1. Neuronal Signaling
  2. AChE
  3. Chlorpyrifos

Chlorpyrifos 

Cat. No.: HY-B0815
Handling Instructions

Chlorpyrifos is an organophosphate insecticide that is classified as a phosphorothionate. The oxon metabolite of Chlorpyrifos is an inhibitor of acetylcholinesterase (AChE), affecting neurological function in insects, humans, and other animals. The Chlorpyrifos oxon (CPO) metabolite is hydrolyzed by the plasma enzyme paraoxonase 1 (PON1), and susceptibility to neurotoxicity associated with CPO exposure is mitigated by PON1 overexpression.

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Chlorpyrifos Chemical Structure

Chlorpyrifos Chemical Structure

CAS No. : 2921-88-2

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Description

Chlorpyrifos is an organophosphate insecticide that is classified as a phosphorothionate. The oxon metabolite of Chlorpyrifos is an inhibitor of acetylcholinesterase (AChE), affecting neurological function in insects, humans, and other animals. The Chlorpyrifos oxon (CPO) metabolite is hydrolyzed by the plasma enzyme paraoxonase 1 (PON1), and susceptibility to neurotoxicity associated with CPO exposure is mitigated by PON1 overexpression.

Molecular Weight

350.59

Formula

C₉H₁₁Cl₃NO₃PS

CAS No.

2921-88-2

SMILES

S=P(OCC)(OCC)OC1=NC(Cl)=C(Cl)C=C1Cl

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Keywords:

ChlorpyrifosAChEAcetylcholinesteraseInhibitorinhibitorinhibit

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