1. Cell Cycle/DNA Damage
  2. G-quadruplex
    Telomerase
  3. TMPyP4 tosylate

TMPyP4 tosylate (Synonyms: TMP 1363)

Cat. No.: HY-108477 Purity: >98.0%
Handling Instructions

TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand, which inhibits the interaction between G-quadruplexes and IGF-1. TMPyP4 tosylate (TMP 1363) is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.

For research use only. We do not sell to patients.

TMPyP4 tosylate Chemical Structure

TMPyP4 tosylate Chemical Structure

CAS No. : 36951-72-1

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Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand, which inhibits the interaction between G-quadruplexes and IGF-1[1]. TMPyP4 tosylate (TMP 1363) is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines[2].

IC50 & Target

G-quadruplex[2]
Telomerase[2]

Molecular Weight

1363.60

Formula

C₇₂H₆₆N₈O₁₂S₄

CAS No.

36951-72-1

SMILES

C[N+]1=CC=C(/C2=C3C=CC(/C(C4=CC=[N+](C)C=C4)=C5C=C/C(N/5)=C(C6=CC=[N+](C)C=C6)/C(C=C/7)=NC7=C(C8=CC=[N+](C)C=C8)/C9=CC=C2N9)=N\3)C=C1.O=S(C%10=CC=C(C)C=C%10)([O-])=O.O=S(C%11=CC=C(C)C=C%11)([O-])=O.O=S(C%12=CC=C(C)C=C%12)([O-])=O.O=S(C%13=CC=C(C)C=C%13)([O-])=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 6.2 mg/mL (4.55 mM; Need ultrasonic)

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Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.7334 mL 3.6668 mL 7.3335 mL
5 mM --- --- ---
10 mM --- --- ---
*Please refer to the solubility information to select the appropriate solvent.
References
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TMPyP4 tosylate
Cat. No.:
HY-108477
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