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tropi

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By Targets:	5-HT Receptor (4) AP-1 (2) Autophagy (3) Biochemical Assay Reagents (1) Dopamine Transporter (1) Drug Derivative (2) Drug Intermediate (6) Endogenous Metabolite (3) Environmental Pollutants (1) FXR (2) Isotope-Labeled Compounds (2) JAK (2) mAChR (12) nAChR (4) NF-κB (2) Nuclear Factor of activated T Cells (NFAT) (2) p38 MAPK (2) Reference Standards (10)
By Research Areas:	Cancer (10) Cardiovascular Disease (9) Inflammation/Immunology (3) Neurological Disease (19)

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Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1205

Atropine 20+ Cited Publications tropine tropate; DL-Hyoscyamine	Environmental Pollutants Endogenous Metabolite mAChR	Cardiovascular Disease Neurological Disease Cancer
Atropine (Tropine tropate) is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC₅₀ values of 0.39 and 0.71 nM for Human mAChR M₄ and Chicken mAChR M₄, respectively. Atropine inhibits ACh-induced relaxations in human pulmonary veins. Atropine can be used for research of anti-myopia and bradycardia .

HY-107418

Tropifexor 5+ Cited Publications LJN452	FXR Autophagy	Cardiovascular Disease
Tropifexor (LJN452) is a highly potent agonist of FXR with an EC₅₀ of 0.2 nM .

HY-B0394

Atropine sulfate monohydrate Maximum Cited Publications 25 Publications Verification tropine tropate sulfate monohydrate; DL-Hyoscyamine sulfate monohydrate	mAChR	Cardiovascular Disease Neurological Disease Cancer
Atropine (Tropine tropate) sulfate monohydrate is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC₅₀ values of 0.39 and 0.71 nM for Human mAChR M₄ and Chicken mAChR M₄, respectively. Atropine sulfate monohydrate inhibits ACh-induced relaxations in human pulmonary veins. Atropine sulfate monohydrate can be used for research of anti-myopia and bradycardia .

HY-B1205A

Atropine sulfate Maximum Cited Publications 25 Publications Verification tropine tropate sulfate; DL-Hyoscyamine sulfate; Sulfatropinol	mAChR	Cardiovascular Disease Neurological Disease Cancer
Atropine (Tropine tropate) sulfate is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC₅₀ values of 0.39 and 0.71 nM for Human mAChR M₄ and Chicken mAChR M₄, respectively. Atropine sulfate inhibits ACh-induced relaxations in human pulmonary veins. Atropine sulfate can be used for research of anti-myopia and bradycardia .

HY-B0321

Tropicamide 5 Publications Verification Ro 1-7683	mAChR	Neurological Disease
Tropicamide (Ro 1-7683) is a selective M4 muscarinic acetylcholine receptor antagonist. When used as an eye drop, Tropicamide causes short-term mydriasis (pupil dilation) and cycloplegia. Tropicamide can be used in the research of neurological diseases, such as epilepsy .

HY-B0020

Tropisetron Hydrochloride 4 Publications Verification SDZ-ICS-930	5-HT Receptor nAChR	Neurological Disease Inflammation/Immunology Cancer
Tropisetron Hydrochloride (SDZ-ICS-930) is an effective neuroprotective agent that acts as a 5-HT3 receptor antagonist, a calmodulin inhibitor, and an α7-nAChRreceptor agonist, with an IC₅₀ of 70.1 nM for the 5-HT3 receptor. Tropisetron Hydrochloride has anti-inflammatory properties and immune-regulating functions, effectively alleviating symptoms associated with chemotherapy and post-surgery. Tropisetron Hydrochloride reduces Ab (HY-P4867)-induced hippocampal neuroinflammation .

HY-W041194

Tropic acid DL-tropic acid	Drug Intermediate	Others
Tropic acid (DL-Tropic acid) is an active small molecule that can be used as the pharmaceutical intermediate .

HY-Y0135

Tropinone	Drug Intermediate	Cancer
Tropinone is an organic synthesis intermediate and a skeleton for constructing derivatives containing thiazole rings and other structures. Tropinone derivatives have anticancer activities such as inducing tumor cell apoptosis and inhibiting tyrosinase activity, and can be used in research such as anticancer drug development and tyrosinase inhibitor design .

HY-B0072

Tropisetron 4 Publications Verification SDZ-ICS-930 free base	5-HT Receptor nAChR p38 MAPK NF-κB AP-1 Nuclear Factor of activated T Cells (NFAT) JAK	Neurological Disease Inflammation/Immunology Cancer
Tropisetron is an orally active 5-HT3R antagonist (K_i = 5.3 nM) as well as being a potent and selective α7 nicotinic partial agonist (EC₅₀ = 1.3 μM). Tropisetron prevents phosphorylation and activation of the p38 MAPK. Tropisetron inhibits both IL-2 gene transcription and IL-2 synthesis in stimulated T cells. Tropisetron inhibits the binding to DNA and the transcriptional activity of NFAT and AP-1. Tropisetron is anti-inflammatory and antiemetic. Tropisetron has antitumor and neuroprotective effects. Tropisetron can be studied in research for diseases including hemorrhagic cystitis, chronic joint inflammation, lung cancer and chronic cerebral hypoperfusion .

HY-N7061

Tropine	Drug Intermediate	Neurological Disease
Tropine is a tropane alkaloid. Tropine serves as an important intermediate for the synthesis of anticholinergics and bronchodilators such as Atropine (HY-B1205) and Scopolamine (HY-N0296) .

HY-B0394S

Atropine-d5 tropine tropate-d₅; DL-Hyoscyamine-d₅	mAChR Autophagy	Neurological Disease
Atropine-d₅ is the deuterium labeled Atropine (sulfate monohydrate). Atropine (Tropine tropate) sulfate monohydrate is a broad-spectrum and competitive muscarinic acetylcholine receptor (mAChR) antagonist with anti-myopia effect .

HY-B1205R

Atropine (Standard) tropine tropate (Standard); DL-Hyoscyamine (Standard)	Reference Standards mAChR Endogenous Metabolite	Cardiovascular Disease Neurological Disease
Atropine (Standard) is the analytical standard of Atropine. This product is intended for research and analytical applications. Atropine (Tropine tropate) is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC₅₀ values of 0.39 and 0.71 nM for Human mAChR M₄ and Chicken mAChR M₄, respectively. Atropine inhibits ACh-induced relaxations in human pulmonary veins. Atropine can be used for research of anti-myopia and bradycardia .

HY-B0321S

Tropicamide-d3 Ro 1-7683-d₃	mAChR	Neurological Disease
Tropicamide-d₃ is the deuterium labeled Tropicamide . Tropicamide (Ro 1-7683) is a selective M4 muscarinic acetylcholine receptor antagonist. Tropicamide produces short acting mydriasis (dilation of the pupil) and cycloplegia when applied as eye drops .

HY-B1205S

(Rac)-Atropine-d3 1 Publications Verification (Rac)-tropine tropate-d₃; (Rac)-Hyoscyamine-d₃	mAChR Endogenous Metabolite Isotope-Labeled Compounds	Others
(Rac)-Atropine-d₃ is the deuterium labeled (Rac)-Atropine[1].

HY-B1205AR

Atropine sulfate (Standard) tropine tropate sulfate (Standard); DL-Hyoscyamine sulfate (Standard); Sulfatropinol (Standard)	Reference Standards mAChR	Cardiovascular Disease Neurological Disease
Atropine (sulfate) (Standard) is the analytical standard of Atropine (sulfate). This product is intended for research and analytical applications. Atropine (Tropine tropate) sulfate is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC50 values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine sulfate inhibits ACh-induced relaxations in human pulmonary veins. Atropine sulfate can be used for research of anti-myopia and bradycardia .

HY-W033010

Pseudotropine β-tropine	Drug Derivative	Others
Pseudotropine (β-Tropine), a derivative of Tropane, is a plant alkaloid .

HY-B0072S

Tropisetron-d5 SDZ-ICS-930-d5 free base	Isotope-Labeled Compounds nAChR p38 MAPK 5-HT Receptor AP-1 NF-κB Nuclear Factor of activated T Cells (NFAT) JAK	Neurological Disease Inflammation/Immunology Cancer
Tropisetron-d₅ (SDZ-ICS-930-d₅ (free base)) is deuterium labeled Tropisetron. Tropisetron (SDZ-ICS-930 free base) is an orally active anti-inflammatory and antiemetic agent. Tropisetron is 5-HT₃R antagonists with a K_i of 5.3 nM. Tropisetron is also a partial agonist of α7 nicotinic receptor (α7 nAChR) with an EC₅₀ of 1.3 μM. In addition, Tropisetron has antitumor and neuroprotective effects .

HY-W041194R

Tropic acid (Standard) DL-tropic acid (Standard)	Reference Standards Drug Intermediate	Others
Tropic acid (DL-Tropic acid) is an active small molecule that can be used as the pharmaceutical intermediate .

HY-Y0135R

Tropinone (Standard)	Drug Intermediate Reference Standards	Neurological Disease
Tropinone (Standard) is the analytical standard of Tropinone. This product is intended for research and analytical applications. Tropinone, an alkaloid, acts as a synthetic intermediate to Atropine .

HY-N7061R

Tropine (Standard)	Reference Standards Drug Intermediate	Neurological Disease
Tropine (Standard) is the analytical standard of Tropine (HY-N7061). This product is intended for research and analytical applications. Tropine is a tropane alkaloid. Tropine serves as an important intermediate for the synthesis of anticholinergics and bronchodilators such as Atropine (HY-B1205) and Scopolamine (HY-N0296) .

HY-163687

Tropirine BS-7723 free base	Biochemical Assay Reagents	Cancer
Tropirine (BS-7723 free base) is a radiosensitizer. Tropirine can be used in cancer research .

HY-B0321R

Tropicamide (Standard) Ro 1-7683 (Standard)	Reference Standards mAChR	Neurological Disease
Tropicamide (Standard) is the analytical standard of Tropicamide. This product is intended for research and analytical applications. Tropicamide (Ro 1-7683) is a selective M4 muscarinic acetylcholine receptor antagonist. Tropicamide produces short acting mydriasis (dilation of the pupil) and cycloplegia when applied as eye drops .

HY-B0020R

Tropisetron Hydrochloride (Standard) SDZ-ICS-930 (Standard)	5-HT Receptor Reference Standards nAChR	Neurological Disease Cancer
Tropisetron (Hydrochloride) (Standard) is the analytical standard of Tropisetron (Hydrochloride). Tropisetron Hydrochloride (SDZ-ICS-930) is an effective neuroprotective agent that acts as a 5-HT3 receptor antagonist, a calmodulin inhibitor, and an α7-nAChRreceptor agonist, with an IC₅₀ of 70.1 nM for the 5-HT3 receptor. Tropisetron Hydrochloride has anti-inflammatory properties and immune-regulating functions, effectively alleviating symptoms associated with chemotherapy and post-surgery. Tropisetron Hydrochloride reduces Ab (HY-P4867)-induced hippocampal neuroinflammation .

HY-101314

3-CPMT tropine 4-chlorobenzhydryl ether hydrochloride	Dopamine Transporter	Neurological Disease
3-CPMT (Tropine 4-chlorobenzhydryl ether hydrochloride) is a potent dopamine uptake inhibitor . 3-CPMT (Tropine 4-chlorobenzhydryl ether hydrochloride) acts as a potent long-acting antihistaminic agent .

HY-B1205B

Atropine hydrobromide tropine tropate hydrobromide; DL-Hyoscyamine hydrobromide	mAChR	Cardiovascular Disease Neurological Disease Cancer
Atropine (Tropine tropate) hydrobromide is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC₅₀ values of 0.39 and 0.71 nM for Human mAChR M₄ and Chicken mAChR M₄, respectively. Atropine hydrobromide inhibits ACh-induced relaxations in human pulmonary veins. Atropine hydrobromide can be used for research of anti-myopia and bradycardia .

HY-B0394R

Atropine sulfate monohydrate (Standard) tropine tropate sulfate monohydrate (Standard); DL-Hyoscyamine sulfate monohydrate (Standard)	Reference Standards mAChR	Cardiovascular Disease Neurological Disease
Atropine (sulfate monohydrate) (Standard) is the analytical standard of Atropine (sulfate monohydrate). This product is intended for research and analytical applications. Atropine (Tropine tropate) sulfate monohydrate is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC₅₀ values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine sulfate monohydrate inhibits ACh-induced relaxations in human pulmonary veins. Atropine sulfate monohydrate can be used for research of anti-myopia and bradycardia .

HY-107418R

Tropifexor (Standard) LJN452 (Standard)	Reference Standards FXR Autophagy	Cardiovascular Disease
Tropifexor (Standard) is the analytical standard of Tropifexor (HY-107418). This product is intended for research and analytical applications. Tropifexor (LJN452) is a highly potent agonist of FXR with an EC₅₀ of 0.2 nM .

HY-W033010R

Pseudotropine (Standard) β-tropine (Standard)	Drug Derivative Reference Standards	Others
Pseudotropine (Standard) is the analytical standard of Pseudotropine (HY-W033010). This product is intended for research and analytical applications. Pseudotropine (β-Tropine), a derivative of Tropane, is a plant alkaloid .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B1205

Atropine 20+ Cited Publications tropine tropate; DL-Hyoscyamine	Alkaloids Structural Classification Other Alkaloids Atropa belladonna Linn. Solanaceae Plants Endogenous metabolite Source Classification	Environmental Pollutants Endogenous Metabolite mAChR
Atropine (Tropine tropate) is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC₅₀ values of 0.39 and 0.71 nM for Human mAChR M₄ and Chicken mAChR M₄, respectively. Atropine inhibits ACh-induced relaxations in human pulmonary veins. Atropine can be used for research of anti-myopia and bradycardia .

HY-W041194

Tropic acid DL-tropic acid	Microorganisms other families Ketones, Aldehydes, Acids Other Diseases Plants Disease Research Fields Source Classification	Drug Intermediate
Tropic acid (DL-Tropic acid) is an active small molecule that can be used as the pharmaceutical intermediate .

HY-N7061

Tropine	Alkaloids Other Alkaloids Solanaceae Plants Przewalskia tangutica Maximo. Source Classification	Drug Intermediate
Tropine is a tropane alkaloid. Tropine serves as an important intermediate for the synthesis of anticholinergics and bronchodilators such as Atropine (HY-B1205) and Scopolamine (HY-N0296) .

HY-B1205R

Atropine (Standard) tropine tropate (Standard); DL-Hyoscyamine (Standard)	Atropa belladonna Linn. Solanaceae Plants Endogenous metabolite Source Classification	Reference Standards mAChR Endogenous Metabolite
Atropine (Standard) is the analytical standard of Atropine. This product is intended for research and analytical applications. Atropine (Tropine tropate) is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC₅₀ values of 0.39 and 0.71 nM for Human mAChR M₄ and Chicken mAChR M₄, respectively. Atropine inhibits ACh-induced relaxations in human pulmonary veins. Atropine can be used for research of anti-myopia and bradycardia .

HY-B1205AR

Atropine sulfate (Standard) tropine tropate sulfate (Standard); DL-Hyoscyamine sulfate (Standard); Sulfatropinol (Standard)	Alkaloids Structural Classification Other Alkaloids Atropa belladonna Linn. Solanaceae Plants Source Classification	Reference Standards mAChR
Atropine (sulfate) (Standard) is the analytical standard of Atropine (sulfate). This product is intended for research and analytical applications. Atropine (Tropine tropate) sulfate is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC50 values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine sulfate inhibits ACh-induced relaxations in human pulmonary veins. Atropine sulfate can be used for research of anti-myopia and bradycardia .

HY-W033010

Pseudotropine β-tropine	Alkaloids Classification of Application Fields Erythroxylaceae Other Alkaloids Other Diseases Plants Disease Research Fields Erythroxylum coca Lam. Source Classification	Drug Derivative
Pseudotropine (β-Tropine), a derivative of Tropane, is a plant alkaloid .

HY-W041194R

Tropic acid (Standard) DL-tropic acid (Standard)	Microorganisms other families Ketones, Aldehydes, Acids Plants Source Classification	Reference Standards Drug Intermediate
Tropic acid (DL-Tropic acid) is an active small molecule that can be used as the pharmaceutical intermediate .

HY-N7061R

Tropine (Standard)	Alkaloids Structural Classification Microorganisms Other Alkaloids Solanaceae Plants Przewalskia tangutica Maximo. Source Classification	Reference Standards Drug Intermediate
Tropine (Standard) is the analytical standard of Tropine (HY-N7061). This product is intended for research and analytical applications. Tropine is a tropane alkaloid. Tropine serves as an important intermediate for the synthesis of anticholinergics and bronchodilators such as Atropine (HY-B1205) and Scopolamine (HY-N0296) .

HY-B0394R

Atropine sulfate monohydrate (Standard) tropine tropate sulfate monohydrate (Standard); DL-Hyoscyamine sulfate monohydrate (Standard)	Alkaloids Structural Classification Other Alkaloids Atropa belladonna Linn. Solanaceae Plants Source Classification	Reference Standards mAChR
Atropine (sulfate monohydrate) (Standard) is the analytical standard of Atropine (sulfate monohydrate). This product is intended for research and analytical applications. Atropine (Tropine tropate) sulfate monohydrate is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC₅₀ values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine sulfate monohydrate inhibits ACh-induced relaxations in human pulmonary veins. Atropine sulfate monohydrate can be used for research of anti-myopia and bradycardia .

HY-W033010R

Pseudotropine (Standard) β-tropine (Standard)	Alkaloids Structural Classification Erythroxylaceae Other Alkaloids Plants Erythroxylum coca Lam. Source Classification	Drug Derivative Reference Standards
Pseudotropine (Standard) is the analytical standard of Pseudotropine (HY-W033010). This product is intended for research and analytical applications. Pseudotropine (β-Tropine), a derivative of Tropane, is a plant alkaloid .

Tag:	His (5)
Source:	HEK293 (2) P. pastoris (2) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P77304

	BLOT1 Protein, Blomia tropicalis (P.pastoris, His) Type 2 allergen Blo t 2.047	Others	P. pastoris
	BLOT1 Protein, Blomia tropicalis (P.pastoris, His) is the recombinant BLOT1 protein, expressed by P. pastoris, with N-6*His labeled tag.

HY-P77305

	BLOT2 Protein, Blomia tropicalis (HEK293, His) Type 2 allergen Blo t 2.047	Others	HEK293
	BLOT1 Protein is a Blomia tropicalis allergen and is highly homologous to cysteine proteases. BLOT1 may play a major role as an immunodominant allergen involved in dust mite-specific IgE-mediated hypersensitivity. BLOT1, like the other group 1 HDM allergens, is a digestive enzyme associated with mite fecal pellets. BLOT2 Protein, Blomia tropicalis (HEK293, His) is the recombinant BLOT2 protein, expressed by HEK293 , with N-6*His labeled tag.

HY-P76748

	BLOT5 Protein, Blomia tropicalis (P.pastoris, His) Mite allergen Blo t 5; Allergen: Blo t 5	Others	P. pastoris
	BLOT5 protein exhibits potential homodimeric and homotrimeric forms and is detected in midgut and hindgut contents as well as fecal pellets. Its presence suggests a role in different physiological processes within these regions. BLOT5 Protein, Blomia tropicalis (P.pastoris, His) is the recombinant BLOT5 protein, expressed by P. pastoris , with C-His labeled tag.

HY-P77306

	Blot21 Protein, Blomia tropicalis (His) Mite allergen Blo t 21; Mite group 21 allergen Blo t 21; Blo t 21	Others	E. coli
	Blot21 Protein, representing a new group of allergens, is an important Blomia tropicalis allergen. Allergenic components from Blomia tropicalis are important triggers of allergies in the tropics. Blot21 is a paralog of the group 5 allergen Blot5. Blot21 has moderate sequence identity (40.7%) to Blot5 and low to moderate cross-reactivity to Blot5. Blot21 Protein, Blomia tropicalis (His) is the recombinant Blot21 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P77307

	Blot21 Protein, Blomia tropicalis (HEK293, His) Mite allergen Blo t 21; Mite group 21 allergen Blo t 21; Blo t 21	Others	HEK293
	Blot21 Protein, representing a new group of allergens, is an important Blomia tropicalis allergen. Allergenic components from Blomia tropicalis are important triggers of allergies in the tropics. Blot21 is a paralog of the group 5 allergen Blot5. Blot21 has moderate sequence identity (40.7%) to Blot5 and low to moderate cross-reactivity to Blot5. Blot21 Protein, Blomia tropicalis (HEK293, His) is the recombinant Blot21 protein, expressed by HEK293 , with N-6*His labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-B0394S

Atropine-d5
Atropine-d₅ is the deuterium labeled Atropine (sulfate monohydrate). Atropine (Tropine tropate) sulfate monohydrate is a broad-spectrum and competitive muscarinic acetylcholine receptor (mAChR) antagonist with anti-myopia effect .

HY-B0321S

Tropicamide-d3
Tropicamide-d₃ is the deuterium labeled Tropicamide . Tropicamide (Ro 1-7683) is a selective M4 muscarinic acetylcholine receptor antagonist. Tropicamide produces short acting mydriasis (dilation of the pupil) and cycloplegia when applied as eye drops .

HY-B1205S

(Rac)-Atropine-d3 1 Publications Verification
(Rac)-Atropine-d₃ is the deuterium labeled (Rac)-Atropine[1].

HY-B0072S

Tropisetron-d5

Tropisetron-d₅ (SDZ-ICS-930-d₅ (free base)) is deuterium labeled Tropisetron. Tropisetron (SDZ-ICS-930 free base) is an orally active anti-inflammatory and antiemetic agent. Tropisetron is 5-HT₃R antagonists with a K_i of 5.3 nM. Tropisetron is also a partial agonist of α7 nicotinic receptor (α7 nAChR) with an EC₅₀ of 1.3 μM. In addition, Tropisetron has antitumor and neuroprotective effects .

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