1. Signaling Pathways
  2. Neuronal Signaling
  3. Cholinesterase (ChE)
  4. AChE Isoform
  5. AChE Inhibitor

AChE Inhibitor

AChE Inhibitors (80):

Cat. No. Product Name Effect Purity
  • HY-107569
    Inhibitor 98.85%
    Garcinol, a polyisoprenylated benzophenone harvested from Garcinia indica, exerts anti-cholinesterase properties towards acetyl cholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50s of 0.66 µM and 7.39 µM, respectively.
  • HY-108477
    TMPyP4 tosylate
    Inhibitor ≥98.0%
    TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand.
  • HY-76299
    Inhibitor 99.96%
    Galanthamine is a potent acetylcholinesterase (AChE) inhibitor with an IC50 of 500 nM.
  • HY-N0342
    Inhibitor 99.70%
    Scopoletin is an inhibitor of acetylcholinesterase (AChE).
  • HY-17387
    (-)-Huperzine A
    Inhibitor 99.00%
    (-)-Huperzine A (Huperzine A) is an alkaloid isolated from Huperzia serrata, with neuroprotective activity.
  • HY-10399A
    Ladostigil hydrochloride
    Ladostigil (TV-3326) hydrochloride is an orally active dual inhibitor of cholinesterase and brain-selective monoamine oxidase (MAO), with IC50s of 37.1 and 31.8 μM for MAO-B and AChE, respectively.
  • HY-151927
    AChE-IN-28 (Compound 2h) is a selective slow-binding inhibitor of acetylcholinesterase with an IC50 of 0.2 nM.
  • HY-152113
    AChE/BChE/MAO-B-IN-3, an indan-1-one derivative, is a potent MAO-B inhibitor with an IC50 of 0.0359 μM for human MAO-B.
  • HY-B0949
    Protriptyline hydrochloride
    Inhibitor 99.91%
    Protriptyline hydrochloride is a tricyclic antidepressant (TCA), specifically a secondary amine, for the treatment of depression and ADHD.
  • HY-N2181
    Inhibitor 98.10%
    Acetylshikonin, derived from the root of Lithospermum erythrorhizon, has anti-cancer and antiinflammation activity.
  • HY-N0285
    Inhibitor 98.00%
    Imperatorin is an effective of NO synthesis inhibitor (IC50=9.2 μmol), which also is a BChE inhibitor (IC50=31.4 μmol).
  • HY-75247
    Inhibitor 99.54%
    Coumaran (2,3-Dihydrobenzofuran) is an acetylcholinesterase (AChE) inhibitor isolated from leaves of L.
  • HY-N5077
    Inhibitor 99.72%
    Sinapine is an alkaloid isolated from seeds of the cruciferous species.
  • HY-16009
    Inhibitor 98.09%
    Buntanetap ((+)-Phenserine) is a novel selective cholinesterase noncompetitive inhibitor with an IC50 of 45.3 μM.
  • HY-N0450
    Sinapine thiocyanate
    Inhibitor 99.74%
    Sinapine thiocyanate is an alkaloid isolated from seeds of the cruciferous species.
  • HY-N0226A
    Epiberberine chloride
    Inhibitor 99.03%
    Epiberberine chloride is an alkaloid isolated from Coptis chinensis, acts as a potent AChE and BChE inhibitor, and a non-competitive BACE1 inhibitor, with IC50s of 1.07, 6.03 and 8.55 μM, respectively.
  • HY-N0528
    Inhibitor ≥98.0%
    Linarin (Buddleoside), isolated from the flower extract of Mentha arvensis, shows selective dose dependent inhibitory effect on acetylcholinesterase (AChE).
  • HY-N0286
    Inhibitor 98.93%
    Isoimperatorin is a methanolic extract of the roots of Angelica dahurica shows significant inhibitory effects on acetylcholinesterase (AChE) with the IC50 of 74.6 μM.
  • HY-N4142
    Cyanidin-3-O-galactoside chloride
    Inhibitor 99.87%
    Cyanidin-3-O-galactoside chloride (Ideain chloride) is a component from extract peel of hawthorn fruit (EPHF) with the value of 179.4 mg/g.
  • HY-N0923
    Inhibitor 98.44%
    Corydaline ((+)-Corydaline), an isoquinoline alkaloid isolated from Corydalis yanhusuo, is an AChE inhibitor with an IC50 of 226 µM.