2. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor
  3. ROR
  4. Izumerogant

Izumerogant (IMU-935) is an inverse agonist of retinoid-related orphan receptor-gamma (RORγ). Izumerogant (compound 123) also potently inhibits IL-17A, IL-17F and IFN-γ activity with IC50s <50 nM.

For research use only. We do not sell to patients.

Izumerogant Chemical Structure

Izumerogant Chemical Structure

CAS No. : 2299252-72-3

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Izumerogant Related Antibodies

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Description

Izumerogant (IMU-935) is an inverse agonist of retinoid-related orphan receptor-gamma (RORγ). Izumerogant (compound 123) also potently inhibits IL-17A, IL-17F and IFN-γ activity with IC50s <50 nM[1][2].

Clinical Trial
Molecular Weight

495.86

Formula

C22H18ClF4N5O2
CAS No.
SMILES

FC1=CC=CC(Cl)=C1C2=NOC(C3=C(C(F)(F)F)N(CCC(C)(C)O)N=C3)=C2C4=NC=CC=N4
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Izumerogant Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Izumerogant2299252-72-3IMU-935IMU935IMU 935RORRAR-related orphan receptorInhibitorinhibitorinhibit

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