2. Antibody-drug Conjugate/ADC Related Cytoskeleton
  3. Antibody-Drug Conjugates (ADCs) Integrin
  4. Sigvotatug vedotin

Sigvotatug vedotin  (Synonyms: SGN-B6A; PF-08046047)

Cat. No.: HY-164957 Pureté: 99.0%
COA
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SGN-B6A is an ADC, which targets integrin beta-6 (ITGB6) through human IgG1 monoclonal antibody Sigvotatug (HY-P990764), and exhibits cytotoxicity against multiple integrin beta-6-positive cancer cell through mitotic inhibitor MMAE (HY-15162).

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Sigvotatug vedotin

Sigvotatug vedotin Chemical Structure

CAS No. : 2764774-91-4

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Sigvotatug vedotin Related Antibodies

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αvβ1 αvβ3 αvβ5 αvβ6 αvβ8 α5β1 α1β1 α2β1 α4β1 α9β1 αIIbβ3 α4β7 αLβ2

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Description

SGN-B6A is an ADC, which targets integrin beta-6 (ITGB6) through human IgG1 monoclonal antibody Sigvotatug (HY-P990764), and exhibits cytotoxicity against multiple integrin beta-6-positive cancer cell through mitotic inhibitor MMAE (HY-15162)[1].

Essai clinique
Masse moléculaire

150000 (average)

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Sigvotatug vedotin]
Livraison

Shipping with dry ice.
Stockage

-80°C, protect from light
Pureté et documentation

Purity: 99.68%

SDS (251 KB)

COA (231 KB) Others (191 KB) SEC-HPLC (186 KB)

Instruction de manipulation (2659 KB)
Références
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Sigvotatug vedotin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sigvotatug vedotin2764774-91-4SGN-B6A PF-08046047PF08046047PF 08046047PF-08046047Antibody-Drug Conjugates (ADCs)IntegrinAntibody-Drug ConjugatesBXPC3SW780NSCLCInhibitorinhibitorinhibit

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