Deoxyribonucleic acid sodium, from calf thymus, Type I, fibers
Based on 8 publication(s) in Google Scholar
Deoxyribonucleic acid sodium, from calf thymus, Type I, fibers is the sodium salts form of Calf thymus DNA (HY-109517). Calf thymus DNA is a double-stranded template DNA isolated from calf thymus. It can be used to study the interaction between DNA and DNA binding agents, as well as the structure and function of DNA, for DNA quantification and used as a substrate for DNA polymerase analysis, etc.
For research use only. We do not sell to patients.
- CAS No.: 73049-39-5
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications Citing Use of MedChemExpress (MCE) Deoxyribonucleic acid sodium, from calf thymus, Type I, fibers
More- Nat Commun. 2024 Dec 5;15(1):10599. [Abstract]
- J Med Chem. 2026 Aug 13;69(15):18705-18722.
- J Med Chem. 2026 Jun 25;69(12):14492-14512. [Abstract]
- J Ethnopharmacol. 2025 Feb 11:341:119304. [Abstract]
- Pharm Res. 2026 May 27. [Abstract]
- J Transl Autoimmun. 2026 Jan 12:12:100349. [Abstract]
- chemRxiv. 2025 Dec 22.
- Biomed Pharmacother. 2024 Jun:175:116794. [Abstract]
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ELISA
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ELISA
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ELISA
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Bio/Physico-chemical Assay
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Bio/Physico-chemical Assay
Biological Activity
Description
In Vitro
Note: To reduce DNA shearing, sonication or agitation should not be used. It's recommended to shake gently overnight at 0-4°C to completely dissolve the DNA.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 73049-39-5
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Appearance Solid
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Color White to off-white
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SMILES
[Calf thymus DNA (sodium)]
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Synonyms
ctDNA sodium, Type I, fibers; DNA sodium, from calf thymus, Type I, fibers; Thymonucleic acid sodium, Type I, fibers
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (8)
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Journal Impact Factor
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Most Recent
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Nat Commun
Aberrant METTL1-mediated tRNA m7G modification alters B-cell responses in systemic autoimmunity in humans and mice. [Abstract]2024 Dec 5;15(1):10599. PMID: 39638793 -
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J Med Chem
Structure-Guided Discovery of Potent, Selective, and Orally Bioavailable Werner Syndrome RecQ Helicase Inhibitors for the Treatment of Microsatellite Instability-High Tumors. [Abstract]2026 Jun 25;69(12):14492-14512. PMID: 42234810 -
J Ethnopharmacol
Investigating the mechanism of Tongfeng Qingxiao Formula for improving gouty arthritis based on the neutrophil extracellular trapping network. [Abstract]2025 Feb 11:341:119304. PMID: 39736350 -
Pharm Res
Rational Design, Optimization and Bioinformatic Analysis of Anti-PD-L1 Peptide Conjugated Mocetinostat Prodrug Nanoparticles for Predictive Cancer Chemoimmunotherapeutic Efficacy. [Abstract]2026 May 27. PMID: 42204129 -
J Transl Autoimmun
Liraglutide prevents lupus-associated diffuse alveolar hemorrhage via inhibiting lymphocyte infiltration and promoting macrophage M2 polarization. [Abstract]2026 Jan 12:12:100349. PMID: 41626528 -
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Biomed Pharmacother
Ginsenoside Rb1 mitigates acute catecholamine surge-induced myocardial injuries in part by suppressing STING-mediated macrophage activation. [Abstract]2024 Jun:175:116794. PMID: 38776673
Deoxyribonucleic acid sodium, from calf thymus, Type I, fibers purchased from MedChemExpress. Usage Cited in: Biomed Pharmacother. 2024 Jun:175:116794. [Abstract]
RAW264.7 cells were treated with either vehicle or Rb1 at 50, 100, 200 and 400 μM in the presence or absence of 2 μg/ml ctDNA (Calf thymus DNA) stimulation. The levels of TNFα, IL6 and CCL2 in the culture supernatants collected 3 h post ctDNA stimulation were analyzed by ELISA.
Deoxyribonucleic acid sodium, from calf thymus, Type I, fibers purchased from MedChemExpress. Usage Cited in: Biomed Pharmacother. 2024 Jun:175:116794. [Abstract]
The supernatants were collected 6 h post ctDNA (Calf thymus DNA) stimulation and the production of TNFα, IL6, CCL2 and IFN-β was quantified by ELISA.
Deoxyribonucleic acid sodium, from calf thymus, Type I, fibers purchased from MedChemExpress. Usage Cited in: Biomed Pharmacother. 2024 Jun:175:116794. [Abstract]
The supernatants collected 12 h post ctDNA (Calf thymus DNA) stimulation were analyzed by ELISA to quantify the level of TNFα, IL6, CCL2 and IFN-β.
Deoxyribonucleic acid sodium, from calf thymus, Type I, fibers purchased from MedChemExpress. Usage Cited in: Biomed Pharmacother. 2024 Jun:175:116794. [Abstract]
Volcano plot of DEGs from the ctDNA (Calf thymus DNA) vs Ctrl. C. Line charts categorizing DEGs (ctDNA vs Ctrl) using Mfuzz clustering.
Deoxyribonucleic acid sodium, from calf thymus, Type I, fibers purchased from MedChemExpress. Usage Cited in: Biomed Pharmacother. 2024 Jun:175:116794. [Abstract]
Enriched pathways revealed by GSEA (Rb1 vs ctDNA (Calf thymus DNA)). Ctrl, vehicle-treated RAW264.7 cells; ctDNA, vehicle-treated ctDNA-stimulated RAW264.7 cells; Rb1, Rb1-treated ctDNA-stimulated RAW264.7 cells; NES normalized enrichment score.
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Li HJ, Brand B, Rotter A. Thermal denaturation of calf thymus DNA: existence of a GC-richer fraction. Nucleic Acids Res. 1974 Feb;1(2):257-65. [Content Brief]
[2]. Akhter F, et al. Bio-physical characterization of ribose induced glycation: a mechanistic study on DNA perturbations. Int J Biol Macromol. 2013 Jul;58:206-10. [Content Brief]
[3]. Liu F, et al. Cytotoxicity of Aconitum alkaloid and its interaction with calf thymus DNA by multi-spectroscopic techniques. Sci Rep. 2017 Nov 6;7(1):14509. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)