Rifasutenizol
Based on 1 Customer Validation
Rifasutenizol (TNP-2198) is a dual-targeted antibacterial agent that has a good antibacterial effect on Helicobacter pylori infection. Rifasutenizol can be used in the study of microaerophilic and anaerobic bacterial infections.
For research use only. We do not sell to patients.
- Purity: 99.53%
- CAS No.: 1001314-13-1
- Formula: C48H61N7O13
- Molecular Weight:944.04
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Rifasutenizol exhibits potent bactericidal activity against key microaerophilic and anaerobic bacterial pathogens, including Helicobacter pylori, Clostridioides difficile, and Gardnerella vaginalis, including rifamycin-resistant and nitroimidazole-resistant strains[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 1001314-13-1
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Appearance Solid
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Molecular Weight 944.04
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Formula C48H61N7O13
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Color Colorless to off-white
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SMILES
O=C(C)O[C@H]1[C@H](C)[C@H](O)[C@H](C)[C@@H](O)[C@@H](C)/C=C/C=C(C(NC(C(C2=C3C4=C(O[C@](C)(O/C=C/[C@H](OC)[C@H]1C)C4=O)C(C)=C2O)=O)=C5C3=NC6(CCN(CCN7C([N+]([O-])=O)=CN=C7C)CC6)N5)=O)/C
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Synonyms
TNP-2198
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (274 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Ma Z, et al. Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. J Med Chem. 2022;65(6):4481-4495. [Content Brief]
[2]. Li X, et al. Safety, pharmacokinetics, and efficacy of rifasutenizol, a novel dual-targeted antibacterial agent in healthy participants and patients in China with Helicobacter pylori infection: four randomised clinical trials[J]. The Lancet Infectious Diseases, 2024, 24(6): 650-664. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Rifasutenizol Related Classifications
HY-144300 Related Classifications
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