2. Cell Cycle/DNA Damage
  3. DNA/RNA Synthesis
  4. Maleic hydrazide

Maleic hydrazide 

Cat. No.: HY-59354 Purity: 99.91%
COA Handling Instructions

Maleic hydrazide is extensively used as a systemic plant growth regulator and as a herbicide. Maleic hydrazide acts as an inhibitor of the synthesis of nucleic acids and proteins.

For research use only. We do not sell to patients.

Maleic hydrazide Chemical Structure

Maleic hydrazide Chemical Structure

CAS No. : 123-33-1

Size Price Stock Quantity
Free Sample (0.1 - 0.5 mg)   Apply Now  
Solution
10 mM * 1 mL in DMSO USD 61 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
 USD 61 In-stock
Estimated Time of Arrival: December 31
Solid
500 mg USD 55 In-stock
Estimated Time of Arrival: December 31
1 g   Get quote  
5 g   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Maleic hydrazide is extensively used as a systemic plant growth regulator and as a herbicide. Maleic hydrazide acts as an inhibitor of the synthesis of nucleic acids and proteins[1][2].

In Vitro

Maleic hydrazide is used in agriculture-in despite its known effect as a mutagenic and clastogenic agent. Maleic hydrazide had lower IC50 values for all cell lines compared to Ethephon. Maleic hydrazide also showed least cytotoxicity on Vero cells, followed by Hep2 and HepG2 cells[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo

Maleic hydrazide has a low acute toxicity by oral, dermal, and inhalation routes of exposure[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

112.09

Appearance

Solid

Formula

C4H4N2O2
CAS No.
SMILES

O=C1C=CC(NN1)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (1115.18 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.9214 mL 44.6070 mL 89.2140 mL
5 mM 1.7843 mL 8.9214 mL 17.8428 mL
10 mM 0.8921 mL 4.4607 mL 8.9214 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (18.56 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (18.56 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (18.56 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation

Purity: 99.91%

COA (250 KB) HNMR (215 KB) LCMS (113 KB)

Handling Instructions (2659 KB)
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Maleic hydrazide123-33-1DNA/RNA SynthesisherbicidegrowthplantvegetablescytotoxicInhibitorinhibitorinhibit

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