2. Anti-infection
  3. Bacterial Antibiotic
  4. Dicloxacillin Sodium hydrate

Dicloxacillin (Sodium hydrate)  (Synonyms: Dicloxacillin sodium salt monohydrate; ジクロキサシリンナトリウム水和物)

製品番号: HY-B0977 純度: 98.94%
COA 取扱説明書 Technical Support

Dicloxacillin Sodium hydrate (Dicloxacillin sodium salt monohydrate) is a narrow-spectrum β-Lactam antibiotic of the penicillin class, is used to treat infections caused by susceptible Gram-positive bacteria, active against beta-lactamase-producing organisms such as Staphylococcus aureus.

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Dicloxacillin Sodium hydrate

Dicloxacillin (Sodium hydrate) 構造式

CAS 番号 : 13412-64-1

容量 価格（税別） 在庫状況 数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
 USD 28 在庫あり
Solution
10 mM * 1 mL in Water USD 28 在庫あり
Solid
5 mg $25 在庫あり
10 mg $35 在庫あり
25 mg $45 在庫あり
50 mg $60 在庫あり
100 mg $85 在庫あり
200 mg   お問い合わせ  
500 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

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Based on 3 publication(s) in Google Scholar

Other Forms of Dicloxacillin Sodium hydrate:

Dicloxacillin (Sodium hydrate) 関連抗体

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製品説明

Dicloxacillin Sodium hydrate (Dicloxacillin sodium salt monohydrate) is a narrow-spectrum β-Lactam antibiotic of the penicillin class, is used to treat infections caused by susceptible Gram-positive bacteria, active against beta-lactamase-producing organisms such as Staphylococcus aureus[1][2][3].

IC50 & Target

β-lactam

 

体外実験

Dicloxacillin exhibits EC50 values of 0.06 and 0.50 mg/L in ATCC 25923 and E19977, respectively. Dicloxacillin exhibits MIC values of 0.125 and 0.5 mg/L in ATCC 25923 and E19977 with pH 7.4, respectively[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Dicloxacillin (Sodium hydrate) 関連抗体

Cell Viability Assay[3]

Cell Line: Strains ATCC 25923 and E19977.
Concentration: 0-500 mg/L.
Incubation Time: Up to 24 h.
Result: Exhibited EC50 values of 0.06 and 0.50 mg/L in ATCC 25923 and E19977, respectively.
体内実験

Dicloxacillin exhibits therapeutic activity in murine peritonitis-sepsis model and all the mice are survivied[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female outbred Swiss Webster mice (Murine peritonitis-sepsis model)[4].
Dosage: 125 mg/kg.
Administration: IV injection, single doses.
Result: All the mice survived.
分子量

510.32

分子式

C19H18Cl2N3NaO6S
CAS 番号
Appearance

Solid

Color

White to off-white

SMILES

O=C(O[Na])[C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC(C3=C(C)ON=C3C4=C(Cl)C=CC=C4Cl)=O)N1C2=O.O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
体外: 

H2O : 25 mg/mL (48.99 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9596 mL 9.7978 mL 19.5955 mL
5 mM 0.3919 mL 1.9596 mL 3.9191 mL
10 mM 0.1960 mL 0.9798 mL 1.9596 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

体内:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 25 mg/mL (48.99 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
純度とドキュメンテーション

純度: 98.94%

COA (263 KB) HNMR (166 KB) LCMS (276 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.9596 mL 9.7978 mL 19.5955 mL 48.9889 mL
5 mM 0.3919 mL 1.9596 mL 3.9191 mL 9.7978 mL
10 mM 0.1960 mL 0.9798 mL 1.9596 mL 4.8989 mL
15 mM 0.1306 mL 0.6532 mL 1.3064 mL 3.2659 mL
20 mM 0.0980 mL 0.4899 mL 0.9798 mL 2.4494 mL
25 mM 0.0784 mL 0.3919 mL 0.7838 mL 1.9596 mL
30 mM 0.0653 mL 0.3266 mL 0.6532 mL 1.6330 mL
40 mM 0.0490 mL 0.2449 mL 0.4899 mL 1.2247 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dicloxacillin Sodium hydrate Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dicloxacillin Sodium13412-64-1Dicloxacillin sodium saltBacterialAntibioticperitonitissepsisInhibitorinhibitorinhibit

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製品名:
Dicloxacillin Sodium hydrate
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