1. Anti-infection
  2. HIV
  3. Enfuvirtide acetate

Enfuvirtide acetate 

Cat. No.: HY-P0052A
Handling Instructions

Enfuvirtide acetate is an anti-HIV-1 fusion inhibitor peptide.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Enfuvirtide acetate Chemical Structure

Enfuvirtide acetate Chemical Structure

Size Price Stock Quantity
5 mg USD 72 In-stock
Estimated Time of Arrival: December 31
10 mg USD 108 In-stock
Estimated Time of Arrival: December 31
25 mg USD 228 In-stock
Estimated Time of Arrival: December 31
50 mg USD 408 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

Other Forms of Enfuvirtide acetate:

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Description

Enfuvirtide acetate is an anti-HIV-1 fusion inhibitor peptide.

IC50 & Target

HIV fusion[1]

In Vitro

A cell-cell fusion assay reveals that the effective concentration for achieving 50% inhibition (IC50) of Enfuvirtide is 23 ± 6 nM[2]. IFN-λs (1, 2, or 3) or the antiretrovirals (AZT, Efavirenz, Indinavir, and Enfuvirtide) significantly inhibita the expression of HIV p24 antigen and Gag gene in macrophages. IFN-λs (1, 2, or 3) also enhanced the anti-HIV (Bal) effect of AZT, Efavirenz, Indinavir, and Enfuvirtide[3].

In Vivo

Enfuvirtide has a T1/2 of 3.8 h[2].

Molecular Weight

4551.93

Formula

C₂₀₆H₃₀₅N₅₁O₆₆

Sequence

Ac-Tyr-Thr-Ser-Leu-Ile-His-Ser-Leu-Ile-Glu-Glu-Ser-Gln-Asn-Gln-Gln-Glu-Lys-Asn-Glu-Gln-Glu-Leu-Leu-Glu-Leu-Asp-Lys-Trp-Ala-Ser-Leu-Trp-Asn-Trp-Phe-NH2

Sequence Shortening

Ac-YTSLIHSLIEESQNQQEKNEQELLELDKWASLWNWF-NH2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

EnfuvirtideHIVHuman immunodeficiency virusInhibitorinhibitorinhibit

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Enfuvirtide acetate
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HY-P0052A
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