2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. i-Inositol

i-Inositol  (Synonyms: myo-Inositol; meso-Inositol)

Cat. No.: HY-B1411 Pureté: 98.0%
COA
SDS
Instruction de manipulation Technical Support

i-Inositol (myo-Inositol) is a compound of sugar alcohols. i-Inositol is involved in a series of biological processes such as insulin signal transduction and cytoskeletal transduction. i-Inositol mainly exists in glial cells and plays an osmotic role.

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CAS No. : 87-89-8

Size Prix Stock Quantité
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 En stock
Solution
10 mM * 1 mL in DMSO En stock
Solid
500 mg En stock
5 g En stock
10 g   Obtenir un devis  
50 g   Obtenir un devis  

* Veuillez sélectionner la quantité avant d'ajouter des articles.

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Based on 6 publication(s) in Google Scholar

Other Forms of i-Inositol:

i-Inositol Related Antibodies

Top Publications Citing Use of Products

    i-Inositol purchased from MedChemExpress. Usage Cited in: Theriogenology. 2025 Dec:248:117594.  [Abstract]

    Effect of myo-Inositol (Myo; 25 mM) on ROS and GSH levels in oocytes. Images of staining of ROS and GSH levels.

    i-Inositol purchased from MedChemExpress. Usage Cited in: Theriogenology. 2025 Dec:248:117594.  [Abstract]

    Effect of myo-Inositol (Myo; 25 mM) on Ca2+ levels in oocytes. Representative images of Ca2+ level in the control and myo-Inositol groups.

    i-Inositol purchased from MedChemExpress. Usage Cited in: Biochem Biophys Res Commun. 2024 May 9:719:150027.  [Abstract]

    myo-Inositol (MI; 0.5-20 mM; 48 h). Therapeutic concentrations of GS were detected by CCK8.

    i-Inositol purchased from MedChemExpress. Usage Cited in: Biochem Biophys Res Commun. 2024 May 9:719:150027.  [Abstract]

    myo-Inositol (MI; 0.5-20 mM; 48 h). Immunofluorescence staining of ROS (green signal) was detected in aging HL-1 cells (200 ×).

    i-Inositol purchased from MedChemExpress. Usage Cited in: Biochem Biophys Res Commun. 2024 May 9:719:150027.  [Abstract]

    myo-Inositol (MI; 0-2 mM; 48 h). Aging cells were marked blue by β-galactosidase staining.

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    Description

    i-Inositol (myo-Inositol) is a compound of sugar alcohols. i-Inositol is involved in a series of biological processes such as insulin signal transduction and cytoskeletal transduction. i-Inositol mainly exists in glial cells and plays an osmotic role[1][2][3].

    IC50 & Target

    Human Endogenous Metabolite

     

    In Vitro

    i-Inositol (2 mg/mL, 2 h) can improve sperm mitochondrial function in patients with altered sperm parameters[1].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    i-Inositol Related Antibodies
    Essai clinique
    Masse moléculaire

    180.16

    Formule

    C6H12O6
    CAS No.
    Appearance

    Solid

    Color

    White to light yellow

    SMILES

    O[C@H]1[C@H]([C@H]([C@@H]([C@H]([C@@H]1O)O)O)O)O
    Structure Classification
    Initial Source
    Livraison

    Room temperature in continental US; may vary elsewhere.
    Stockage

    Store at room temperature 3 years

    In solvent -80°C 2 years
    -20°C 1 year
    Solvant et solubilité
    In Vitro: 

    H2O : 62.5 mg/mL (346.91 mM; ultrasonic and warming and heat to 60°C)

    DMSO : 10 mg/mL (55.51 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 5.5506 mL 27.7531 mL 55.5062 mL
    5 mM 1.1101 mL 5.5506 mL 11.1012 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

    • Calculateur de molarité

    • Calculateur de dilution

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    Mass
    =
    Concentration
    ×
    Volume
    ×
    Molecular Weight *

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start)

    C1

    ×
    Volume (start)

    V1

    =
    Concentration (final)

    C2

    ×
    Volume (final)

    V2

    In Vivo:

    Select the appropriate dissolution method based on your experimental animal and administration route.

    For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
    To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
    The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

    • Protocol 1

      Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

      Solubility: ≥ 1 mg/mL (5.55 mM); Clear solution

      This protocol yields a clear solution of ≥ 1 mg/mL (saturation unknown).

      Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (10.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

      Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
    • Protocol 2

      Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

      Solubility: ≥ 1 mg/mL (5.55 mM); Clear solution

      This protocol yields a clear solution of ≥ 1 mg/mL (saturation unknown).

      Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (10.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

      Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.

    For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
    The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

    • Protocol 1

      Add each solvent one by one:  PBS

      Solubility: 100 mg/mL (555.06 mM); Clear solution; Need ultrasonic

    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

    Dosage

    mg/kg

    Animal weight
    (per animal)

    g

    Dosing volume
    (per animal)

    μL

    Number of animals

    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Calculation results:
    Working solution concentration: mg/mL
    This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
    Pureté et documentation

    Purity: ≥99.0%

    SDS (393 KB)

    COA (254 KB)

    Instruction de manipulation (2659 KB)
    Références

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    DMSO / H2O 1 mM 5.5506 mL 27.7531 mL 55.5062 mL 138.7655 mL
    5 mM 1.1101 mL 5.5506 mL 11.1012 mL 27.7531 mL
    10 mM 0.5551 mL 2.7753 mL 5.5506 mL 13.8766 mL
    15 mM 0.3700 mL 1.8502 mL 3.7004 mL 9.2510 mL
    20 mM 0.2775 mL 1.3877 mL 2.7753 mL 6.9383 mL
    25 mM 0.2220 mL 1.1101 mL 2.2202 mL 5.5506 mL
    30 mM 0.1850 mL 0.9251 mL 1.8502 mL 4.6255 mL
    40 mM 0.1388 mL 0.6938 mL 1.3877 mL 3.4691 mL
    50 mM 0.1110 mL 0.5551 mL 1.1101 mL 2.7753 mL
    H2O 60 mM 0.0925 mL 0.4626 mL 0.9251 mL 2.3128 mL
    80 mM 0.0694 mL 0.3469 mL 0.6938 mL 1.7346 mL
    100 mM 0.0555 mL 0.2775 mL 0.5551 mL 1.3877 mL

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    i-Inositol Related Classifications

    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    i-Inositol87-89-8myo-Inositol meso-InositolEndogenous Metabolitemyo-inositolOligo-astheno-teratozoospermia (OAT)SpermInhibitorinhibitorinhibit

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