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  4. L-Serine

Serine  (Synonyms: L-Serine; L-セリン)

製品番号: HY-N0650 純度: 99.95%
COA 取扱説明書 Technical Support

L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

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CAS 番号 : 56-45-1

容量 価格（税別） 在庫状況 数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
 USD 33 在庫あり
Solution
10 mM * 1 mL in Water USD 33 在庫あり
Solid
500 mg $30 在庫あり
1 g $40 在庫あり
5 g   お問い合わせ  
10 g   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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カスタマーレビュー

Based on 13 publication(s) in Google Scholar

Other Forms of L-Serine:

Serine 関連抗体

Top Publications Citing Use of Products

    L-Serine purchased from MedChemExpress. Usage Cited in: Ecotoxicol Environ Saf. 2024 Nov 1:286:117216.  [Abstract]

    L-serine (50 g/L; drinking water administration). Immunohistochemical staining of CD68 (macrophage marker).

    L-Serine purchased from MedChemExpress. Usage Cited in: Ecotoxicol Environ Saf. 2024 Jul 2:281:116678.  [Abstract]

    L-serine (300 mg/kg; i.v.). Immunofluorescence staining of Ly6G and citH3 in different groups of liver tissues.

    L-Serine purchased from MedChemExpress. Usage Cited in: Ecotoxicol Environ Saf. 2024 Jul 2:281:116678.  [Abstract]

    L-serine (300 mg/kg; i.v.). Changes of Cleaved-Caspase 3, NETs formation-associated proteins citH3 and MPO, ERK/p38 signaling pathway proteins in different groups.

    L-Serine purchased from MedChemExpress. Usage Cited in: Ecotoxicol Environ Saf. 2024 Jul 2:281:116678.  [Abstract]

    L-serine (300 mg/kg; i.v.). qRT-PCR was applied for determine the expression of TNF-α in different groups.

    L-Serine purchased from MedChemExpress. Usage Cited in: Ecotoxicol Environ Saf. 2024 Jul 2:281:116678.  [Abstract]

    L-serine (300 mg/kg; i.v.). DNA content in serum of different groups of mice.

    Endogenous Metabolite アイソフォーム固有の製品をすべて表示:

    すべてのアイソフォームを表示
    Human Endogenous Metabolite Microbial Metabolite

    • 生物活性

    • 純度とドキュメンテーション

    • 参考文献

    • カスタマーレビュー

    製品説明

    L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

    IC50 & Target

    Microbial Metabolite

     

    Human Endogenous Metabolite

     

    体外実験

    L-Serine is the predominant source of one-carbon groups for the de novo synthesis of purine nucleotides and deoxythymidine monophosphate. In cell cultures, L-Serine is a conditionally essential amino acid, because it cannot be synthesized in sufficient quantities to meet the cellular demands for its utilization.L-Serine and the products of its metabolism have been recognized not only to be essential for cell proliferation but also to be necessary for specific functions in the central nervous system[1].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Serine 関連抗体
    臨床実験
    分子量

    105.09

    分子式

    C3H7NO3
    CAS 番号
    Appearance

    Solid

    Color

    White to off-white

    SMILES

    N[C@@H](CO)C(O)=O
    Structure Classification
    Initial Source
    輸送条件

    Room temperature in continental US; may vary elsewhere.
    保管条件

    Store at room temperature 3 years

    *In solvent : -80°C, 6 months; -20°C, 1 month (Store at room temperature 3 years)
    溶剤 & 溶解度
    体外: 

    H2O : 50 mg/mL (475.78 mM; Need ultrasonic)

    Methanol : < 1 mg/mL (insoluble)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 9.5157 mL 47.5783 mL 95.1565 mL
    5 mM 1.9031 mL 9.5157 mL 19.0313 mL
    10 mM 0.9516 mL 4.7578 mL 9.5157 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

    • Molarity Calculator

    • Dilution Calculator

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    Mass
    =
    Concentration
    ×
    Volume
    ×
    Molecular Weight *

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    一般には略語で表示されます：C1V1 = C2V2

    濃度 （開始）

    C1

    ×
    体積 （開始）

    V1

    =
    濃度 （終了）

    C2

    ×
    体積 （終了）

    V2

    体内:

    For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
    The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

    • Protocol 1

      Add each solvent one by one:  PBS

      Solubility: 100 mg/mL (951.57 mM); Clear solution; Need ultrasonic

    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

    Dosage

    mg/kg

    Animal weight
    (per animal)

    g

    Dosing volume
    (per animal)

    μL

    Number of animals

    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Calculation results:
    Working solution concentration: mg/mL
    This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
    純度とドキュメンテーション

    純度: 99.95%

    COA (246 KB) HNMR (115 KB) RP-HPLC (239 KB) MS (81 KB)

    取扱説明書 (2659 KB)
    参考文献

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    H2O 1 mM 9.5157 mL 47.5783 mL 95.1565 mL 237.8913 mL
    5 mM 1.9031 mL 9.5157 mL 19.0313 mL 47.5783 mL
    10 mM 0.9516 mL 4.7578 mL 9.5157 mL 23.7891 mL
    15 mM 0.6344 mL 3.1719 mL 6.3438 mL 15.8594 mL
    20 mM 0.4758 mL 2.3789 mL 4.7578 mL 11.8946 mL
    25 mM 0.3806 mL 1.9031 mL 3.8063 mL 9.5157 mL
    30 mM 0.3172 mL 1.5859 mL 3.1719 mL 7.9297 mL
    40 mM 0.2379 mL 1.1895 mL 2.3789 mL 5.9473 mL
    50 mM 0.1903 mL 0.9516 mL 1.9031 mL 4.7578 mL
    60 mM 0.1586 mL 0.7930 mL 1.5859 mL 3.9649 mL
    80 mM 0.1189 mL 0.5947 mL 1.1895 mL 2.9736 mL
    100 mM 0.0952 mL 0.4758 mL 0.9516 mL 2.3789 mL

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    L-Serine Related Classifications

    • Molarity Calculator

    • Dilution Calculator

    The molarity calculator equation

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    質量   濃度   体積   分子量 *
    = × ×

    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    一般には略語で表示されます：C1V1 = C2V2

    濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
    × = ×
    C1   V1   C2   V2
    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    L-Serine56-45-1SerineEndogenous MetaboliteBacterialInhibitorinhibitorinhibit

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