L-Serine-d3
Based on 2 publication(s) in Google Scholar
L-Serine-d3 is the deuterium labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.
For research use only. We do not sell to patients.
- Purity: 99.75%
- CAS No.: 105591-10-4
- Formula: C3H4D3NO3
- Molecular Weight:108.11
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) L-Serine-d3
MoreAll Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 105591-10-4
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Unlabeled Cas 56-45-1
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Appearance Solid
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Molecular Weight 108.11
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Formula C3H4D3NO3
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Color White to off-white
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SMILES
OC([C@](N)([2H])C([2H])([2H])O)=O
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Synonyms
(-)-Serine-d3; (S)-Serine-d3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (2)
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Journal Impact Factor
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Most Recent
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Nat Struct Mol Biol
RNAi screens identify HES4 as a regulator of redox balance supporting pyrimidine synthesis and tumor growth. [Abstract]2024 May 20. PMID: 38769389 -
Proc Natl Acad Sci U S A
The oncoprotein SET promotes serine-derived one-carbon metabolism by regulating SHMT2 enzymatic activity. [Abstract]2025 May 13;122(19):e2412854122. PMID: 40339130
Solvent & Solubility
H2O : 125 mg/mL (1156.23 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 50 mg/mL (462.49 mM); Clear solution; Need ultrasonic
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 9.2498 mL | 46.2492 mL | 92.4984 mL | 231.2460 mL |
| 5 mM | 1.8500 mL | 9.2498 mL | 18.4997 mL | 46.2492 mL | |
| 10 mM | 0.9250 mL | 4.6249 mL | 9.2498 mL | 23.1246 mL | |
| 15 mM | 0.6167 mL | 3.0833 mL | 6.1666 mL | 15.4164 mL | |
| 20 mM | 0.4625 mL | 2.3125 mL | 4.6249 mL | 11.5623 mL | |
| 25 mM | 0.3700 mL | 1.8500 mL | 3.6999 mL | 9.2498 mL | |
| 30 mM | 0.3083 mL | 1.5416 mL | 3.0833 mL | 7.7082 mL | |
| 40 mM | 0.2312 mL | 1.1562 mL | 2.3125 mL | 5.7811 mL | |
| 50 mM | 0.1850 mL | 0.9250 mL | 1.8500 mL | 4.6249 mL | |
| 60 mM | 0.1542 mL | 0.7708 mL | 1.5416 mL | 3.8541 mL | |
| 80 mM | 0.1156 mL | 0.5781 mL | 1.1562 mL | 2.8906 mL | |
| 100 mM | 0.0925 mL | 0.4625 mL | 0.9250 mL | 2.3125 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
L-Serine-d3 Related Classifications
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