANS ammonium blocks the binding of triiodothyronine to thyroxine binding globulin in radioimmunoassay of triiodothyronine .

HY-W010669

L-Thyroxine sodium xhydrate Maximum Cited Publications 11 Publications Verification Sodium levothyroxine	Thyroid Hormone Receptor	Endocrinology
L-Thyroxine sodium xhydrate (Levothyroxine; T4) is a synthetic hormone in the treatment of hypothyroidism. DIO enzymes convert biologically active hormone (Triiodothyronine,T3) from L-Thyroxine (T4).

HY-141939S

Liothyronine-13C6 hydrochloride Triiodothyronine-¹³C₆; 3,3',5-Triiodo-L-thyronine-¹³C₆; T3-¹³C₆	Isotope-Labeled Compounds	Others
Triiodothyronine- ¹³C₆ (hydrochloride) is the ¹³C labeled Triiodothyronine .

HY-18341F

Biotin-(L-Thyroxine)	Thyroid Hormone Receptor Endogenous Metabolite	Endocrinology
Biotin-(L-Thyroxine) is the biotinylated L-Thyroxine (HY-18341). L-Thyroxine is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from Biotin-(L-Thyroxine) (T4) .

HY-A0070R

Liothyronine sodium (Standard) Triiodothyronine sodium (Standard); 3,3',5-Triiodo-L-thyronine sodium (Standard); T3 sodium (Standard)	Reference Standards Thyroid Hormone Receptor Endogenous Metabolite	Endocrinology Cancer
Liothyronine (sodium) (Standard) is the analytical standard of Liothyronine (sodium). This product is intended for research and analytical applications. Liothyronine sodium is an active form of thyroid hormone. Liothyronine sodium is a potent thyroid hormone receptors TRα and TRβ agonist with K_is of 2.33 nM for hTRα and hTRβ, respectively .

HY-127024A

TR antagonist 2	Thyroid Hormone Receptor	Metabolic Disease
TR antagonist 2 (Compound 10a) is a competitive thyroid hormone receptors (TRα/β) antagonist (IC₅₀=47 nM). TR antagonist 2 competes with triiodothyronine (T₃) for binding to the ligand-binding domain of TR to block receptor-coactivator complex formation and inhibit target gene transcription, reducing thyroid hormone-mediated hypermetabolic effects. TR antagonist 2 is promising for research of hyperthyroidism (e.g., Graves' disease) and thyrotoxicosis .

HY-A0070AS1

Liothyronine-13C9,15N Triiodothyronine-¹³C₉,¹⁵N; 3,3',5-Triiodo-L-thyronine-¹³C₉,¹⁵N; T3-¹³C₉,¹⁵N	Thyroid Hormone Receptor Endogenous Metabolite	Cancer
Liothyronine- ¹³C₉, ¹⁵N is the ¹³C and ¹⁵N labeled Liothyronine . Liothyronine is an active form of thyroid hormone. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with K_is of 2.33 nM for hTRα and hTRβ, respectively .

HY-W010696R

Reverse T3 (Standard) 3′,5′,3-Triiodothyronine (Standard)	Reference Standards Thyroid Hormone Receptor	Cardiovascular Disease
Reverse T3 (Standard) is the analytical standard of Reverse T3. This product is intended for research and analytical applications. Reverse T3 is a thyroid hormone that can be generated by deiodination of the prohormone thyroxine . Reverse T3 inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes .

HY-A0070C

Liothyronine hydrochloride Triiodothyronine hydrochloride; 3,3',5-Triiodo-L-thyronine hydrochloride; T3 hydrochloride	Thyroid Hormone Receptor Endogenous Metabolite	Endocrinology Cancer
Liothyronine hydrochloride is an active form of thyroid hormone. Liothyronine hydrochloride is a potent thyroid hormone receptors TRα and TRβ agonist with K_is of 2.33 nM for hTRα and hTRβ, respectively .

HY-A0070AS3

Liothyronine-d3 Triiodothyronine-d₃; 3,3',5-Triiodo-L-thyronine-d₃; T3-d₃	Endogenous Metabolite Thyroid Hormone Receptor Isotope-Labeled Compounds	Endocrinology Cancer
Liothyronine-d₃ is deuterated labeled Liothyronine (HY-A0070A). Liothyronine is an active form of thyroid hormone. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with K_is of 2.33 nM for hTRα and hTRβ, respectively .

HY-A0070AS2

Liothyronine-13C6-1 Triiodothyronine-¹³C₆-1; 3,3',5-Triiodo-L-thyronine-¹³C₆-1; T3-¹³C₆-1	Thyroid Hormone Receptor	Endocrinology Cancer
Liothyronine- ¹³C₆-1 is a ¹³C-labeled Liothyronine. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with K_is of 2.33 nM for hTRα and hTRβ, respectively .

HY-A0070AS5

Liothyronine-d4 Triiodothyronine-d₄; 3,3',5-Triiodo-L-thyronine-d₄; T3-d₄	Isotope-Labeled Compounds Thyroid Hormone Receptor Endogenous Metabolite	Endocrinology Cancer
Liothyronine-d₄ (Triiodothyronine-d₄) is the deuterium labeled Liothyronine (HY-A0070A). Liothyronine is an active form of thyroid hormone. Liothyronine binds to thyroid hormone receptors TRα and TRβ with vs of 2.33 and 2.29 nM for hTRα and hTRβ, respectively. Liothyronine also binds to PVR and blocks the interaction of TIGIT/PVR .

HY-D0896AR

ANS ammonium (Standard) NSC 1746 ammonium (Standard); Peri acid, phenyl- ammonium (Standard); Phenyl peri acid ammonium (Standard)	Bacterial Reference Standards	Infection
ANS (ammonium) (Standard) is the analytical standard of ANS (ammonium). This product is intended for research and analytical applications. ANS ammonium is a potent antibacterial agent and a textile dye. ANS ammonium can be used as fluorescence probe. ANS ammonium blocks the binding of triiodothyronine to thyroxine binding globulin in radioimmunoassay of triiodothyronine .

HY-P3567

*(p-Iodo-Phe7)-ACTH (4-10)*	Melanocortin Receptor	Neurological Disease
(p-Iodo-Phe7)-ACTH (4-10) is a adrenocorticotrophic hormone (ACTH) derivative, which is produced and secreted by the anterior pituitary gland. (p-Iodo-Phe7)-ACTH (4-10) serves as a melanocortin (MC) receptor antagonist and inhibits α-melanocyte-stimulating hormone (α-MSH)-induced excessive grooming behavior in rats .

HY-W010696AS

Reverse T3-13C6 hydrochloride 3′,5′,3-Triiodothyronine-13C6 hydrochloride	Thyroid Hormone Receptor Isotope-Labeled Compounds	Others
Reverse T3- ¹³C₆ (hydrochloride) is the ¹³C labeled Reverse T3 .

HY-P2434

AP102	Somatostatin Receptor	Neurological Disease Metabolic Disease Cancer
AP102 is a dual SSTR2/SSTR5-specific somatostatin analog (SSA). AP102 is a disulfide-bridged octapeptide SSA containing synthetic iodinated amino acids. AP102 binds with subnanomolar affinity to SSTR2 and SSTR5 (IC₅₀: 0.63 and 0.65 nM, respectively). AP102 does not bind to SSTR1 or SSTR3. AP102 can be used for acromegaly and neuroendocrine tumors research .

HY-18341BR

L-Thyroxine sodium (Standard) Levothyroxine sodium (Standard); T4 sodium (Standard)	Reference Standards Thyroid Hormone Receptor Endogenous Metabolite	Endocrinology Cancer
L-Thyroxine (sodium) (Standard) is the analytical standard of L-Thyroxine (sodium). This product is intended for research and analytical applications. L-Thyroxine sodium (Levothyroxine sodium) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .

HY-18341S1

Thyroxine hydrochloride-13C6 Levothyroxine-¹³C₆; T4-¹³C₆	Isotope-Labeled Compounds Thyroid Hormone Receptor Endogenous Metabolite	Endocrinology
Thyroxine hydrochloride- ¹³C₆ is the ¹³C-labeled L-Thyroxine. L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .

HY-W010669R

L-Thyroxine sodium xhydrate (Standard) Sodium levothyroxine (Standard)	Reference Standards Thyroid Hormone Receptor	Endocrinology
L-Thyroxine sodium xhydrate (Standard) is the analytical standard of L-Thyroxine sodium xhydrate. This product is intended for research and analytical applications. L-Thyroxine sodium xhydrate (Levothyroxine; T4) is a synthetic hormone in the treatment of hypothyroidism. DIO enzymes convert biologically active hormone (Triiodothyronine,T3) from L-Thyroxine (T4).

HY-18341S4

L-Thyroxine-13C6-1 Levothyroxine-¹³C₆-1; T4-¹³C₆-1	Isotope-Labeled Compounds Endogenous Metabolite Thyroid Hormone Receptor	Endocrinology
L-Thyroxine- ¹³C₆-1 (Levothyroxine- ¹³C₆-1; T4- ¹³C₆-1) is a ¹³C labeled L-Thyroxine (HY-18341). L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .

HY-135956

T3 Acyl glucuronide	Endogenous Metabolite	Metabolic Disease
T3 Acyl glucuronide, an endogenous metabolite, is the acyl glucuronide formation of triiodothyronine (T3) .

HY-W779345

Reverse T3-13C6 3′,5′,3-Triiodothyronine-¹³C₆	Isotope-Labeled Compounds	Others
3,3',5'-Triiodo-L-thyronine- ¹³C₆ is ¹³C labeled 3,3',5'-Triiodo-L-thyronine .

HY-18341AR

L-Thyroxine sodium salt pentahydrate (Standard) Sodium levothyroxine pentahydrate (Standard)	Thyroid Hormone Receptor Endogenous Metabolite Reference Standards	Endocrinology Cancer
L-Thyroxine (sodium salt pentahydrate) (Standard) is the analytical standard of L-Thyroxine (sodium salt pentahydrate). This product is intended for research and analytical applications. L-Thyroxine sodium salt pentahydrate (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .

HY-B1234S

Octinoxate-13C,d3	Cytochrome P450 Thyroid Hormone Receptor Androgen Receptor Estrogen Receptor/ERR Isotope-Labeled Compounds	Metabolic Disease Endocrinology
Octinoxate-13C,d3 is the deuterium labeled Octinoxate (HY-W245806). Octinoxate (Octyl methoxycinnamate) is a thyroid hormone receptor agonist, reducing the levels of triiodothyronine (T3) and thyroxine (T4) and transcription levels of genes related to type II deiodinase (deio2) in Japanese Medaka. Octinoxate is commonly used as a safe ultraviolet (UV) filter used in the aquatic environment. Octinoxate inhibits CYP1A1 and CYP1B1 to regulate hyaluronan (HA) (HY-B0633A) metabolism in a PI3K pathway-dependent manner in human keratinocytes. Octinoxate also exhibits an anti-estrogenic and anti-androgenic effect in vitro and in vivo .

HY-W713284

2-Ethylhexyl (E)-3-(4-(methoxy-d3)phenyl)acrylate	Isotope-Labeled Compounds Cytochrome P450 Estrogen Receptor/ERR Androgen Receptor Thyroid Hormone Receptor	Endocrinology
2-Ethylhexyl (E)-3-(4-(methoxy-d₃)phenyl)acrylate is the deuterium labeled Octinoxate (HY-B1234). Octinoxate (Octyl methoxycinnamate) is a thyroid hormone receptor agonist, reducing the levels of triiodothyronine (T3) and thyroxine (T4) and transcription levels of genes related to type II deiodinase (deio2) in Japanese Medaka. Octinoxate is commonly used as a safe ultraviolet (UV) filter used in the aquatic environment. Octinoxate inhibits CYP1A1 and CYP1B1 to regulate hyaluronan (HA) (HY-B0633A) metabolism in a PI3K pathway-dependent manner in human keratinocytes. Octinoxate also exhibits an anti-estrogenic and anti-androgenic effect in vitro and in vivo .

HY-182688

ITYR-DBRMD	Thyroid Hormone Receptor	Neurological Disease
ITYR-DBRMD is a type III deiodinase (DIO3) inhibitor. ITYR-DBRMD shows antidepressant-like activity and reduces latency to feed in mice. ITYR-DBRMD can be used for the research of depression .

Cat. No.	Product Name	Type

HY-D0896

ANS 1 Publications Verification ANSA; 8-Anilino-1-naphthalenesulfonic acid	Fluorescent Dyes
ANS (8-Anilino-1-naphthalenesulfonic acid) is a competitive inhibitor targeting thyroxine binding globulin (TBG) (K_i=2.09×10 ⁶ M ^-1). ANS is used in radioimmunoassay by displacing bound triiodothyronine (T3) to improve detection sensitivity. ANS can block the protein binding site of T3 and release free T3 for antibody recognition. As a fluorescent probe, ANS can specifically bind to the hydrophobic region of proteins (such as membrane proteins) and monitor the dynamics of protein conformation through changes in fluorescent signals. It is widely used in biochemical research and antibacterial material development .

ANS

1 Publications Verification

ANSA; 8-Anilino-1-naphthalenesulfonic acid

Fluorescent Dyes

ANS (8-Anilino-1-naphthalenesulfonic acid) is a competitive inhibitor targeting thyroxine binding globulin (TBG) (K_i=2.09×10 ⁶ M ^-1). ANS is used in radioimmunoassay by displacing bound triiodothyronine (T3) to improve detection sensitivity. ANS can block the protein binding site of T3 and release free T3 for antibody recognition. As a fluorescent probe, ANS can specifically bind to the hydrophobic region of proteins (such as membrane proteins) and monitor the dynamics of protein conformation through changes in fluorescent signals. It is widely used in biochemical research and antibacterial material development .

HY-A0070AG

Liothyronine 1 Publications Verification Triiodothyronine; 3,3',5-Triiodo-L-thyronine; T3	Fluorescent Dyes
Liothyronine (Triiodothyronine) (GMP) is the Liothyronine (HY-A0070A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with K_is of 2.33 nM for hTRα and hTRβ, respectively .

HY-D0896A

ANS ammonium 1 Publications Verification NSC 1746 ammonium; Peri acid, phenyl- ammonium; Phenyl peri acid ammonium	Fluorescent Dyes
ANS ammonium is a potent antibacterial agent and a textile dye. ANS ammonium can be used as fluorescence probe. ANS ammonium blocks the binding of triiodothyronine to thyroxine binding globulin in radioimmunoassay of triiodothyronine .

HY-18341F

Biotin-(L-Thyroxine)	Fluorescent Dyes
Biotin-(L-Thyroxine) is the biotinylated L-Thyroxine (HY-18341). L-Thyroxine is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from Biotin-(L-Thyroxine) (T4) .

HY-D0896AR

ANS ammonium (Standard) NSC 1746 ammonium (Standard); Peri acid, phenyl- ammonium (Standard); Phenyl peri acid ammonium (Standard)	Fluorescent Dyes
ANS (ammonium) (Standard) is the analytical standard of ANS (ammonium). This product is intended for research and analytical applications. ANS ammonium is a potent antibacterial agent and a textile dye. ANS ammonium can be used as fluorescence probe. ANS ammonium blocks the binding of triiodothyronine to thyroxine binding globulin in radioimmunoassay of triiodothyronine .

Cat. No.	Product Name	Type

HY-107903

Thyroglobulin

Thyroglobulin from bovine

Biochemical Assay Reagents

Thyroglobulin is a 660 kDa, dimeric glycoprotein produced by the follicular cells of the thyroid and used entirely within the thyroid gland. Thyroglobulin acts as a substrate for the synthesis of the thyroid hormones thyroxine (T4) and triiodothyronine (T3), as well as the storage of the inactive forms of thyroid hormone and iodine within the follicular lumen of a thyroid follicle. Thyroglobulin activates Akt kinase activity in FRTL-5 thyroid cell .

HY-D0896

ANS

1 Publications Verification

ANSA; 8-Anilino-1-naphthalenesulfonic acid

Biochemical Assay Reagents

HY-A0070AG

Liothyronine 1 Publications Verification Triiodothyronine; 3,3',5-Triiodo-L-thyronine; T3	Biochemical Assay Reagents
Liothyronine (Triiodothyronine) (GMP) is the Liothyronine (HY-A0070A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with K_is of 2.33 nM for hTRα and hTRβ, respectively .

HY-D0896A

ANS ammonium 1 Publications Verification NSC 1746 ammonium; Peri acid, phenyl- ammonium; Phenyl peri acid ammonium	Biochemical Assay Reagents
ANS ammonium is a potent antibacterial agent and a textile dye. ANS ammonium can be used as fluorescence probe. ANS ammonium blocks the binding of triiodothyronine to thyroxine binding globulin in radioimmunoassay of triiodothyronine .

HY-W010669

L-Thyroxine sodium xhydrate Maximum Cited Publications 11 Publications Verification Sodium levothyroxine	Biochemical Assay Reagents
L-Thyroxine sodium xhydrate (Levothyroxine; T4) is a synthetic hormone in the treatment of hypothyroidism. DIO enzymes convert biologically active hormone (Triiodothyronine,T3) from L-Thyroxine (T4).

HY-D0896AR

ANS ammonium (Standard) NSC 1746 ammonium (Standard); Peri acid, phenyl- ammonium (Standard); Phenyl peri acid ammonium (Standard)	Biochemical Assay Reagents
ANS (ammonium) (Standard) is the analytical standard of ANS (ammonium). This product is intended for research and analytical applications. ANS ammonium is a potent antibacterial agent and a textile dye. ANS ammonium can be used as fluorescence probe. ANS ammonium blocks the binding of triiodothyronine to thyroxine binding globulin in radioimmunoassay of triiodothyronine .

HY-W010669R

L-Thyroxine sodium xhydrate (Standard) Sodium levothyroxine (Standard)	Biochemical Assay Reagents
L-Thyroxine sodium xhydrate (Standard) is the analytical standard of L-Thyroxine sodium xhydrate. This product is intended for research and analytical applications. L-Thyroxine sodium xhydrate (Levothyroxine; T4) is a synthetic hormone in the treatment of hypothyroidism. DIO enzymes convert biologically active hormone (Triiodothyronine,T3) from L-Thyroxine (T4).

Cat. No.	Product Name	Target	Research Area

HY-P3567

*(p-Iodo-Phe7)-ACTH (4-10)*	Melanocortin Receptor	Neurological Disease
(p-Iodo-Phe7)-ACTH (4-10) is a adrenocorticotrophic hormone (ACTH) derivative, which is produced and secreted by the anterior pituitary gland. (p-Iodo-Phe7)-ACTH (4-10) serves as a melanocortin (MC) receptor antagonist and inhibits α-melanocyte-stimulating hormone (α-MSH)-induced excessive grooming behavior in rats .

HY-P2434

AP102	Somatostatin Receptor	Neurological Disease Metabolic Disease Cancer
AP102 is a dual SSTR2/SSTR5-specific somatostatin analog (SSA). AP102 is a disulfide-bridged octapeptide SSA containing synthetic iodinated amino acids. AP102 binds with subnanomolar affinity to SSTR2 and SSTR5 (IC₅₀: 0.63 and 0.65 nM, respectively). AP102 does not bind to SSTR1 or SSTR3. AP102 can be used for acromegaly and neuroendocrine tumors research .

HY-P11578

CKGGRAKDC (linear)	Peptides	Metabolic Disease
CKGGRAKDC (linear) is an adipose tissue homing peptide. CKGGRAKDC (linear) binds to vasculature-enriched prohibitin in adipose tissue to enable selective tissue targeting. CKGGRAKDC (linear) can be used to selective delivery of cargos to adipose tissues .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-A0070A

Liothyronine Maximum Cited Publications 39 Publications Verification Triiodothyronine; 3,3',5-Triiodo-L-thyronine; T3	Monophenols Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Phenols Endocrine diseases Endogenous metabolite Disease Research Fields Endocrinology	Thyroid Hormone Receptor Endogenous Metabolite
Liothyronine is an active form of thyroid hormone. Liothyronine binds to thyroid hormone receptors TRα and TRβ with K_is of 2.33 and 2.29 nM for hTRα and hTRβ, respectively. Liothyronine also binds to PVR and blocks the interaction of TIGIT/PVR .

HY-A0070

Liothyronine sodium Maximum Cited Publications 39 Publications Verification Triiodothyronine sodium; 3,3',5-Triiodo-L-thyronine sodium; T3 sodium	Monophenols Classification of Application Fields Phenols Endogenous metabolite Disease Research Fields Endocrinology Source Classification Cancer	Thyroid Hormone Receptor Endogenous Metabolite
Liothyronine sodium is an active form of thyroid hormone. Liothyronine sodium is a potent thyroid hormone receptors TRα and TRβ agonist with K_is of 2.33 nM for hTRα and hTRβ, respectively .

HY-18341

L-Thyroxine 10+ Cited Publications Levothyroxine; T4	Monophenols Immune System Disorder Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Phenols Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields Endocrinology Source Classification	Thyroid Hormone Receptor Endogenous Metabolite
L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .

HY-18341B

L-Thyroxine sodium 10+ Cited Publications Levothyroxine sodium; T4 sodium	Natural Products Classification of Application Fields Endogenous metabolite Disease Research Fields Endocrinology Source Classification Cancer	Thyroid Hormone Receptor Endogenous Metabolite
L-Thyroxine sodium (Levothyroxine sodium) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .

HY-A0070B

Liothyronine sodium hydrate Maximum Cited Publications 39 Publications Verification Triiodothyronine sodium hydrate; 3,3',5-Triiodo-L-thyronine sodium hydrate; T3 sodium hydrate	Monophenols Classification of Application Fields Phenols Endogenous metabolite Disease Research Fields Endocrinology Source Classification Cancer	Thyroid Hormone Receptor Endogenous Metabolite
Liothyronine sodium hydrate is an active form of thyroid hormone. Liothyronine sodium hydrate is a potent thyroid hormone receptors TRα and TRβ agonist with K_is of 2.33 nM for hTRα and hTRβ, respectively .

HY-B1234

Octinoxate Octyl methoxycinnamate	Structural Classification Natural Products other families Classification of Application Fields Other Diseases Cosmetic Research Plants Disease Research Fields Source Classification	Environmental Pollutants Estrogen Receptor/ERR Androgen Receptor Cytochrome P450 Thyroid Hormone Receptor
Octinoxate (Octyl methoxycinnamate) is a thyroid hormone receptor agonist, reducing the levels of triiodothyronine (T3) and thyroxine (T4) and transcription levels of genes related to type II deiodinase (deio2) in Japanese Medaka. Octinoxate is commonly used as a safe ultraviolet (UV) filter used in the aquatic environment. Octinoxate inhibits CYP1A1 and CYP1B1 to regulate hyaluronan (HA) (HY-B0633A) metabolism in a PI3K pathway-dependent manner in human keratinocytes. Octinoxate also exhibits an anti-estrogenic and anti-androgenic effect in vitro and in vivo .

HY-A0070AR

Liothyronine (Standard) 30+ Cited Publications Triiodothyronine (Standard); 3,3',5-Triiodo-L-thyronine (Standard); T3 (Standard)	Monophenols Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Phenols Endocrine diseases Endogenous metabolite Disease Research Fields Endocrinology Source Classification	Thyroid Hormone Receptor Endogenous Metabolite Reference Standards
Liothyronine (Standard) is the analytical standard of Liothyronine. This product is intended for research and analytical applications. Liothyronine is an active form of thyroid hormone. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with K_is of 2.33 nM for hTRα and hTRβ, respectively .

HY-18341A

L-Thyroxine sodium salt pentahydrate 10+ Cited Publications Sodium levothyroxine pentahydrate	Natural Products Classification of Application Fields Endogenous metabolite Disease Research Fields Endocrinology Source Classification Cancer	Thyroid Hormone Receptor Endogenous Metabolite
L-Thyroxine sodium salt pentahydrate (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .

HY-126996

Triiodothyronine sulfate	Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Drug Metabolite Endogenous Metabolite
Triiodothyronine sulfate is the main metabolite of thyroid hormone triiodothyronine (T3). Triiodothyronine is an active form of thyroid hormone, which binds to β1 thyroid hormone receptor (TRβ1), and activates its activity .

HY-18341R

L-Thyroxine (Standard) Levothyroxine (Standard); T4 (Standard)	Structural Classification Monophenols Immune System Disorder Ketones, Aldehydes, Acids Disease markers Phenols Endocrine diseases Nervous System Disorder Endogenous metabolite Source Classification	Reference Standards Thyroid Hormone Receptor Endogenous Metabolite
L-Thyroxine (Standard) is the analytical standard of L-Thyroxine. This product is intended for research and analytical applications. L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .

HY-18341F

Biotin-(L-Thyroxine)	Natural Products Classification of Application Fields Endogenous metabolite Disease Research Fields Endocrinology Source Classification	Thyroid Hormone Receptor Endogenous Metabolite
Biotin-(L-Thyroxine) is the biotinylated L-Thyroxine (HY-18341). L-Thyroxine is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from Biotin-(L-Thyroxine) (T4) .

HY-A0070R

Liothyronine sodium (Standard) Triiodothyronine sodium (Standard); 3,3',5-Triiodo-L-thyronine sodium (Standard); T3 sodium (Standard)	Structural Classification Monophenols Phenols Endogenous metabolite Source Classification	Reference Standards Thyroid Hormone Receptor Endogenous Metabolite
Liothyronine (sodium) (Standard) is the analytical standard of Liothyronine (sodium). This product is intended for research and analytical applications. Liothyronine sodium is an active form of thyroid hormone. Liothyronine sodium is a potent thyroid hormone receptors TRα and TRβ agonist with K_is of 2.33 nM for hTRα and hTRβ, respectively .

HY-A0070C

Liothyronine hydrochloride Triiodothyronine hydrochloride; 3,3',5-Triiodo-L-thyronine hydrochloride; T3 hydrochloride	Monophenols Classification of Application Fields Phenols Endogenous metabolite Disease Research Fields Endocrinology Source Classification Cancer	Thyroid Hormone Receptor Endogenous Metabolite
Liothyronine hydrochloride is an active form of thyroid hormone. Liothyronine hydrochloride is a potent thyroid hormone receptors TRα and TRβ agonist with K_is of 2.33 nM for hTRα and hTRβ, respectively .

HY-18341BR

L-Thyroxine sodium (Standard) Levothyroxine sodium (Standard); T4 sodium (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Reference Standards Thyroid Hormone Receptor Endogenous Metabolite
L-Thyroxine (sodium) (Standard) is the analytical standard of L-Thyroxine (sodium). This product is intended for research and analytical applications. L-Thyroxine sodium (Levothyroxine sodium) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .

HY-135956

T3 Acyl glucuronide	Natural Products Monophenols Classification of Application Fields Phenols Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
T3 Acyl glucuronide, an endogenous metabolite, is the acyl glucuronide formation of triiodothyronine (T3) .

HY-18341AR

L-Thyroxine sodium salt pentahydrate (Standard) Sodium levothyroxine pentahydrate (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Thyroid Hormone Receptor Endogenous Metabolite Reference Standards
L-Thyroxine (sodium salt pentahydrate) (Standard) is the analytical standard of L-Thyroxine (sodium salt pentahydrate). This product is intended for research and analytical applications. L-Thyroxine sodium salt pentahydrate (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .

Cat. No.	Product Name	Chemical Structure

HY-18341S2

L-Thyroxine-13C6
L-Thyroxine- ¹³C₆ is the ¹³C labeled L-Thyroxine . L-Thyroxine (Levothyroxine;T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .

HY-141939S

Liothyronine-13C6 hydrochloride
Triiodothyronine- ¹³C₆ (hydrochloride) is the ¹³C labeled Triiodothyronine .

HY-A0070AS1

Liothyronine-13C9,15N
Liothyronine- ¹³C₉, ¹⁵N is the ¹³C and ¹⁵N labeled Liothyronine . Liothyronine is an active form of thyroid hormone. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with K_is of 2.33 nM for hTRα and hTRβ, respectively .

HY-A0070AS3

Liothyronine-d3
Liothyronine-d₃ is deuterated labeled Liothyronine (HY-A0070A). Liothyronine is an active form of thyroid hormone. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with K_is of 2.33 nM for hTRα and hTRβ, respectively .

HY-A0070AS2

Liothyronine-13C6-1
Liothyronine- ¹³C₆-1 is a ¹³C-labeled Liothyronine. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with K_is of 2.33 nM for hTRα and hTRβ, respectively .

HY-A0070AS5

Liothyronine-d4
Liothyronine-d₄ (Triiodothyronine-d₄) is the deuterium labeled Liothyronine (HY-A0070A). Liothyronine is an active form of thyroid hormone. Liothyronine binds to thyroid hormone receptors TRα and TRβ with vs of 2.33 and 2.29 nM for hTRα and hTRβ, respectively. Liothyronine also binds to PVR and blocks the interaction of TIGIT/PVR .

HY-W010696AS

Reverse T3-13C6 hydrochloride
Reverse T3- ¹³C₆ (hydrochloride) is the ¹³C labeled Reverse T3 .

HY-18341S1

Thyroxine hydrochloride-13C6
Thyroxine hydrochloride- ¹³C₆ is the ¹³C-labeled L-Thyroxine. L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .

HY-18341S4

L-Thyroxine-13C6-1
L-Thyroxine- ¹³C₆-1 (Levothyroxine- ¹³C₆-1; T4- ¹³C₆-1) is a ¹³C labeled L-Thyroxine (HY-18341). L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .

HY-W779345

Reverse T3-13C6
3,3',5'-Triiodo-L-thyronine- ¹³C₆ is ¹³C labeled 3,3',5'-Triiodo-L-thyronine .

HY-B1234S

Octinoxate-13C,d3

Octinoxate-13C,d3 is the deuterium labeled Octinoxate (HY-W245806). Octinoxate (Octyl methoxycinnamate) is a thyroid hormone receptor agonist, reducing the levels of triiodothyronine (T3) and thyroxine (T4) and transcription levels of genes related to type II deiodinase (deio2) in Japanese Medaka. Octinoxate is commonly used as a safe ultraviolet (UV) filter used in the aquatic environment. Octinoxate inhibits CYP1A1 and CYP1B1 to regulate hyaluronan (HA) (HY-B0633A) metabolism in a PI3K pathway-dependent manner in human keratinocytes. Octinoxate also exhibits an anti-estrogenic and anti-androgenic effect in vitro and in vivo .

HY-W713284

2-Ethylhexyl (E)-3-(4-(methoxy-d3)phenyl)acrylate

2-Ethylhexyl (E)-3-(4-(methoxy-d₃)phenyl)acrylate is the deuterium labeled Octinoxate (HY-B1234). Octinoxate (Octyl methoxycinnamate) is a thyroid hormone receptor agonist, reducing the levels of triiodothyronine (T3) and thyroxine (T4) and transcription levels of genes related to type II deiodinase (deio2) in Japanese Medaka. Octinoxate is commonly used as a safe ultraviolet (UV) filter used in the aquatic environment. Octinoxate inhibits CYP1A1 and CYP1B1 to regulate hyaluronan (HA) (HY-B0633A) metabolism in a PI3K pathway-dependent manner in human keratinocytes. Octinoxate also exhibits an anti-estrogenic and anti-androgenic effect in vitro and in vivo .

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-A0070AG

Liothyronine 1 Publications Verification Triiodothyronine; 3,3',5-Triiodo-L-thyronine; T3	Thyroid Hormone Receptor	Endocrinology Cancer
Liothyronine (Triiodothyronine) (GMP) is the Liothyronine (HY-A0070A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with K_is of 2.33 nM for hTRα and hTRβ, respectively .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Triiodothyronine

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

NaturalProducts

Isotope-Labeled Compounds

GMP Molecules

Natural
Products