ITYR-DBRMD
ITYR-DBRMD is a type III deiodinase (DIO3) inhibitor. ITYR-DBRMD shows antidepressant-like activity and reduces latency to feed in mice. ITYR-DBRMD can be used for the research of depression.
For research use only. We do not sell to patients.
- CAS No.: 1809339-61-4
- Formula: C13H7Br2I2NO5
- Molecular Weight:670.82
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
ITYR-DBRMD (Compouund 5) (0.5 μM; 48 h) reduces cell viability in OVCAR3 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:OVCAR3 cells
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Concentration:0.5 μM
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Incubation Time:48 h
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Result:Reduced cell numbers by microscopy.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:BALB/c (male, 8 weeks old)[1]
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Dosage:5 mg/kg
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Administration:i.c.v.; continuous infusion via osmotic minipump
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Result:Reduced the latency to feed in the novelty suppressed feeding test.
Chemical Information
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CAS No. 1809339-61-4
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Molecular Weight 670.82
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Formula C13H7Br2I2NO5
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SMILES
O=C(C(CC1=CC(I)=C(C(I)=C1)O)N2C(C(Br)=C(C2=O)Br)=O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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