i-Inositol (Synonyms: myo-Inositol; meso-Inositol)

Name: i-Inositol
Brand: MedChemExpress
SKU: HY-B1411
Rating: 5.0 (6 reviews)

Cat. No.: HY-B1411 Pureza: 98.0%: Ficha de datos
COA

SDS
Instrucciones de manejo
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i-Inositol (myo-Inositol) is a compound of sugar alcohols. i-Inositol is involved in a series of biological processes such as insulin signal transduction and cytoskeletal transduction. i-Inositol mainly exists in glial cells and plays an osmotic role.

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No. CAS : 87-89-8

Tamaño	Stock	Cantidad
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	En stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	En stock	Estimated Time of Arrival: December 31
Solid
500 mg	En stock	Estimated Time of Arrival: December 31
5 g	En stock	Estimated Time of Arrival: December 31
10 g	Obtener un presupuesto
50 g	Obtener un presupuesto

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Revisión del cliente

Based on 6 publication(s) in Google Scholar

Other Forms of i-Inositol:

6 Publications Citing Use of MCE i-Inositol

Cell Proliferation/Viability Assay

Cell Imaging/Staining

: i-Inositol purchased from MedChemExpress. Usage Cited in: Theriogenology. 2025 Dec:248:117594. [Abstract]; Effect of myo-Inositol (Myo; 25 mM) on ROS and GSH levels in oocytes. Images of staining of ROS and GSH levels.

: i-Inositol purchased from MedChemExpress. Usage Cited in: Theriogenology. 2025 Dec:248:117594. [Abstract]; Effect of myo-Inositol (Myo; 25 mM) on Ca²⁺ levels in oocytes. Representative images of Ca²⁺ level in the control and myo-Inositol groups.

: i-Inositol purchased from MedChemExpress. Usage Cited in: Biochem Biophys Res Commun. 2024 May 9:719:150027. [Abstract]; myo-Inositol (MI; 0.5-20 mM; 48 h). Therapeutic concentrations of GS were detected by CCK8.

: i-Inositol purchased from MedChemExpress. Usage Cited in: Biochem Biophys Res Commun. 2024 May 9:719:150027. [Abstract]; myo-Inositol (MI; 0.5-20 mM; 48 h). Immunofluorescence staining of ROS (green signal) was detected in aging HL-1 cells (200 ×).

: i-Inositol purchased from MedChemExpress. Usage Cited in: Biochem Biophys Res Commun. 2024 May 9:719:150027. [Abstract]; myo-Inositol (MI; 0-2 mM; 48 h). Aging cells were marked blue by β-galactosidase staining.

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Ver todos los productos específicos de isoformas Endogenous Metabolite:

Ver todas las isoformas

Human Endogenous Metabolite Microbial Metabolite

Actividad biológica
Pureza y Documentación
Referencias
Revisión del cliente

Descripciòn

IC₅₀ & Target

Human Endogenous Metabolite

In Vitro

i-Inositol (2 mg/mL, 2 h) can improve sperm mitochondrial function in patients with altered sperm parameters^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Ensayo clínico

Peso molecular

180.16

Fòrmula

C₆H₁₂O₆

No. CAS

87-89-8

Appearance

Solid

Color

White to light yellow

SMILES

O[C@H]1[C@H]([C@H]([C@@H]([C@H]([C@@H]1O)O)O)O)O

Structure Classification

Others

Initial Source

Microorganisms

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Store at room temperature 3 years

In solvent	-80°C	2 years
	-20°C	1 year

Solvente y solubilidad

In Vitro:

H₂O : 62.5 mg/mL (346.91 mM; ultrasonic and warming and heat to 60°C)

DMSO : 10 mg/mL (55.51 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.5506 mL	27.7531 mL	55.5062 mL
5 mM	1.1101 mL	5.5506 mL	11.1012 mL
10 mM	0.5551 mL	2.7753 mL	5.5506 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Calculadora de molaridad
Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 1 mg/mL (5.55 mM); Clear solution

This protocol yields a clear solution of ≥ 1 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (10.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 1 mg/mL (5.55 mM); Clear solution

This protocol yields a clear solution of ≥ 1 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (10.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 100 mg/mL (555.06 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Pureza y Documentación

Purity: ≥99.0%

Select Batch:

Ficha de datos (278 KB) SDS (393 KB)

COA (254 KB)

Instrucciones de manejo (2659 KB)

Referencias

[1]. Condorelli RA, et al. Effects of myoinositol on sperm mitochondrial function in-vitro. Eur Rev Med Pharmacol Sci. 2011 Feb;15(2):129-34. [Content Brief]

[2]. Haris M, et al. In vivo mapping of brain myo-inositol. Neuroimage. 2011 Feb 1;54(3):2079-85. [Content Brief]

[3]. Paquette AF, et al. The human milk component myo-inositol promotes neuronal connectivity. Proc Natl Acad Sci U S A. 2023 Jul 25;120(30):e2221413120. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / H₂O	1 mM	5.5506 mL	27.7531 mL	55.5062 mL	138.7655 mL
	5 mM	1.1101 mL	5.5506 mL	11.1012 mL	27.7531 mL
	10 mM	0.5551 mL	2.7753 mL	5.5506 mL	13.8766 mL
	15 mM	0.3700 mL	1.8502 mL	3.7004 mL	9.2510 mL
	20 mM	0.2775 mL	1.3877 mL	2.7753 mL	6.9383 mL
	25 mM	0.2220 mL	1.1101 mL	2.2202 mL	5.5506 mL
	30 mM	0.1850 mL	0.9251 mL	1.8502 mL	4.6255 mL
	40 mM	0.1388 mL	0.6938 mL	1.3877 mL	3.4691 mL
	50 mM	0.1110 mL	0.5551 mL	1.1101 mL	2.7753 mL
H₂O	60 mM	0.0925 mL	0.4626 mL	0.9251 mL	2.3128 mL
	80 mM	0.0694 mL	0.3469 mL	0.6938 mL	1.7346 mL
	100 mM	0.0555 mL	0.2775 mL	0.5551 mL	1.3877 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

i-Inositol Related Classifications

Others

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

i-Inositol87-89-8myo-Inositol meso-InositolEndogenous Metabolitemyo-inositolOligo-astheno-teratozoospermia (OAT)SpermInhibitorinhibitorinhibit

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i-Inositol (Synonyms: myo-Inositol; meso-Inositol)

Revisión del cliente

Other Forms of i-Inositol:

i-Inositol Related Antibodies

6 Publications Citing Use of MCE i-Inositol

Recomendaciones destacadas

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Ver todos los productos específicos de isoformas Endogenous Metabolite:

Actividad biológica

Pureza y Documentación

Referencias

Revisión del cliente

i-Inositol Related Antibodies

Calculadora de molaridad

Calculadora de dilución

Complete Stock Solution Preparation Table

i-Inositol Related Classifications

Keywords:

Productos vistos recientemente:

Revisión del cliente

Request for HNMR Report

SAFETY DATA SHEET (SDS)

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