2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-14837
    Amizon 201349-37-3 99.92%
    Amizon is an orally effective antiviral and anti-inflammatory agent. Amizon inhibits influenza virus replication and restricts viral RNA synthesis. Amizon reduces the mRNA expression of COX-1, COX-2, NF-κB, TGF1β, IL-1 and IL-6, and stimulates the secretion and mRNA expression of IL-10. Amizon inhibits the oxidative activity of macrophages and possesses antioxidant and free radical-scavenging activities. Amizon is applicable to research related to influenza and acute respiratory viral infections.
    Amizon
  • HY-15134
    ONT-093 216227-54-2 99.21%
    ONT-093 (OC 144-093) is a potent and orally active inhibitor of P-glycoprotein pump. ONT-093 inhibits P-gp-mediated ATPase activity with an IC50 of 0.16 μM. ONT-093 can inhibit drug efflux and increase bioavailability. ONT-093 reverses cancer cells multidrug resistance to chemotherapeutic drugs. ONT-093 can be used for the researches of cancer and infection, such as colon cancer and malarial .
    ONT-093
  • HY-15353
    Emivirine 149950-60-7 99.73%
    Emivirine (MKC-442) is a non-nucleoside reverse transcriptase inhibitors (NNRTIs) with Ki values of 0.20 and 0.01 μM for dTTP- and dGTP-dependent DNA or RNA polymerase activity, respectively. Emivirine displays potent and selective anti-human immunodeficiency virus type 1 (HIV-1) activity.
    Emivirine
  • HY-15379
    Atevirdine 136816-75-6 98.69%
    Atevirdine is a potent non-nucleoside HIV-1 reverse transcriptase inhibitor. Atevirdine inhibits non-nucleoside reverse transcriptase that leads to viral multiplication.
    Atevirdine
  • HY-16137
    Cefaloglycin 3577-01-3
    Cefaloglycin (Cephaloglycin) is an orally active nephrotoxic β-lactam cephalosporin antibiotic with antibacterial activity. Cefaloglycin is activity against Gram-Positive cocci other than enterococci. Cefaloglycin is toxic to mitochondrial substrate uptake and respiration.
    Cefaloglycin
  • HY-16719
    Dapaconazole 1269726-67-1 99.76%
    Dapaconazole, as an antifungal agent, inhibits sterol 14α-demethylase cytochrome P450 activity with an IC50 of 1.4 μM.
    Dapaconazole
  • HY-16784
    Samatasvir 1312547-19-5 99.39%
    Samatasvir (IDX71) is a potent, orally active NS5A inhibitor of HCV replication. Samatasvir is effective and selective against infectious HCV and replicons, with EC50s falling within a tight range of 2 to 24 pM in genotype 1 through 5 replicons.
    Samatasvir
  • HY-17532
    Haloxon 321-55-1 98.0%
    Haloxon is an anti-parasitic agent. Haloxon can be used for the research of infections of Parascaris equorum, Oxyuris equi and Strongylus vulgaris. Haloxon also can be used in control of ascarids and hookworms in domesticated animals in combination with Bidimazium.
    Haloxon
  • HY-17597
    Febantel 58306-30-2 99.91%
    Febantel is an oral dewormer used to treat gastrointestinal nematodes in sheep, as well as roundworm and tapeworm infections in poultry and livestock, and it also inhibits the embryonic development of mouse hairworms and whipworm eggs.
    Febantel
  • HY-18169
    MUT056399 1269055-85-7 99.87%
    MUT056399 (Fab-001) is a highly potent inhibitor of the FabI enzyme of both S. aureus and E. coli with 50% inhibitory concentration IC50s of 12 nM and 58 nM, respectively.
    MUT056399
  • HY-18598
    Chitinase-IN-1 1579991-61-9 98.04%
    Chitinase-IN-1 is an insecticide that can inhibit the activity of chitinase and N-acetylglucosaminidase. The inhibition percentages for glycosidase and N-acetylglucosaminidase at concentrations of 50 uM and 20 uM are 75% and 67%, respectively.
    Chitinase-IN-1
  • HY-19285
    Sulfaclozine 102-65-8 99.0%
    Sulfaclozine (Sulfachloropyrazine) is an efficacious sulphonamide derivative with antibacterial and anticoccidial effects. Sulfaclozine is commonly used for the treatment of various poultry diseases (particularly, collibacteriosis, fowl cholera and coccidiosis).
    Sulfaclozine
  • HY-19509
    IQP-0528 301297-45-0 99.90%
    IQP-0528 is a highly potent nonnucleoside reverse transcriptase inhibitor (NNRTI). IQP-0528 shows nanomolar activity against both HIV-1 and HIV-2, with EC50s of 0.2 nM and 100 nM, respectively.
    IQP-0528
  • HY-19827
    Aeroplysinin 1 28656-91-9
    Aeroplysinin 1 ((+)-Aeroplysinin-1), a secondary metabolite isolated from marine sponges, shows potent antibiotic effects on Gram-positive bacteria and exerts antiviral activity against HIV-1 (IC50=14.6 μM). Aeroplysinin 1 has anti-inflammatory, anti-angiogenic and anti-tumor activities. Aeroplysinin 1 induces apoptosis in endothelial cells.
    Aeroplysinin 1
  • HY-76212
    ATB107 455325-51-6 99.36%
    ATB107 is a potent inhibitor of indole-3-glycerol phosphate synthase (IGPS) with a KD of 3 μM.
    ATB107
  • HY-A0246
    Flucloxacillin 5250-39-5 98.02%
    Flucloxacillin is an active antibiotic against gram-positive and gram-negative bacteria.
    Flucloxacillin
  • HY-B0026
    Ceftiofur hydrochloride 103980-44-5 98.43%
    Ceftiofur hydrochloride is a cell wall synthesis inhibitor that targets bacterial penicillin-binding proteins (PBPs) and has anti-inflammatory effects in endotoxemia. Ceftiofur hydrochloride exerts bactericidal effects by inhibiting the synthesis of bacterial cell wall peptidoglycan, leading to bacterial cell lysis. Ceftiofur hydrochloride also inhibits the activation of NF-κB and MAPKs, thereby reducing the secretion of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6.
    Ceftiofur hydrochloride
  • HY-B0501
    Danofloxacin mesylate 119478-55-6 99.88%
    Danofloxacin mesylate (CP 76136-27) is a fluoroquinolone used as a veterinary drug. Danofloxacin mesylate has a broad spectrum of bactericidal activity, mainly inhibiting the DNA cycloenzyme of the bacteria. In addition, Danofloxacin mesylate is a substrate for ATP-dependent efflux transporters (P-gp and MRP2).
    Danofloxacin mesylate
  • HY-B1147
    Diloxanide furoate 3736-81-0 99.80%
    Diloxanide furoate is the proagent of Diloxanide. Diloxanide furoate is a potent and orally active anti-protozoal agent and can be used for the research of amebiasis, mild intestinal amebiasis or asymptomatic cyst carriers.
    Diloxanide furoate
  • HY-B1252
    Cefalonium 5575-21-3 98.85%
    Cefalonium is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci.
    Cefalonium
Cat. No. Product Name / Synonyms Application Reactivity