1. Neuronal Signaling
  2. AChE
  3. Chlorpyrifos

Chlorpyrifos 

Cat. No.: HY-B0815 Purity: >98.0%
Handling Instructions

Chlorpyrifos is an organophosphate insecticide that is classified as a phosphorothionate. The oxon metabolite of Chlorpyrifos is an inhibitor of acetylcholinesterase (AChE), affecting neurological function in insects, humans, and other animals. The Chlorpyrifos oxon (CPO) metabolite is hydrolyzed by the plasma enzyme paraoxonase 1 (PON1), and susceptibility to neurotoxicity associated with CPO exposure is mitigated by PON1 overexpression.

For research use only. We do not sell to patients.

Chlorpyrifos Chemical Structure

Chlorpyrifos Chemical Structure

CAS No. : 2921-88-2

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50 mg USD 55 In-stock
Estimated Time of Arrival: December 31
100 mg USD 75 In-stock
Estimated Time of Arrival: December 31
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Description

Chlorpyrifos is an organophosphate insecticide that is classified as a phosphorothionate. The oxon metabolite of Chlorpyrifos is an inhibitor of acetylcholinesterase (AChE), affecting neurological function in insects, humans, and other animals. The Chlorpyrifos oxon (CPO) metabolite is hydrolyzed by the plasma enzyme paraoxonase 1 (PON1), and susceptibility to neurotoxicity associated with CPO exposure is mitigated by PON1 overexpression.

Molecular Weight

350.59

Formula

C₉H₁₁Cl₃NO₃PS

CAS No.

2921-88-2

SMILES

S=P(OCC)(OCC)OC1=NC(Cl)=C(Cl)C=C1Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (713.08 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8523 mL 14.2617 mL 28.5233 mL
5 mM 0.5705 mL 2.8523 mL 5.7047 mL
10 mM 0.2852 mL 1.4262 mL 2.8523 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 6.25 mg/mL (17.83 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 6.25 mg/mL (17.83 mM); Clear solution

*All of the co-solvents are provided by MCE.
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

ChlorpyrifosAChEAcetylcholinesteraseInhibitorinhibitorinhibit

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Product Name:
Chlorpyrifos
Cat. No.:
HY-B0815
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