32 Results for "

calf thymus

" in MedChemExpress (MCE) Product Catalog:
Products (32)

32 Results for "calf thymus" in MCE Product Catalog:

7
7 Publications Verification
Cat. No.: HY-109517
CAS No.: 91080-16-9
Synonyms: DNA from calf thymus, Thymonucleic acid
Calf thymus DNA (DNA from calf thymus) is high quality double-stranded template DNA isolated from the thymus of male and female calves. Calf thymus DNA can be used for the research of the interaction between DNA and agents .
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7
7 Publications Verification
Cat. No.: HY-153118
CAS No.: 73049-39-5
Synonyms: ctDNA sodium, Type I, fibers; DNA sodium, from calf thymus, Type I, fibers; Thymonucleic acid sodium, Type I, fibers
Research Areas:  

Others Cancer

Deoxyribonucleic acid sodium, from calf thymus, Type I, fibers is the sodium salts form of Calf thymus DNA (HY-109517). Calf thymus DNA is a double-stranded template DNA isolated from calf thymus. It can be used to study the interaction between DNA and DNA binding agents, as well as the structure and function of DNA, for DNA quantification and used as a substrate for DNA polymerase analysis, etc​ .
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2
2 Cited Publications
Cat. No.: HY-121309
CAS No.: 24385-10-2
Synonyms: Adriamycin aglycone; Adriamycinone
Doxorubicinone (Adriamycin aglycone) is the aglycone of the antibiotic Doxorubicin (HY-15142A), i.e., its sugar-free parent nucleus structure. Doxorubicinone does not induce DNA damage or bind to RelA, but still downregulates the expression of pro-inflammatory cytokines (such as TNF, IL-12, etc.) regulated by the NF-κB pathway. Doxorubicinone can be used in sepsis-related research .
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1
1 Cited Publications
Cat. No.: HY-NP155
CAS No.: 9064-47-5
Histone (calf thymus) is a histone found in the deoxyribonucleoprotein of calf thymus and can be obtained by acid extraction technique .
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Cat. No.: HY-13718
CAS No.: 38101-59-6
Purity:  98.97%
Synonyms: H-Glu-Trp-OH; L-Glutamyl-L-tryptophan
Oglufanide (H-Glu-Trp-OH) is a dipeptide immunomodulator isolated from calf thymus. Oglufanide inhibits vascular endothelial growth factor (VEGF). Oglufanide can stimulate the immune response to hepatitic C virus (HCV) and intracellular bacterial infections. Oglufanide shows antitumor and anti-angiogenesis activities .
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Cat. No.: HY-W020955
CAS No.: 14243-64-2
Synonyms: Chloro(triphenylphosphine)gold(I)
Triphenylphosphinechlorogold (Chloro(triphenylphosphine)gold(I)) is a gold complex, Apoptosis inducer, and catalyst. Triphenylphosphinechlorogold exhibits high LOX inhibitory activity. Triphenylphosphinechlorogold induces cell cycle arrest and apoptosis. Triphenylphosphinechlorogold catalyzes the peroxidation of linoleic acid. A weak interaction exists between Triphenylphosphinechlorogold and DNA. Triphenylphosphinechlorogold displays antiproliferative activity against breast cancer cells .
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Cat. No.: HY-137694B
Purity:  99.94%
ddTTP trisodium solution (100 mM) is a DNA polymerase γ inhibitor, with Ki values of 0.05 μM and 0.4 μM against bovine testicular DNA polymerase γ. ddTTP trisodium solution (100 mM) can be incorporated into DNA to cause termination of the extended DNA strand. ddTTP trisodium solution (100 mM) can be used in the research of HIV infection .
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Cat. No.: HY-NP155A
CAS No.: 1523001-32-2
Histone H1 (calf thymus) is a linker histone subtype found in the deoxyribonucleoprotein of calf thymus and can be obtained by separation and purification from total calf thymus histones .
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Cat. No.: HY-N12851
CAS No.: 2492-43-5
Synonyms: (E)-4-Oxo-2-hexenal
4-OHE ((E)-4-Oxo-2-hexenal) is a mutagen formed by omega-3 lipid peroxidation. 4-OHE reacts with deoxyguanosine, deoxycytidine and 5-methyldeoxycytidine to form covalent adducts. 4-OHE induces apoptosis and exhibits genotoxicity. 4-OHE inhibits the growth of Gram-positive and Gram-negative bacteria, which correlates with its electrophilic reactivity towards nucleophilic biomolecules. 4-OHE is a chemical defense component of Dolycoris baccarum (sloe bug), and acts as a deterrent and toxin against insect predators .
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Cat. No.: HY-W339331
CAS No.: 272451-65-7
Synonyms: NNI-0001
Flubendiamide (NNI-0001) is an orally active phthalic diamide insecticide that acts by targeting insect ryanodine receptors (RyRs), causing insect muscle dysfunction, paralysis and death. Flubendiamide disrupts molting, metamorphosis and reproductive processes, induces oxidative stress by increasing the levels of ROS/RNS, MDA and 8OHdG and decreasing the levels of SOD, CAT and GST, activates the CncC/Maf apoptosis pathway, impairs calcium homeostasis, promotes adipogenesis, increases triglyceride accumulation, and upregulates the expression of regulatory factors for adipocyte differentiation and adipogenesis .
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Cat. No.: HY-146350
CAS No.: 2414906-32-2
Research Areas:  

Cancer

TrxR-IN-4 is a thioredoxin reductase (TrxR) inhibitor with a rat IC50 of 0.37 μM. TrxR-IN-4 inhibits TrxR activity, elevates reactive oxygen species (ROS) and induces apoptosis. TrxR-IN-4 mediates endoplasmic reticulum stress and induces mitochondrial dysfunction. TrxR-IN-4 can be used for the research of hepatocellular carcinoma .
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Cat. No.: HY-137673
CAS No.: 6697-37-6
Target:  

NADH Dehydrogenase

Research Areas:  

Others

2'-Deoxy-NAD+ is a noncompetitive NAD+ inhibitor with a Ki of 32 μM. 2'-Deoxy-NAD+ can be utilized as a substrate to study the ADP-ribosyl transfer reaction .
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Cat. No.: HY-W016840
CAS No.: 14510-06-6
8-Hydroxyquinoline-2-carbaldehyde is a quinoline derivative with the functions of DNA intercalation, hydroxyl radical scavenging and superoxide radical scavenging. 8-Hydroxyquinoline-2-carbaldehyde serves as a precursor for synthesizing Schiff base ligands with DNA intercalation activity and antioxidant properties. 8-Hydroxyquinoline-2-carbaldehyde can be used in relevant research across multiple fields including materials science and biomedicine .
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Cat. No.: HY-121782
CAS No.: 111279-49-3
Research Areas:  

Infection

A 65281 is a potent DNA gyrase inhibitor with an IC50 value of 0.1 µg/mL. A 65281 induces DNA breakage mediated by calf thymus topoisomerase II. A 65281 inhibits P4 DNA unknotting with an IC50 value of 8 µg/mL .
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Cat. No.: HY-N16549
CAS No.: 86631-41-6
Synonyms: 3-O-Galloylprocyanidin B3
Procyanidin B3-3-O-gallate (3-O-Galloylprocyanidin B3) is a selective mammalian DNA polymerase α inhibitor, with a calf DNA polymerase α IC50 of 0.26 μM. Procyanidin B3-3-O-gallate scavenges DPPH radicals. Procyanidin B3-3-O-gallate can be used for research on oxidative stress and inflammatory diseases[1].
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Cat. No.: HY-135181
CAS No.: 28008-54-0
Target:  

Antibiotic Bacterial

Research Areas:  

Inflammation/Immunology

Daunosamnyl-daunorubic, an antibiotic, can bind calf thymus DNA .
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Cat. No.: HY-120747
CAS No.: 135906-72-8
Research Areas:  

Infection

A-65282 is an antibacterial agent. A-65282 inhibits P4 DNA unknotting with an IC50 value of 8 µg/mL. A 65281 induces DNA breakage mediated by calf thymus topoisomerase II .
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Cat. No.: HY-13718A
CAS No.: 237068-57-4
Synonyms: H-Glu-Trp-OH disodium; L-Glutamyl-L-tryptophan disodium
Oglufanide (H-Glu-Trp-OH) disodium is a dipeptide immunomodulator isolated from calf thymus. Oglufanide disodium inhibits vascular endothelial growth factor (VEGF). Oglufanide disodium can stimulate the immune response to hepatitic C virus (HCV) and intracellular bacterial infections. Oglufanide disodium shows antitumor and anti-angiogenesis activities .
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Cat. No.: HY-137673A
CAS No.: 1514900-83-4
Target:  

NADH Dehydrogenase

Research Areas:  

Others

2'-Deoxy-NAD+ sodium is a noncompetitive NAD+ inhibitor with a Ki of 32 μM. 2'-Deoxy-NAD+ sodium can be utilized as a substrate to study the ADP-ribosyl transfer reaction .
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Cat. No.: HY-144255
Research Areas:  

Infection

Antibacterial agent 70 is an antibacterial agent that interacts with DNA, with a MIC value of 0.5 μg/mL against K. pneumonia and A. baumanii. Antibacterial agent 70 exhibits rapid bactericidal activity, low cytotoxicity to mammalian cells, and low tendency to induce drug resistance. Antibacterial agent 70 intercalates into DNA, disrupts bacterial membrane integrity, increases intracellular ROS production, reduces GSH activity, regulates membrane depolarization, enhances outer membrane permeability, and induces inner membrane damage. Antibacterial agent 70 can be used in studies related to multidrug-resistant bacterial infections and infections caused by drug-resistant Gram-negative pathogens .
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