2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. 상품명 CAS No. Purity 화학구조
  • HY-17520
    Penthiopyrad 183675-82-3 ≥98.0%
    Penthiopyrad (MTF-753) is a carboxamide Fungicide. Penthiopyrad inhibits SDH. Penthiopyrad exhibits broad-spectrum antifungal activity, being effective not only against Basidiomycetes, but also against Ascomycetes and Deuteromycetes. Penthiopyrad inhibits the mycelial growth of Alternaria mali, Botrytis cinerea, Monilinia mali, Rhizoctonia solani and Sclerotinia sclerotiorum on PDA medium, with EC50 values ranging from <0.4 ppm to 0.34 ppm and MIC values ranging from 6.6 ppm to 47.9 ppm.
    Penthiopyrad
  • HY-145119
    GS-621763 2647442-13-3 99.72%
    GS-621763 is an orally available precursor to GS-441524 that exhibits anti-SARS-CoV-2 viral activity in mice. GS-621763 reduces viral load to undetectable levels in ferrets infected with SARS-CoV-2.
    GS-621763
  • HY-15141G
    Staurosporine (GMP) 62996-74-1 98%
    Staurosporine (AM-2282) (GMP) is Staurosporine (HY-15141) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Staurosporine is a potent, ATP-competitive and non-selective inhibitor of protein kinases.
    Staurosporine (GMP)
  • HY-Y0248AS
    (E,​E)​-​Farnesol-d6 166447-71-8 98.71%
    (E,​E)​-​Farnesol-d6 (trans,trans-Farnesol-d6) is deuterium labeled (E,​E)​-​Farnesol (HY-Y0248). (E,E)-Farnesol (trans,trans-Farnesol) is a quorum-sensing molecule of Candida species. (E,E)-Farnesol can inhibit the growth, metabolism and biofilm formation of various Candida species, and affect their morphology and invasiveness.
    (E,​E)​-​Farnesol-d6
  • HY-17425
    Valacyclovir 124832-26-4 98.50%
    Valacyclovir (Valaciclovir) is an orally active antiviral agent for herpes simplex, herpes zoster, and herpes B. Valacyclovir inhibits HSV-1 W (50=2.9 μg/ml). Valacyclovir is a proagent of Aciclovir (HY-17422) .
    Valacyclovir
  • HY-19743
    Triazavirin 928659-17-0 99.89%
    Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent. Triazavirin works by inhibiting the synthesis of viral RNA and DNA and replication of genomic fragments. Triazavirin is also an effective protective agent on the transmission stage of influenza.
    Triazavirin
  • HY-100531
    DprE1-IN-2 1615713-87-5 98.94%
    DprE1-IN-2 (compound 18) is a potent DprE1 inhibitor with an IC50 of 28 nM. DprE1-IN-2 has antituberculosis effect.
    DprE1-IN-2
  • HY-101866
    KKL-35 865285-29-6 99.46%
    KKL-35 is a trans-translation tagging reaction inhibitor with an IC50 of 0.9 μM.
    KKL-35
  • HY-111023
    Nemonoxacin malate 951163-60-3 99.29%
    Nemonoxacin (TG-873870) malate is a nonfluorinated quinolone antibiotic. Nemonoxacin malate has broad-spectrum activity against Gram-positive, Gram-negative and atypical pathogens. Nemonoxacin malate can inhibit drug-resistant Streptococcus pneumoniae and Methicillin-resistant Staphylococcus aureus. Nemonoxacin malate can be used for the research of community-acquired pneumonia.
    Nemonoxacin malate
  • HY-111759
    Jaspamycin 22242-96-2 98.94%
    Jaspamycin (7-CN-7-C-Ino) is a potent activator of PKA, binding to the R site (PKAR), with an EC50 of 6.5 nM and Kd of 8 nM in Trypanosoma brucei. Jaspamycin (7-CN-7-C-Ino) does not bind with purified human PKARIα. Anti-parasite activity.
    Jaspamycin
  • HY-114314
    BA-53038B 2306195-65-1 98.73%
    BA-53038B is a HBV core protein allosteric modulator (CpAM), binding to the HAP pocket and modulating HBV capsid assembly. BA-53038B has antiviral activity for hepatitis B virus (HBV) with an EC50 value of 3.32 μM. BA-53038B can be used for the research of chronic hepatitis B.
    BA-53038B
  • HY-135327
    Amphotericin B methyl ester 36148-89-7
    Amphotericin B methyl ester is the methyl ester derivative of the polyene antibiotic Amphotericin B (A634250). Amphotericin B methyl ester is the cholesterol-binding compound possesses significant antifungal activity. Amphotericin B methyl ester disrupts HIV-1 particle production and potently inhibits HIV-1 replication.
    Amphotericin B methyl ester
  • HY-144300
    Rifasutenizol 1001314-13-1 99.53%
    Rifasutenizol (TNP-2198) is a dual-targeted antibacterial agent that has a good antibacterial effect on Helicobacter pylori infection. Rifasutenizol can be used in the study of microaerophilic and anaerobic bacterial infections.
    Rifasutenizol
  • HY-144645
    SP-471P 2768011-36-3 99.46%
    SP-471P is a potent dengue virus (DENV) protease inhibitor with EC50s of 5.9 μM, 1.4 μM, 5.1 μM and 1.7 μM for DENV1, DENV2, DENV3 and DENV4, respectively and CC50 value over 100 μM. SP-471P can reduce DENV viral RNA synthesis.
    SP-471P
  • HY-101954A
    Inarigivir ammonium 2172788-92-8 99.04%
    Inarigivir (ORI-9020) ammonium is a dinucleotide antiviral drug that can significantly reduce liver HBV DNA in transgenic mice expressing hepatitis B virus. Inarigivir (ORI-9020) ammonium acts as a RIG-I (Retinoic acid-inducible gene-I) agonist to activate cellular innate immune responses.
    Inarigivir ammonium
  • HY-15005S1
    Sofosbuvir-d6 1868135-06-1
    Sofosbuvir-d6 is the deuterium labeled Sofosbuvir. Sofosbuvir (PSI-7977) is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity.
    Sofosbuvir-d6
  • HY-B0458
    Cefprozil monohydrate 121123-17-9 99.86%
    Cefprozil monohydrate is a second-generation cephalosporin type antibiotic. Cefprozil monohydrate exhibits broad-spectrum antibacterial activity, and is orally active. Cefprozil monohydrate can be used for the study of pharyngitis, tonsillitis, otitis media, and uncomplicated skin infections.
    Cefprozil monohydrate
  • HY-106268
    Larazotide 258818-34-7 99.26%
    Larazotideis a peptide which is an orally active zonulin antagonist. Larazotide shows antiviral activity to varicella-zoster virus (VZV) with EC50s of 44.14 and 59.06 μM for strain OKA and 07-1, respectively. Larazotide can be used for the research of celiac disease and infection.
    Larazotide
  • HY-152851
    Izumerogant 2299252-72-3 99.95%
    Izumerogant (IMU-935) is an orally active RORγ/DHODH dual inhibitor with IC50s of 10 and 98 nM against RORγ and DHODH. Izumerogant efficiently blocks the replication of SARS-CoV-2, HCMV and HAdV5 with EC50 values between 3.6 and 17 nM. Izumerogant can be used for researching antiviral properties.
    Izumerogant
  • HY-P0052A
    Enfuvirtide acetate 914454-00-5 99.95%
    Enfuvirtide (T20; DP178) acetate is an anti-HIV-1 fusion inhibitor peptide.
    Enfuvirtide acetate
Cat. No. 상품명 / Synonyms Application Reactivity