2. Metabolic Enzyme/Protease Anti-infection
  3. Endogenous Metabolite Bacterial
  4. L-Serine

L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

For research use only. We do not sell to patients.

CAS No. : 56-45-1

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in Water In-stock
Solid
500 mg In-stock
1 g In-stock
5 g   Get quote  
10 g   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 13 publication(s) in Google Scholar

Other Forms of L-Serine:

L-Serine Related Antibodies

Top Publications Citing Use of Products

    L-Serine purchased from MedChemExpress. Usage Cited in: Ecotoxicol Environ Saf. 2024 Nov 1:286:117216.  [Abstract]

    L-serine (50 g/L; drinking water administration). Immunohistochemical staining of CD68 (macrophage marker).

    L-Serine purchased from MedChemExpress. Usage Cited in: Ecotoxicol Environ Saf. 2024 Jul 2:281:116678.  [Abstract]

    L-serine (300 mg/kg; i.v.). Immunofluorescence staining of Ly6G and citH3 in different groups of liver tissues.

    L-Serine purchased from MedChemExpress. Usage Cited in: Ecotoxicol Environ Saf. 2024 Jul 2:281:116678.  [Abstract]

    L-serine (300 mg/kg; i.v.). Changes of Cleaved-Caspase 3, NETs formation-associated proteins citH3 and MPO, ERK/p38 signaling pathway proteins in different groups.

    L-Serine purchased from MedChemExpress. Usage Cited in: Ecotoxicol Environ Saf. 2024 Jul 2:281:116678.  [Abstract]

    L-serine (300 mg/kg; i.v.). qRT-PCR was applied for determine the expression of TNF-α in different groups.

    L-Serine purchased from MedChemExpress. Usage Cited in: Ecotoxicol Environ Saf. 2024 Jul 2:281:116678.  [Abstract]

    L-serine (300 mg/kg; i.v.). DNA content in serum of different groups of mice.

    View All Endogenous Metabolite Isoform Specific Products:

    View All Isoforms
    Human Endogenous Metabolite Microbial Metabolite

    • Biological Activity

    • Purity & Documentation

    • References

    • Customer Review

    Description

    L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

    IC50 & Target

    Microbial Metabolite

     

    Human Endogenous Metabolite

     

    In Vitro

    L-Serine is the predominant source of one-carbon groups for the de novo synthesis of purine nucleotides and deoxythymidine monophosphate. In cell cultures, L-Serine is a conditionally essential amino acid, because it cannot be synthesized in sufficient quantities to meet the cellular demands for its utilization.L-Serine and the products of its metabolism have been recognized not only to be essential for cell proliferation but also to be necessary for specific functions in the central nervous system[1].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    L-Serine Related Antibodies
    Clinical Trial
    Molecular Weight

    105.09

    Formula

    C3H7NO3
    CAS No.
    Appearance

    Solid

    Color

    White to off-white

    SMILES

    N[C@@H](CO)C(O)=O
    Structure Classification
    Initial Source
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    Store at room temperature 3 years

    In solvent -80°C 2 years
    -20°C 1 year
    Solvent & Solubility
    In Vitro: 

    H2O : 50 mg/mL (475.78 mM; Need ultrasonic)

    Methanol : < 1 mg/mL (insoluble)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 9.5157 mL 47.5783 mL 95.1565 mL
    5 mM 1.9031 mL 9.5157 mL 19.0313 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

    • Molarity Calculator

    • Dilution Calculator

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    Mass
    =
    Concentration
    ×
    Volume
    ×
    Molecular Weight *

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start)

    C1

    ×
    Volume (start)

    V1

    =
    Concentration (final)

    C2

    ×
    Volume (final)

    V2

    In Vivo:

    For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
    The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

    • Protocol 1

      Add each solvent one by one:  PBS

      Solubility: 100 mg/mL (951.57 mM); Clear solution; Need ultrasonic

    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

    Dosage

    mg/kg

    Animal weight
    (per animal)

    g

    Dosing volume
    (per animal)

    μL

    Number of animals

    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Calculation results:
    Working solution concentration: mg/mL
    This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
    Purity & Documentation

    Purity: 99.95%

    SDS (393 KB)

    COA (246 KB) HNMR (115 KB) RP-HPLC (239 KB) MS (81 KB)

    Handling Instructions (2659 KB)
    References

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    H2O 1 mM 9.5157 mL 47.5783 mL 95.1565 mL 237.8913 mL
    5 mM 1.9031 mL 9.5157 mL 19.0313 mL 47.5783 mL
    10 mM 0.9516 mL 4.7578 mL 9.5157 mL 23.7891 mL
    15 mM 0.6344 mL 3.1719 mL 6.3438 mL 15.8594 mL
    20 mM 0.4758 mL 2.3789 mL 4.7578 mL 11.8946 mL
    25 mM 0.3806 mL 1.9031 mL 3.8063 mL 9.5157 mL
    30 mM 0.3172 mL 1.5859 mL 3.1719 mL 7.9297 mL
    40 mM 0.2379 mL 1.1895 mL 2.3789 mL 5.9473 mL
    50 mM 0.1903 mL 0.9516 mL 1.9031 mL 4.7578 mL
    60 mM 0.1586 mL 0.7930 mL 1.5859 mL 3.9649 mL
    80 mM 0.1189 mL 0.5947 mL 1.1895 mL 2.9736 mL
    100 mM 0.0952 mL 0.4758 mL 0.9516 mL 2.3789 mL

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

    • No file chosen (Maximum size is: 1024 Kb)
    • If you have published this work, please enter the PubMed ID.
    • Your name will appear on the site.

    L-Serine Related Classifications

    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    L-Serine56-45-1SerineEndogenous MetaboliteBacterialInhibitorinhibitorinhibit

    Your Recently Viewed Products:

    Inquiry Online

    Your information is safe with us. * Required Fields.

    Product Name

    		  

    Requested Quantity *

    Applicant Name *

    		 

    Salutation

    Email Address *

    		 

    Phone Number *

    Department

    		 

    Organization Name *

    City

    State

    Country or Region *

    		      

    Remarks

    Bulk Inquiry

    Inquiry Information

    Product Name:
    L-Serine
    Cat. No.:
    HY-N0650
    Quantity:
    MCE Japan Authorized Agent:

    Customer Review

    Thank You for Your Feedback!

    Request for HNMR Report

    Please fill out this form to request the QC report. We will send it to your Email address shortly.

    Your information is safe with us. * Required Fields.

    Product Name

    		  

    Lot #

    Applicant Name *

    		 

    Email Address *

    Phone Number

    		 

    Department *

    Organization Name *

    		 

    Country or Region *

    Remarks

    SAFETY DATA SHEET (SDS)

    English - EN (393 KB) Français - FR (393 KB) Deutsch - DE (393 KB) Norwegian - NO (393 KB) Español - ES (393 KB) Swedish - SV (393 KB) Italian - IT (393 KB) Korean - KR (393 KB) Portuguese - PT (393 KB)

    Request for HNMR Report

    We have received your request and will respond to you as soon as possible.