1. Anti-infection
  2. HIV
    Fungal
  3. Amphotericin B methyl ester

Amphotericin B methyl ester 

Cat. No.: HY-135327
Handling Instructions

Amphotericin B methyl ester is the methyl ester derivative of the polyene antibiotic Amphotericin B (A634250). Amphotericin B methyl ester is the cholesterol-binding compound possesses significant antifungal activity. Amphotericin B methyl ester disrupts HIV-1 particle production and potently inhibits HIV-1 replication.

For research use only. We do not sell to patients.

Amphotericin B methyl ester Chemical Structure

Amphotericin B methyl ester Chemical Structure

CAS No. : 36148-89-7

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Description

Amphotericin B methyl ester is the methyl ester derivative of the polyene antibiotic Amphotericin B (A634250). Amphotericin B methyl ester is the cholesterol-binding compound possesses significant antifungal activity. Amphotericin B methyl ester disrupts HIV-1 particle production and potently inhibits HIV-1 replication[1][2].

In Vitro

Amphotericin B methyl ester inhibits HIV-1 particle production with no significant effect on Gag binding to the plasma membrane, Gag association with lipid rafts, or Gag multimerization[1].

Molecular Weight

938.11

Formula

C₄₈H₇₅NO₁₇

CAS No.

36148-89-7

SMILES
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Amphotericin B methyl esterHIVFungalHuman immunodeficiency virusderivativecholesterol-bindingantifungalreplicationInhibitorinhibitorinhibit

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Amphotericin B methyl ester
Cat. No.:
HY-135327
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