RORγ/DHODH-IN-2
RORγ/DHODH-IN-2 (Compound 1311) is an orally active dual inhibitor of RORγ/DHODH with IC50 values of 11.9 nM and 90 nM, respectively. RORγ/DHODH-IN-2 exhibits antiviral activity by inhibiting the activity of SARS-CoV-2, HCMV, HAdV5, and MPXV, with IC50 values of 27 nM, 20 nM, 9.1 nM, and 1.8 nM, respectively.
For research use only. We do not sell to patients.
- CAS No.: 3000567-45-0
- Formula: C22H16D2ClF4N5O2
- Molecular Weight:497.87
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 3000567-45-0
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Unlabeled Cas 2299252-72-3
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Molecular Weight 497.87
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Formula C22H16D2ClF4N5O2
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SMILES
ClC1=C(C(F)=CC=C1)C2=NOC(C3=C(N(N=C3)C([2H])(CC(C)(C)O)[2H])C(F)(F)F)=C2C4=NC=CC=N4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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