Search Result
Results for "
hydrazide
" in MedChemExpress (MCE) Product Catalog:
5
Biochemical Assay Reagents
4
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-134722
-
|
PROTAC Linkers
|
Cancer
|
Hydrazide-PEG4-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-D1564
-
-
-
- HY-D1880
-
|
Fluorescent Dye
|
Others
|
Sulfo-Cy5 hydrazide is a fluorescent dye containing a hydrazide functionality (Ex/Em=646/662 nm) .
|
-
-
- HY-D1882
-
|
Fluorescent Dye
|
Others
|
Cy5.5 hydrazide is a fluorescent dye containing a hydrazide functionality. Cy5.5 hydrazide can be used to label aldehydes and ketones .
|
-
-
- HY-D1324
-
|
Fluorescent Dye
|
Others
|
Cyanine5.5 hydrazide, an analog of Cyanine5.5 fluorophore, is a near-infrared (NIR) fluorescent dye. Cyanine5.5 hydrazide is used for labeling of biomolecules through the condensation between the hydrazide groups and the carbonyl groups. (λex=684 nm, λem=710 nm) .
|
-
-
- HY-125501
-
Biotin-(AC5)2-hydrazide
|
Biochemical Assay Reagents
|
Others
|
Biotin-XX hydrazide (Biotin-(AC5)2-hydrazide) is a carbonyl-reactive biotinylation reagent which contains two aminohexanoic acid spacers. Biotin-XX hydrazide has higher efficiency of avidin-binding .
|
-
-
- HY-137100
-
Cyanine5 hydrazide
|
Fluorescent Dye
|
Others
|
Cy 5 hydrazide (Cyanine5 hydrazide) is a fluorescent dye for aldehydes and ketones. Cy 5 hydrazide can be used for labeling proteins .
|
-
-
- HY-59354S
-
|
DNA/RNA Synthesis
|
Cancer
|
Maleic hydrazide-d2 is the deuterium labeled Maleic hydrazide[1]. Maleic hydrazide is extensively used as a systemic plant growth regulator and as a herbicide. Maleic hydrazide acts as an inhibitor of the synthesis of nucleic acids and proteins[2][3].
|
-
-
- HY-59354R
-
|
DNA/RNA Synthesis
|
Cancer
|
Maleic hydrazide (Standard) is the analytical standard of Maleic hydrazide. This product is intended for research and analytical applications. Maleic hydrazide is extensively used as a systemic plant growth regulator and as a herbicide. Maleic hydrazide acts as an inhibitor of the synthesis of nucleic acids and proteins .
|
-
-
- HY-59354
-
|
DNA/RNA Synthesis
|
Cancer
|
Maleic hydrazide is extensively used as a systemic plant growth regulator and as a herbicide. Maleic hydrazide acts as an inhibitor of the synthesis of nucleic acids and proteins .
|
-
-
- HY-151644
-
|
Fluorescent Dye
|
Others
|
Fluorescein hydrazide is a colorimetric probe formed by the reaction of dihydrazine adipate with fluorescein isothiocyanate. Fluorescein hydrazide can be used to label aldehyde and ketone groups .
|
-
-
- HY-101885
-
Biotinamidocaproyl hydrazide; BACH; (+)-Biotinamidohexanoic Acid hydrazide; Biotin Aminocaproyl hydrazide
|
Biochemical Assay Reagents
|
Others
|
Biotin LC hydrazide is a long chain protein modification reagent, which can transform periodate-oxidized glycoproteins.
|
-
-
- HY-151774
-
|
Fluorescent Dye
|
Others
|
TAMRA hydrazide (6-isomer) is a click chemistry reagent that can be coupled to carbonyl compounds. The dye hydrazide in TAMRA hydrazide (6-isomer) labels carbonyl compounds such as aldehydes and ketones. TAMRA in TAMRA hydrazide (6-isomer) is a xanthene red fluorophore that reacts with terminal alkynes .
|
-
-
- HY-D1586
-
|
Fluorescent Dye
|
Others
|
Cyanine5 Boc-hydrazide (chloride) is a cyanine5-labeled and Boc-protected hydrazide fluorescent dye.
|
-
-
- HY-D1667
-
|
Fluorescent Dye
|
Others
|
BDP 558/568 hydrazide is a carbonyl reactive hydrazide derivative of BDP 558/568 (BDP 558/568: Ex=558 nm, Em=568 nm). BDP 558/568 hydrazide can be used for the labeling of aldehydes or ketones.
|
-
-
- HY-151690
-
|
Fluorescent Dye
|
Others
|
FAM hydrazide, 6-isomer is a hydrazide derivative of fluorescein (FAM). FAM is a xanthene dye, a parent of fluorescein dye series. FAM hydrazide, 6-isomer can be used for the labeling of carbonyl compounds, aldehydes, and ketones .
|
-
-
- HY-132264
-
|
Fluorescent Dye
|
Others
|
FAM hydrazide, 6-isomer hydrochloride is a hydrazide derivative of fluorescein (FAM). FAM is a xanthene dye, a parent of fluorescein dye series. FAM hydrazide, 6-isomer hydrochloride can be used for the labeling of carbonyl compounds, aldehydes, and ketones .
|
-
-
- HY-141402
-
|
PROTAC Linkers
|
Cancer
|
m-PEG4-Hydrazide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
-
- HY-141403
-
|
PROTAC Linkers
|
Cancer
|
m-PEG37-hydrazide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
-
- HY-140933
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG12-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-133344
-
|
PROTAC Linkers
|
Cancer
|
m-PEG3-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-135922
-
|
PROTAC Linkers
|
Cancer
|
m-PEG6-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-135921
-
|
PROTAC Linkers
|
Cancer
|
m-PEG5-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-130891
-
|
PROTAC Linkers
|
Cancer
|
(+)-Biotin-PEG6-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-130892
-
|
PROTAC Linkers
|
Cancer
|
(+)-Biotin-PEG2-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-133345
-
|
PROTAC Linkers
|
Cancer
|
m-PEG7-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-133347
-
|
PROTAC Linkers
|
Cancer
|
m-PEG11-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-133348
-
|
PROTAC Linkers
|
Cancer
|
m-PEG12-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-133349
-
|
PROTAC Linkers
|
Cancer
|
m-PEG13-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-133350
-
|
PROTAC Linkers
|
Cancer
|
m-PEG17-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-133351
-
|
PROTAC Linkers
|
Cancer
|
m-PEG25-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-133346
-
|
PROTAC Linkers
|
Cancer
|
m-PEG9-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-W111879S
-
-
-
- HY-133427
-
|
ADC Linker
|
Cancer
|
Propargyl-PEG4-hydrazide is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG4-hydrazide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
-
- HY-140932
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG4-hydrazide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-100215
-
-
-
- HY-W142000
-
-
-
- HY-D2251
-
-
-
- HY-140814
-
|
PROTAC Linkers
|
Cancer
|
Azido-PEG4-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
-
- HY-140815
-
|
PROTAC Linkers
|
Cancer
|
Azido-PEG8-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
-
- HY-133438
-
|
PROTAC Linkers
|
Cancer
|
BCN-PEG4-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . BCN-PEG4-hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
-
- HY-140932A
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG4-hydrazide (TFA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-W012617
-
Nicotinic acid hydrazide
|
Others
|
Others
|
Nicotinohydrazide (Nicotinic acid hydrazide) is a small molecular compound .
|
-
-
- HY-123645
-
|
Fluorescent Dye
|
Others
|
Rhodamine B hydrazide is a good probe for sulfite, with colorless and non-fluorescent properties. While the emission is related to the concentration of sulfite (5-800 ng/mL; detection limit=1.4 ng/mL (3σ)). Sulfite reduces dissolved oxygen to yield superoxide radicals, which binds to Rhodamine B hydrazide to form Rhodamine B. Rhodamine B hydrazide gives Rhodamine B-like fluorescence in the presence of sulfite, which is enhanced by Tween 80 surfactant micelles. Rhodamine B hydrazide has an absorption maximum at 554 nm and a fluorescence emission maximum at 574 nm .
|
-
-
- HY-136097
-
|
ADC Linker
|
Cancer
|
Maleimide-PEG2-hydrazide (TFA) is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
-
- HY-130886
-
|
PROTAC Linkers
|
Cancer
|
N3-PEG12-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N3-PEG12-Hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
-
- HY-133320
-
|
PROTAC Linkers
|
Cancer
|
N3-PEG16-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N3-PEG16-Hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
-
- HY-133321
-
|
PROTAC Linkers
|
Cancer
|
N3-PEG24-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N3-PEG24-Hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
-
- HY-133339
-
|
PROTAC Linkers
|
Cancer
|
H2N-PEG4-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-133340
-
|
PROTAC Linkers
|
Cancer
|
H2N-PEG5-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133341
-
|
PROTAC Linkers
|
Cancer
|
H2N-PEG6-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133342
-
|
PROTAC Linkers
|
Cancer
|
H2N-PEG8-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133343
-
|
PROTAC Linkers
|
Cancer
|
H2N-PEG12-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-147168
-
|
Others
|
Metabolic Disease
|
Biocytin hydrazide is a selective label for sialic acids, galactose, and other sugars in glycoconjugates using avidin-biotin technology .
|
-
- HY-114351
-
|
Fluorescent Dye
|
Others
|
BODIPY FL Hydrazide is a green-fluorescent dye, BODIPY FL Hydrazide is reactive with aldehyde/ketone on polysaccharides and glycoproteins, yielding a reversible Schiff base product that can be transformed to a stable linkage using a reducing agent like sodium borohydride or sodium cyanoborohydride. (λex=495 nm, λem=516 nm) .
|
-
- HY-D1619
-
|
Fluorescent Dye
|
Others
|
Cyanine3 hydrazide dichloride is a carbonyl reactive dye. Cyanine3 hydrazide dichloride allows the labelling of various carbonyl-containing molecules such as antibodies and other glycoproteins after oxidation by periodate, proteins or reducing sugars after oxidative stress or deamination .
|
-
- HY-D1599
-
R6GH
|
Fluorescent Dye
|
Others
|
Rhodamine 6G hydrazide (R6GH) is a fluorescent dye. Rhodamine 6G hydrazide can be used in selective colorimetric and fluorescent sensing .
|
-
- HY-D1861
-
|
Fluorescent Dye
|
Others
|
Sulfo-Cy3 hydrazide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative with hydrazine functionality. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The hydrazide group of Sulfo-Cy3 hydrazide can form hydrazinone coupling with molecules containing aldehydes or ketones to form covalent bonds. Therefore, Cy3 azide plus can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-130560
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG3-propionic hydrazide is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.
|
-
- HY-140223
-
|
PROTAC Linkers
|
Cancer
|
Amino-PEG4-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140224
-
|
PROTAC Linkers
|
Cancer
|
Amino-PEG8-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133410A
-
|
PROTAC Linkers
|
Cancer
|
Mal-C2-cyclohexylcarboxyl-hydrazide hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140816
-
|
PROTAC Linkers
|
Cancer
|
Azido-PEG2-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG2-hydrazide-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140817
-
|
PROTAC Linkers
|
Cancer
|
Azido-PEG4-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-hydrazide-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-D2151
-
|
Fluorescent Dye
|
Others
|
AF 430 hydrazide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 430 nm and an emission wavelength of 542 nm. AF 430 hydrazide can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) via the Azide group and molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups. To achieve specific coupling of dye labels and biomolecules.
|
-
- HY-133410
-
|
PROTAC Linkers
|
Cancer
|
Mal-C2-cyclohexylcarboxyl-hydrazide (TFA) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140222
-
|
PROTAC Linkers
|
Cancer
|
Amino-PEG2-C2-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-D1601
-
|
Fluorescent Dye
|
Others
|
N-Aminofluorescein is a fluorescein hydrazide with spiro form, a highly selective and sensitive fluorescence probe for Cu 2+. N-Aminofluorescein has no selective fluorescence response to other common metal ions, can be used for direct detection of Cu 2+ in biological systems with λex/em=495/516 nm .
|
-
- HY-B0329
-
INH; Isonicotinic acid hydrazide; Isonicotinic hydrazide
|
Bacterial
Autophagy
Mitophagy
Antibiotic
|
Infection
|
Isoniazid (INH) is a proagent and must be activated by a bacterial catalase-peroxidase enzyme KatG. Isoniazid is bactericidal to rapidly dividing mycobacteria and has anti-tuberculostatic activity .
|
-
- HY-128941
-
|
Drug-Linker Conjugates for ADC
|
Cancer
|
CCK2R Ligand-Linker Conjugates 1 is a ligand-linker conjugate, which conjugates to the cytotoxic antimicrotubule agents Desacetyl Vinblastine Hydrazide (DAVBH) and Tubulysin B Hydrazide (TubBH) via a hydrophilic peptide linker .
|
-
- HY-D2013
-
|
Fluorescent Dye
|
Others
|
ATTO 488 hydrazid is a hydrazide derivative of ATTO 488 with excitation/emission maxima at 500/520 nm.
|
-
- HY-D2053
-
|
Fluorescent Dye
|
Others
|
ATTO 532 hydrazid is a hydrazide derivative of ATTO 532 with maximum excitation/emission wavelengths: 532/552 nm.
|
-
- HY-D2011
-
|
Fluorescent Dye
|
Others
|
ATTO 565 hydrazid is a hydrazide derivative of ATTO 565 with maximum excitation/emission wavelengths: 564/590 nm.
|
-
- HY-D2037
-
|
Fluorescent Dye
|
Others
|
ATTO 550 hydrazid is a hydrazide derivative of ATTO 550 with maximum excitation/emission wavelengths: 554/576 nm.
|
-
- HY-D2034
-
|
Fluorescent Dye
|
Others
|
ATTO 514 hydrazid is a hydrazide derivative of ATTO 514 with maximum excitation/emission wavelengths: 511/531 nm.
|
-
- HY-144668
-
|
Influenza Virus
|
Infection
|
RdRP-IN-4 (compound 11q), an aryl benzoyl hydrazide analog, is an orally active influenza A virus RNA-dependent RNA polymerase (RdRp) inhibitor by interacting with the PB1 subunit. RdRP-IN-4 exhibits potent inhibitory activity against the avian H5N1 flu strain with an EC50 of 18 nM in MDCK cells. RdRP-IN-4 displays excellent potency against the the H1N1 (A/PR/8/34) Flu A strain and Flu B strain (B/Lee/1940) with EC50 values of 53 nM and 20 nM, respectively. RdRP-IN-4 significantly inhibits the expression level of viral nucleoprotein (NP) in a dose-dependent manner. RdRP-IN-4 exhibits significant antiviral activity in infected mice .
|
-
- HY-154993
-
|
Others
|
Infection
|
Gamma-Glutamyl Transferase-IN-1 (compound 4de) is a β-carboline 1-hydrazide inhibitor with antifungal and antibacterial activities, targeting to glutamyltransferase. Gamma-Glutamyl Transferase-IN-1 acts function by resulting the accumulation of reactive oxygen species, destruction of cell membranes, and dysregulation of histone acetylation .
|
-
- HY-154996
-
|
Others
|
Infection
|
Gamma-Glutamyl Transferase-IN-2 (compound 4dq) is a β-carboline 1-hydrazide inhibitor with antifungal and antibacterial activities, targeting to glutamyltransferase. Gamma-Glutamyl Transferase-IN-2 acts function by resulting the accumulation of reactive oxygen species, destruction of cell membranes, and dysregulation of histone acetylation .
|
-
- HY-B0994
-
Cyanoacetic hydrazide; 2-Cyanoacetohydrazide
|
Bacterial
|
Infection
|
Cyanoacetohydrazide is an anti-TB drug.
|
-
- HY-B1048
-
Paraniazide; Pasiniazide; Isonicotinic acid hydrazide p-aminosalicylate
|
Bacterial
|
Inflammation/Immunology
|
Pasiniazid is an anti-TB and anti-leprosy drug, used to treat various types of TB and leprosy.
|
-
- HY-B0880
-
p-Aminobenzohydrazide; p-Aminobenzoic acid hydrazide
|
|
|
4-Aminobenzohydrazide is an irreversible MPO myeloperoxidase inhibitor with an IC50 of 0.3 µM . It is used for the research of subacute stroke .
|
-
- HY-114306
-
|
Antifolate
|
Cancer
|
EC0489, a conjugate of folic acid and desacetyl vinblastine hydrazide, is a high-affinity ligand for the folate receptor (FR). Refractory or metastatic Tumor . Small molecule-agent conjugate (SMDC) .
|
-
- HY-B0329S
-
INH-d4; Isonicotinic acid hydrazide-d4; Isonicotinic hydrazide-d4
|
Bacterial
Autophagy
Mitophagy
Antibiotic
|
Infection
|
Isoniazid-d4 is the deuterium labeled Isoniazid. Isoniazid (INH) is a proagent and must be activated by a bacterial catalase-peroxidase enzyme KatG. Isoniazid is bactericidal to rapidly dividing mycobacteria and has anti-tuberculostatic activity[1][2][3][4].
|
-
- HY-148453
-
|
Others
|
Cancer
|
Antiproliferative agent-16 is an indolyl hydrazide-hydrazone compound with anticancer activity. Antiproliferative agent-16 exhibits specificity toward breast cancer cells (IC50 of 6.94 μM for MCF-7 cells) .
|
-
- HY-155769
-
|
Fungal
|
Infection
|
Antimicrobial agent-24 (compound E8) is a hydrazide compound with excellent and broad-spectrum fungicidal activities. Antimicrobial agent-24 affects the normal function of the plasma membrane, further generating changes in the morphology and subcellular structure of mycelia .
|
-
- HY-B1703
-
|
Bacterial
Antibiotic
|
Infection
|
Nifursol is a potent and orally active veterinary antibiotic for the prevention of histomoniasis. Nifursol rapidly metabolizes to form the metabolic marker 3,5-dinitrosalicyclic acid hydrazide (DNSAH) which can persist for a long time. Nifursol is widely used for the research of Escherichia Gastroenteropathy in poultry, fowl and aquatic animal .
|
-
- HY-B1703S
-
|
Bacterial
Antibiotic
|
Infection
|
Nifursol- 13C6 is the 13C6 labeled Nifursol. Nifursol is a potent and orally active veterinary antibiotic for the prevention of histomoniasis. Nifursol rapidly metabolizes to form the metabolic marker 3,5-dinitrosalicyclic acid hydrazide (DNSAH) which can persist for a long time. Nifursol is widely used for the research of Escherichia Gastroenteropathy in poultry, fowl and aquatic animal.
|
-
- HY-155907
-
DSPE-PEG-NH2, MW 5000 ammonium
|
Liposome
|
Others
|
DSPE-PEG-Amine, MW 5000 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. DSPE-PEG-Amine, MW 5000 (ammonium) amino group can be converted to aromatic aldehydes that react with acetone-protected aromatic hydrazides on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes produce liposome-Bah-BCA conjugates by forming diaryl hydrazone (BAH) with target enzyme molecules. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.
|
-
- HY-156096
-
|
HDAC
Histone Methyltransferase
Caspase
Apoptosis
DNA/RNA Synthesis
|
Cancer
|
HDAC3-IN-2 (compound 4i) is a pyrazinyl hydrazide-based HDAC3 inhibitor (IC50: 14 nM) that efficiently targets triple-negative breast cancer cells. HDAC3-IN-2 is cytotoxic with an IC50 of 0.55 μM against 4T1 and an IC50 of 0.74 μM against MDA-MB-231. HDAC3-IN-2 has anti-tumor efficacy in vivo in tumor-bearing mouse models, selectively increasing the acetylation levels of H3K9, H3K27 and H4K12, increasing the contents of apoptosis-related caspase-3, caspase-7 and cytochrome c, and reducing Proliferation-related Bcl-2, CD44, EGFR, and Ki-67 levels .
|
-
Cat. No. |
Product Name |
Type |
-
- HY-D1564
-
-
- HY-D1880
-
|
Fluorescent Dyes/Probes
|
Sulfo-Cy5 hydrazide is a fluorescent dye containing a hydrazide functionality (Ex/Em=646/662 nm) .
|
-
- HY-D1882
-
|
Fluorescent Dyes/Probes
|
Cy5.5 hydrazide is a fluorescent dye containing a hydrazide functionality. Cy5.5 hydrazide can be used to label aldehydes and ketones .
|
-
- HY-D1324
-
|
Fluorescent Dyes/Probes
|
Cyanine5.5 hydrazide, an analog of Cyanine5.5 fluorophore, is a near-infrared (NIR) fluorescent dye. Cyanine5.5 hydrazide is used for labeling of biomolecules through the condensation between the hydrazide groups and the carbonyl groups. (λex=684 nm, λem=710 nm) .
|
-
- HY-137100
-
Cyanine5 hydrazide
|
Fluorescent Dyes/Probes
|
Cy 5 hydrazide (Cyanine5 hydrazide) is a fluorescent dye for aldehydes and ketones. Cy 5 hydrazide can be used for labeling proteins .
|
-
- HY-151644
-
|
Fluorescent Dyes/Probes
|
Fluorescein hydrazide is a colorimetric probe formed by the reaction of dihydrazine adipate with fluorescein isothiocyanate. Fluorescein hydrazide can be used to label aldehyde and ketone groups .
|
-
- HY-151774
-
|
Fluorescent Dyes/Probes
|
TAMRA hydrazide (6-isomer) is a click chemistry reagent that can be coupled to carbonyl compounds. The dye hydrazide in TAMRA hydrazide (6-isomer) labels carbonyl compounds such as aldehydes and ketones. TAMRA in TAMRA hydrazide (6-isomer) is a xanthene red fluorophore that reacts with terminal alkynes .
|
-
- HY-D1586
-
|
Fluorescent Dyes/Probes
|
Cyanine5 Boc-hydrazide (chloride) is a cyanine5-labeled and Boc-protected hydrazide fluorescent dye.
|
-
- HY-D1667
-
|
Fluorescent Dyes/Probes
|
BDP 558/568 hydrazide is a carbonyl reactive hydrazide derivative of BDP 558/568 (BDP 558/568: Ex=558 nm, Em=568 nm). BDP 558/568 hydrazide can be used for the labeling of aldehydes or ketones.
|
-
- HY-151690
-
|
Fluorescent Dyes/Probes
|
FAM hydrazide, 6-isomer is a hydrazide derivative of fluorescein (FAM). FAM is a xanthene dye, a parent of fluorescein dye series. FAM hydrazide, 6-isomer can be used for the labeling of carbonyl compounds, aldehydes, and ketones .
|
-
- HY-132264
-
|
Fluorescent Dyes/Probes
|
FAM hydrazide, 6-isomer hydrochloride is a hydrazide derivative of fluorescein (FAM). FAM is a xanthene dye, a parent of fluorescein dye series. FAM hydrazide, 6-isomer hydrochloride can be used for the labeling of carbonyl compounds, aldehydes, and ketones .
|
-
- HY-D2251
-
-
- HY-123645
-
|
Fluorescent Dyes/Probes
|
Rhodamine B hydrazide is a good probe for sulfite, with colorless and non-fluorescent properties. While the emission is related to the concentration of sulfite (5-800 ng/mL; detection limit=1.4 ng/mL (3σ)). Sulfite reduces dissolved oxygen to yield superoxide radicals, which binds to Rhodamine B hydrazide to form Rhodamine B. Rhodamine B hydrazide gives Rhodamine B-like fluorescence in the presence of sulfite, which is enhanced by Tween 80 surfactant micelles. Rhodamine B hydrazide has an absorption maximum at 554 nm and a fluorescence emission maximum at 574 nm .
|
-
- HY-114351
-
|
Fluorescent Dyes/Probes
|
BODIPY FL Hydrazide is a green-fluorescent dye, BODIPY FL Hydrazide is reactive with aldehyde/ketone on polysaccharides and glycoproteins, yielding a reversible Schiff base product that can be transformed to a stable linkage using a reducing agent like sodium borohydride or sodium cyanoborohydride. (λex=495 nm, λem=516 nm) .
|
-
- HY-D1619
-
|
Fluorescent Dyes/Probes
|
Cyanine3 hydrazide dichloride is a carbonyl reactive dye. Cyanine3 hydrazide dichloride allows the labelling of various carbonyl-containing molecules such as antibodies and other glycoproteins after oxidation by periodate, proteins or reducing sugars after oxidative stress or deamination .
|
-
- HY-D1599
-
R6GH
|
Fluorescent Dyes/Probes
|
Rhodamine 6G hydrazide (R6GH) is a fluorescent dye. Rhodamine 6G hydrazide can be used in selective colorimetric and fluorescent sensing .
|
-
- HY-D1861
-
|
Fluorescent Dyes/Probes
|
Sulfo-Cy3 hydrazide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative with hydrazine functionality. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The hydrazide group of Sulfo-Cy3 hydrazide can form hydrazinone coupling with molecules containing aldehydes or ketones to form covalent bonds. Therefore, Cy3 azide plus can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-D2151
-
|
Fluorescent Dyes/Probes
|
AF 430 hydrazide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 430 nm and an emission wavelength of 542 nm. AF 430 hydrazide can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) via the Azide group and molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups. To achieve specific coupling of dye labels and biomolecules.
|
-
- HY-D1601
-
|
Fluorescent Dyes/Probes
|
N-Aminofluorescein is a fluorescein hydrazide with spiro form, a highly selective and sensitive fluorescence probe for Cu 2+. N-Aminofluorescein has no selective fluorescence response to other common metal ions, can be used for direct detection of Cu 2+ in biological systems with λex/em=495/516 nm .
|
-
- HY-D2013
-
|
Fluorescent Dyes/Probes
|
ATTO 488 hydrazid is a hydrazide derivative of ATTO 488 with excitation/emission maxima at 500/520 nm.
|
-
- HY-D2053
-
|
Fluorescent Dyes/Probes
|
ATTO 532 hydrazid is a hydrazide derivative of ATTO 532 with maximum excitation/emission wavelengths: 532/552 nm.
|
-
- HY-D2011
-
|
Fluorescent Dyes/Probes
|
ATTO 565 hydrazid is a hydrazide derivative of ATTO 565 with maximum excitation/emission wavelengths: 564/590 nm.
|
-
- HY-D2037
-
|
Fluorescent Dyes/Probes
|
ATTO 550 hydrazid is a hydrazide derivative of ATTO 550 with maximum excitation/emission wavelengths: 554/576 nm.
|
-
- HY-D2034
-
|
Fluorescent Dyes/Probes
|
ATTO 514 hydrazid is a hydrazide derivative of ATTO 514 with maximum excitation/emission wavelengths: 511/531 nm.
|
Cat. No. |
Product Name |
Type |
-
- HY-101885
-
Biotinamidocaproyl hydrazide; BACH; (+)-Biotinamidohexanoic Acid hydrazide; Biotin Aminocaproyl hydrazide
|
Biochemical Assay Reagents
|
Biotin LC hydrazide is a long chain protein modification reagent, which can transform periodate-oxidized glycoproteins.
|
-
- HY-100215
-
-
- HY-125501
-
Biotin-(AC5)2-hydrazide
|
Biochemical Assay Reagents
|
Biotin-XX hydrazide (Biotin-(AC5)2-hydrazide) is a carbonyl-reactive biotinylation reagent which contains two aminohexanoic acid spacers. Biotin-XX hydrazide has higher efficiency of avidin-binding .
|
-
- HY-156145
-
-
- HY-155907
-
DSPE-PEG-NH2, MW 5000 ammonium
|
Drug Delivery
|
DSPE-PEG-Amine, MW 5000 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. DSPE-PEG-Amine, MW 5000 (ammonium) amino group can be converted to aromatic aldehydes that react with acetone-protected aromatic hydrazides on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes produce liposome-Bah-BCA conjugates by forming diaryl hydrazone (BAH) with target enzyme molecules. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.
|
Cat. No. |
Product Name |
Target |
Research Area |
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-B0329S
-
|
Isoniazid-d4 is the deuterium labeled Isoniazid. Isoniazid (INH) is a proagent and must be activated by a bacterial catalase-peroxidase enzyme KatG. Isoniazid is bactericidal to rapidly dividing mycobacteria and has anti-tuberculostatic activity[1][2][3][4].
|
-
-
- HY-B1703S
-
|
Nifursol- 13C6 is the 13C6 labeled Nifursol. Nifursol is a potent and orally active veterinary antibiotic for the prevention of histomoniasis. Nifursol rapidly metabolizes to form the metabolic marker 3,5-dinitrosalicyclic acid hydrazide (DNSAH) which can persist for a long time. Nifursol is widely used for the research of Escherichia Gastroenteropathy in poultry, fowl and aquatic animal.
|
-
-
- HY-59354S
-
|
Maleic hydrazide-d2 is the deuterium labeled Maleic hydrazide[1]. Maleic hydrazide is extensively used as a systemic plant growth regulator and as a herbicide. Maleic hydrazide acts as an inhibitor of the synthesis of nucleic acids and proteins[2][3].
|
-
-
- HY-W111879S
-
|
Oxamic acid hydrazide- 15N3 is the 15N3 labeled Oxamic acid hydrazide.
|
-
Cat. No. |
Product Name |
|
Classification |
-
- HY-140814
-
|
|
Azide
PROTAC Synthesis
|
Azido-PEG4-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-133438
-
|
|
PROTAC Synthesis
BCN
|
BCN-PEG4-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . BCN-PEG4-hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-133427
-
|
|
Alkynes
ADC Synthesis
|
Propargyl-PEG4-hydrazide is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG4-hydrazide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140815
-
|
|
PROTAC Synthesis
Azide
|
Azido-PEG8-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-130886
-
|
|
Azide
PROTAC Synthesis
|
N3-PEG12-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N3-PEG12-Hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-133320
-
|
|
Azide
PROTAC Synthesis
|
N3-PEG16-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N3-PEG16-Hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-133321
-
|
|
PROTAC Synthesis
Azide
|
N3-PEG24-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N3-PEG24-Hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140816
-
|
|
PROTAC Synthesis
Azide
|
Azido-PEG2-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG2-hydrazide-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140817
-
|
|
PROTAC Synthesis
Azide
|
Azido-PEG4-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-hydrazide-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
Your information is safe with us. * Required Fields.
Inquiry Information
- Product Name:
- Cat. No.:
- Quantity:
- MCE Japan Authorized Agent: