Methyl methanesulfonate-d3
Methyl methanesulfonate-d3 is the deuterium labeled Methyl methanesulfonate (HY-W004702). Methyl methanesulfonate is an alkylating agent which transfers methyl groups, and induces DNA damage. Methyl methanesulfonate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
For research use only. We do not sell to patients.
- CAS No.: 91419-94-2
- Formula: C2H3D3O3S
- Molecular Weight:113.15
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Storage:
RT, protect from light.
In solvent -80°C, 1 year , -20°C, 6 months
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 91419-94-2
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Unlabeled Cas 66-27-3
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Appearance Liquid
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Molecular Weight 113.15
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Formula C2H3D3O3S
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Color Colorless to light yellow
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SMILES
[2H]C([2H])(OS(C)(=O)=O)[2H]
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Synonyms
METHYLMETHANE SULPHONATE-d3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
RT, protect from light
In solvent -80°C 1 year -20°C 6 months
Purity & Documentation
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Data Sheet (273 KB)
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SDS (731 KB)
- English - EN (731 KB)
- Français - FR (731 KB)
- Deutsch - DE (731 KB)
- Norwegian - NO (731 KB)
- Español - ES (731 KB)
- Swedish - SV (731 KB)
- Italian - IT (731 KB)
- Korean - KR (731 KB)
- Portuguese - PT (731 KB)
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Handling Instructions (2659 KB)
References
[1]. Jiang Y, et al., Methyl methanesulfonate induces necroptosis in human lung adenoma A549 cells through the PIG-3-reactive oxygen species pathway. Tumour Biol. 2016 Mar;37(3):3785-95. [Content Brief]
[2]. Hosseinzadeh H, et al., Protective effect of Crocus sativus stigma extract and crocin (trans-crocin 4) on methyl methanesulfonate-induced DNA damage in mice organs. DNA Cell Biol. 2008 Dec;27(12):657-64. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)