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Results for "

methanesulfonate

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acyltransferase (1) Adrenergic Receptor (1) Antibiotic (1) Apoptosis (1) Bacterial (1) Biochemical Assay Reagents (2) CDK (1) Complement System (1) CRFR (1) DNA/RNA Synthesis (1) Dopamine Receptor (5) Fluorescent Dye (1) Histamine Receptor (2) Isotope-Labeled Compounds (5) mAChR (3) Monoamine Oxidase (1) P-glycoprotein (1) PI3K (1) PKC (1) Sodium Channel (1) Thrombin (1) TRP Channel (1) α-synuclein (1)
By Research Areas:	Cancer (10) Cardiovascular Disease (4) Endocrinology (1) Infection (2) Inflammation/Immunology (2) Metabolic Disease (2) Neurological Disease (11)

By Targets:

Acyltransferase (1)

Adrenergic Receptor (1)

Antibiotic (1)

Apoptosis (1)

Bacterial (1)

Biochemical Assay Reagents (2)

CDK (1)

Complement System (1)

CRFR (1)

DNA/RNA Synthesis (1)

Dopamine Receptor (5)

Fluorescent Dye (1)

Histamine Receptor (2)

Isotope-Labeled Compounds (5)

mAChR (3)

Monoamine Oxidase (1)

P-glycoprotein (1)

PI3K (1)

PKC (1)

Sodium Channel (1)

Thrombin (1)

TRP Channel (1)

α-synuclein (1)

By Research Areas:

Cancer (10)

Cardiovascular Disease (4)

Endocrinology (1)

Infection (2)

Inflammation/Immunology (2)

Metabolic Disease (2)

Neurological Disease (11)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-10550A

*Tariquidar methanesulfonate, hydrate* 45+ Cited Publications XR9576 methanesulfonate, hydrate	P-glycoprotein	Cancer
Tariquidar methanesulfonate, hydrate (XR9576 methanesulfonate, hydrate) is a potent and specific inhibitor of P-glycoprotein (P-gp) with a K_d of 5.1 nM.

HY-W015854S

Ethyl methanesulfonate-d5

Isotope-Labeled Compounds Others

Ethyl methanesulfonate-d₅ is the deuterium labeled Ethyl methanesulfonate[1].

*Ethyl methanesulfonate-d5*	Isotope-Labeled Compounds	Others
Ethyl methanesulfonate-d₅ is the deuterium labeled Ethyl methanesulfonate[1].

HY-16297

Abemaciclib methanesulfonate Maximum Cited Publications 74 Publications Verification LY2835219 methanesulfonate	CDK	Cancer
Abemaciclib methanesulfonate (LY2835219 methanesulfonate) is a selective CDK4/6 inhibitor with IC₅₀s of 2 nM and 10 nM for CDK4 and CDK6, respectively .

HY-108464A

Phenamil methanesulfonate	Sodium Channel TRP Channel	Metabolic Disease Inflammation/Immunology
Phenamil methanesulfonate, an analog of Amiloride (HY-B0285), is a more potent and less reversible epithelial sodium channel (ENaC) blocker with an IC₅₀ of 400 nM . Phenamil methanesulfonate is also a competive inhibitor of TRPP3 and inhibits TRPP3-mediated Ca ²⁺ transport with an IC₅₀ of 140 nM in a Ca ²⁺ uptake assay . Phenamil methanesulfonate is an intriguing small molecule to promote bone repair by strongly activating BMP signaling pathway . Phenamil methanesulfonate is used for the research of cystic fibrosis lung disease .

HY-W034344S

Sodium methanesulfonate-d3

Isotope-Labeled Compounds Others

Sodium methanesulfonate-d₃ is the deuterium labeled Sodium methanesulfonate[1].
HY-W004702S

Methyl methanesulfonate-d3

METHYLMETHANE SULPHONATE-d₃
Isotope-Labeled Compounds Others

Methyl methanesulfonate-d₃ is the deuterium labeled Methyl methanesulfonate[1].

*Sodium methanesulfonate-d3*	Isotope-Labeled Compounds	Others
Sodium methanesulfonate-d₃ is the deuterium labeled Sodium methanesulfonate[1].

*Methyl methanesulfonate-d3* METHYLMETHANE SULPHONATE-d₃	Isotope-Labeled Compounds	Others
Methyl methanesulfonate-d₃ is the deuterium labeled Methyl methanesulfonate[1].

HY-103378

NBI 35965 methanesulfonate	CRFR	Neurological Disease
NBI 35965 methanesulfonate is a selective, orally active and brain-penetrant corticotropin-releasing factor receptor 1 (CRF1) antagonist with a K_i value of 4 nM and a pK_i value of 8.5. NBI 35965 methanesulfonate does not inhibit CRF2. NBI 35965 methanesulfonate reduces CRF or stress-induced adrenocorticotropic hormone (ACTH) production in vivo with pIC₅₀ values of 7.1 and 6.9, respectively. NBI 35965 methanesulfonate shows anxiolytic effects .

HY-W004702

Methyl methanesulfonate	Biochemical Assay Reagents	Others
Methyl methanesulfonate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W015854

Ethyl methanesulfonate	Biochemical Assay Reagents	Others
Ethyl methanesulfonate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-108341A

PF-06424439 methanesulfonate 5+ Cited Publications	Acyltransferase	Metabolic Disease
PF-06424439 methanesulfonate is an oral, potent and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC₅₀ of 14 nM . PF-06424439 methanesulfonate is slowly reversible, time-dependent inhibitor, which inhibits DGAT2 in a noncompetitive mode with respect to the acyl-CoA substrate .

HY-A0214

*Colistin methanesulfonate* sodium salt** 1 Publications Verification
Colistin methanesulfonate sodium salt exhibits MIC values ranged from 4 to 16 mg/liter against susceptible strains (P. aeruginosa) .

HY-123938A

CYH33 methanesulfonate	PI3K	Cancer
CYH33 methanesulfonate is an orally active, highly selective PI3Kα inhibitor with IC₅₀s of 5.9 nM/598 nM/78.7 nM/225 nM against α/β/δ/γ isoform, respectively. CYH33 methanesulfonate inhibits phosphorylation of Akt, ERK and induces significant G1 phase arrest in breast cancer cells and non-small cell lung cancer (NSCLC) cells. CYH33 methanesulfonate has potent activity against solid tumors .

HY-W011777S

Tricaine-d5 methanesulfonate MS-222-d₅	Isotope-Labeled Compounds	Neurological Disease
Tricaine-d₅ (methanesulfonate) is the deuterium labeled Tricaine-d5 methanesulfonate. Tricaine methanesulfonate (MS-222) is a commonly used anaesthetic agent for immobilization of aquatic species. Tricaine methanesulfonate, the most widely used anaesthetic in fish, has been shown to induce embryotoxic effects in zebrafish[1][2].

HY-14205

NW-1772 methanesulfonate	Monoamine Oxidase	Neurological Disease
NW-1772 (methanesulfonate) (22b) is a potent and selective monoamine oxidase (MAO) B inhibitor. NW-1772 (methanesulfonate) is the equivalent of HY-111156 NW-1772. NW-1772 has some advantages, such as rapid blood-brain barrier penetration, short-acting and reversible inhibitory activity, slight inhibition of selected cytochrome P450s, and low in vitro toxicity. NW-1772 can be used for the research of neurodegenerative diseases .

HY-W011777

Tricaine methanesulfonate 4 Publications Verification MS-222	Others	Neurological Disease
Tricaine methanesulfonate (MS-222) is common used to immobilize fish for marking or transport and to suppress sensory systems during invasive procedures .

HY-124223

AF-DX 384 methanesulfonate	mAChR	Neurological Disease
AF-DX 384 (methanesulfonate) is a selective antagonist of M2 and M4 muscarinic acetylcholine receptors (K_is=6.03 and 10 nM, respectively) . AF-DX 384 (methanesulfonate) reverses deficits in novel object recognition and passive avoidance in aged rats, as well as in young rats with impairments induced by scopolamine .

HY-13720A

Pergolide mesylate 1 Publications Verification Pergolide methanesulfonate; LY127809	Dopamine Receptor	Neurological Disease
Pergolide mesylate (Pergolide methanesulfonate), an Ergoline derivative, is a potent and orally active dopamine D₁ and D₂ receptors agonist. Pergolide mesylate can be used for Parkinson's disease and hyperprolactinaemia research .

HY-B0362A

Phentolamine mesylate 3 Publications Verification Phentolamine methanesulfonate	Adrenergic Receptor	Cardiovascular Disease Endocrinology Cancer
Phentolamine mesylate (Phentolamine methanesulfonate) is a reversible, non-selective, and orally active blocker of α1 and α2 adrenergic receptor that expands blood vessels to reduce peripheral vascular resistance. Phentolamine mesylate can be used for the research of pheochromocytoma-related hypertension, heart failure and erectile dysfunction .

HY-120220

Piposulfan A-20968; Ancyte	Others	Cancer
Piposulfan (Ancyte) is a methanesulfonate, alkylating derivative of piperazine. Piposulfan has potential antineoplastic activity. Piposulfan can be used for the research of cancer .

HY-50875

BCX 1470 methanesulfonate	Complement System	Inflammation/Immunology
BCX 1470 methanesulfonate inhibits the esterolytic activity of factor D (IC₅₀=96 nM) and C1s (IC₅₀=1.6 nM), 3.4- and 200-fold better, respectively, than that of trypsin.

HY-119993

AR03 BMH-23	DNA/RNA Synthesis	Cancer
AR03 (BMH-23) is an apurinic/apyrimidinic endonuclease 1 (Ape1) inhibitor with an IC₅₀ of 2.1 µM. AR03 has low affinity for double-stranded DNA. AR03 potentiates the cytotoxicity of methyl methanesulfonate and temozolomide in SF767 cells .

HY-13720AS

Pergolide-d7 mesylate Pergolide methanesulfonate-d₇; LY127809-d₇	Isotope-Labeled Compounds Dopamine Receptor	Neurological Disease
Pergolide-d₇ (mesylate) is the deuterium labeled Pergolide mesylate. Pergolide mesylate (Pergolide methanesulfonate), an Ergoline derivative, is a potent and orally active dopamine D1 and D2 receptors agonist. Pergolide mesylate can be used for Parkinson's disease and hyperprolactinaemia research[1][2].

HY-120475A

PBT434 mesylate ATH434 mesylate	α-synuclein	Neurological Disease
PBT434 methanesulfonate is a potent, orally active and cross the blood-brain barrier α-synuclein aggregation inhibitor. PBT434 methanesulfonate can be used as a iron chelator and modulates transcellular iron trafficking. PBT434 methanesulfonate inhibits iron-mediated redox activity and iron-mediated aggregation of α-synuclein. PBT434 methanesulfonate prevents the loss of substantia nigra pars compacta neurons (SNpc). PBT434 methanesulfonate has the potential for the research of Parkinson’s disease (PD) .

HY-108166A

Hydroxystilbamidine bis(fluoroGlod)	Fluorescent Dye	Infection
Hydroxystilbamidine bis(methanesulfonate), a dye capable of binding to both DNA and RNA, has been found to be a powerful inhibitor of cellular ribonucleases.

HY-B0520A

Benztropine mesylate 4 Publications Verification Benzatropine mesylate; Benzotropine mesylate; Benztropine methanesulfonate	Dopamine Receptor mAChR Histamine Receptor	Neurological Disease Cancer
Benztropine mesylate (Benzatropine mesylate) is an orally active centrally acting anticholinergic agent that can be used for Parkinson's disease research. Benztropine mesylate is an anti-histamine agent and a dopamine re-uptake inhibitor. Benztropine mesylate is also a human D₂ dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects .

HY-B0735A

Fenoldopam mesylate 4 Publications Verification Fenoldopam methanesulfonate; SKF-82526 mesylate	Dopamine Receptor Apoptosis	Cardiovascular Disease Cancer
Fenoldopam mesylate (SKF-82526) is a D₁ receptor agonist and a novel lysine-specific demethylase 1 (LSD1) inhibitor (IC₅₀=0.8974 μM). Fenoldopam mesylate shows anti-hypertensive effects, anti-cancer cell proliferation activity and can induce cells apoptosis .

HY-B0724A

Pazufloxacin mesylate

T-3762; Pazufloxacin methanesulfonate; Pazufloxacin mesilate
Bacterial Antibiotic Infection

Pazufloxacin (T-3761) mesylate is a fluoroquinolone antibiotic.

Pazufloxacin mesylate T-3762; Pazufloxacin methanesulfonate; Pazufloxacin mesilate	Bacterial Antibiotic	Infection
Pazufloxacin (T-3761) mesylate is a fluoroquinolone antibiotic.

HY-10274A

Dabigatran etexilate mesylate 3 Publications Verification BIBR 1048MS; Dabigatran etexilate methanesulfonate	Thrombin	Cardiovascular Disease
Dabigatran etexilate mesylate (BIBR 1048MS) is an orally active proagent of Dabigatran (a direct inhibitor of thrombin). Dabigatran etexilate mesylate has anticoagulant effects and is used for the prophylaxis of venousthromboembolism and stroke due to atrial fibrillation .

HY-13866

Ro 31-8220 mesylate 10+ Cited Publications Ro 31-8220 methanesulfonate; Bisindolylmaleimide IX mesylate	PKC	Cardiovascular Disease Neurological Disease Cancer
Ro 31-8220 mesylate is a potent PKC inhibitor, with IC₅₀s of 5, 24, 14, 27, 24 and 23 nM for PKCα, PKCβI, PKCβII, PKCγ, PKCε and rat brain PKC, respectively. Ro 31-8220 also significantly inhibits MAPKAP-K1b, MSK1, S6K1 and GSK3β (IC₅₀s, 3, 8, 15, and 38 nM, respectively), with no effect on MKK3, MKK4, MKK6 and MKK7.

HY-B0520AR

Benztropine mesylate (Standard) Benzatropine mesylate (Standard); Benzotropine mesylate (Standard); Benztropine methanesulfonate (Standard)	Dopamine Receptor mAChR Histamine Receptor	Neurological Disease Cancer
Benztropine (mesylate) (Standard) is the analytical standard of Benztropine (mesylate). This product is intended for research and analytical applications. Benztropine mesylate (Benzatropine mesylate) is an orally active centrally acting anticholinergic agent that can be used for Parkinson's disease research. Benztropine mesylate is an anti-histamine agent and a dopamine re-uptake inhibitor. Benztropine mesylate is also a human D₂ dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects .

Hydroxystilbamidine bis(fluoroGlod)	DNA Stain
Hydroxystilbamidine bis(methanesulfonate), a dye capable of binding to both DNA and RNA, has been found to be a powerful inhibitor of cellular ribonucleases.

Methyl methanesulfonate	Biochemical Assay Reagents
Methyl methanesulfonate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Ethyl methanesulfonate	Biochemical Assay Reagents
Ethyl methanesulfonate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

*Ethyl methanesulfonate-d5*
Ethyl methanesulfonate-d₅ is the deuterium labeled Ethyl methanesulfonate[1].

*Sodium methanesulfonate-d3*
Sodium methanesulfonate-d₃ is the deuterium labeled Sodium methanesulfonate[1].

*Methyl methanesulfonate-d3*
Methyl methanesulfonate-d₃ is the deuterium labeled Methyl methanesulfonate[1].

Tricaine-d5 methanesulfonate
Tricaine-d₅ (methanesulfonate) is the deuterium labeled Tricaine-d5 methanesulfonate. Tricaine methanesulfonate (MS-222) is a commonly used anaesthetic agent for immobilization of aquatic species. Tricaine methanesulfonate, the most widely used anaesthetic in fish, has been shown to induce embryotoxic effects in zebrafish[1][2].

Pergolide-d7 mesylate
Pergolide-d₇ (mesylate) is the deuterium labeled Pergolide mesylate. Pergolide mesylate (Pergolide methanesulfonate), an Ergoline derivative, is a potent and orally active dopamine D1 and D2 receptors agonist. Pergolide mesylate can be used for Parkinson's disease and hyperprolactinaemia research[1][2].

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