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Results for "

Aflatoxin+B+1

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

2

Biochemical Assay Reagents

9

Natural
Products

1

Isotope-Labeled Compounds

1

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N6771
    Cyclopiazonic acid
    5+ Cited Publications

    		 Calcium Channel 5-HT Receptor MDM-2/p53 Apoptosis RSV Infection
    Cyclopiazonic acid is an endoplasmic reticulum calcium ATPase (ECAs) inhibitor and human respiratory syncytial virus (RSV) inhibitor (EC50 value of 4.13 μ M), which can reduce the antagonistic effect of 5-HT receptors in rat thoracic aorta, induce p53 dependent cell apoptosis and reproductive toxicity in mouse testes, and inhibit the biological activation of aflatoxin B [1][4][5].
    Cyclopiazonic acid
  • HY-W145667
    Mannan
    1 Publications Verification

    		 Endogenous Metabolite Glycosidase Bacterial Interleukin Related Reactive Oxygen Species (ROS) Infection Metabolic Disease Inflammation/Immunology
    Mannan is an orally active polysaccharide compound that binds to the mannose receptor (MR). Mannan promotes bacterial uptake and endosomal degradation by binding to MR, thereby enhancing the production of IL-12 in immune cells. Mannan enhances ROS production. Mannan modulates immunity, inhibits Aflatoxin B1 (HY-N6615)-induced toxicity, and reduces lipid [1] .
    Mannan
  • HY-119663
    Averantin

    		Fungal Infection
    Averantin is the minor metabolite of the fungus Cercospora arachidicola [1]. Averantin is an aflatoxin B1 precursor that can be used in the biosynthetic pathway .
    Averantin
  • HY-N6695
    Aflatoxicol

    Aflatoxin R0

    		 Drug Metabolite Cancer
    Aflatoxin (Aflatoxin R0) is a metabolite of aflatoxin B1 produced from Rhizopus spp [1], and is mutagenic and carcinogenic mycotoxin .
    Aflatoxicol
  • HY-W275553
    4-Decanol

    		DNA Alkylator/Crosslinker Infection
    4-Decanol is an antimutagenic compound, that can be isolated from mustard leaves. 4-Decanol inhibits mutagenic activities of Aflatoxin B1 (HY-N6615) and MNNG (HY-128612) in Salmonella typhimurium TA100 [1] .
    4-Decanol
  • HY-129247
    Versicolorin A

    		MDM-2/p53 Aryl Hydrocarbon Receptor Cytochrome P450 Cancer
    Versicolorin A is a biosynthetic precursor of Aflatoxin B1 (HY-N6615). Versicolorin A induces phosphorylation of p53. Versicolorin A activates the aryl hydrocarbon receptor AhR and significantly induces the expression of CYP1A1. Versicolorin A exerts genotoxic and cytotoxic effects. Versicolorin A enhances the genotoxicity of aflatoxin B1 in cells by promoting CYP450-mediated bioactivation of aflatoxin B1. Versicolorin A can be used in research related to colorectal cancer and hepatocellular carcinoma [1] .
    Versicolorin A
  • HY-N11845
    Sigmoidin B

    		Lipoxygenase Metabolic Disease Inflammation/Immunology
    Sigmoidin B, a prenylated flavanone, is a selective 5-lipoxygenase inhibitor. Sigmoidin B is a potent scavenger of the DPPH radical. Sigmoidin B has antigenotoxic activity that inhibits genotoxicity induced by Aflatoxin B1 (HY-N6615), with an IC50 of 18.7 μg/mL. Sigmoidin B has anti-inflammatory activity and antioxidant properties [1] .
    Sigmoidin B
  • HY-Y0790R
    Cuminaldehyde (Standard)

    p-Isopropylbenzaldehyde (Standard)

    		 α-synuclein Reference Standards Infection Neurological Disease Inflammation/Immunology Cancer
    Cuminaldehyde Standard is the analytical standard of Cuminaldehyde. This product is intended for research and analytical applications. Cuminaldehyde is the main component of Cuminum cyminum and has multiple biological activities, including anti-inflammatory, anti-cancer, anti-diabetic, anti-injury, anti-neuropathy and antibacterial effects. Cuminaldehyde is an inhibitor of aldose reductase (IC50= 0.00085 mg/mL) and α-glucosidase (IC50=0.5 mg/mL). Cuminaldehyde also inhibits the fibrillation of α-synuclein and prevents its aggregation Cuminaldehyde can induce apoptosis in colon adenocarcinoma cells by targeting topoisomerase I and II. In addition, Cuminaldehyde also exerts anti-inflammatory activity by inhibiting lipoxygenase. Cuminaldehyde has a strong inhibitory effect on the growth of Aspergillus flavus and the biosynthesis of aflatoxin B1 (AFB1). Cuminaldehyde can exert anti-injury and anti-neuropathy effects by participating in opioid receptors, L-arginine/NO/cGMP pathways and anti-inflammatory effects. Cuminaldehyde has potential application value in the research of neurodegenerative diseases, cancer, diabetes and neuropathic pain diseases [1] .
    Cuminaldehyde (Standard)
  • HY-158278A
    Aflatoxin B1/OVA

    		Biochemical Assay Reagents Inflammation/Immunology
    Aflatoxin B1/OVA is an antigen-adjuvant conjugate conjugate of Aflatoxin B1 (HY-N6615) and ovalbumin (OVA). By conjugating the antigen with a protein adjuvant, the production of antigen-specific antibodies in vaccine models can be enhanced. The conjugate does not affect protein folding or disrupt major epitopes, and can enhance cross-presentation and the production of antigen-specific T cells.
    Aflatoxin B1/OVA
  • HY-N15309
    Torvoside C

    Torvoside K

    		 Fungal Infection
    Torvoside C (Torvoside K) is a compound found in Solanum torvum with antifungal activity. The ZOIs and MIC values of Torvoside C against the tested fungi (Alternaria brassicicola, Alternaria geophila, Aspergillus flavus, etc.) range from 33.4% to 87.4% and 31.25 to 250 μg/mL, respectively. Additionally, it exhibits a dose-dependent inhibitory effect on the production of mycotoxins aflatoxin B1 and fumonisin B1, which are produced by A. flavus and F. verticillioides, respectively. Torvoside C can be used for research in the field of antifungal infection [1].
    Torvoside C
  • HY-W275553R
    4-Decanol (Standard)

    		DNA Alkylator/Crosslinker Reference Standards Infection
    4-Decanol (Standard) is the analytical standard of 4-Decanol (HY-W275553). This product is intended for research and analytical applications. 4-Decanol is an antimutagenic compound, that can be isolated from mustard leaves. 4-Decanol inhibits mutagenic activities of Aflatoxin B1 (HY-N6615) and MNNG (HY-128612) in Salmonella typhimurium TA100 [1] .
    4-Decanol (Standard)
  • HY-N6771S
    Cyclopiazonic acid-13C20

    		Isotope-Labeled Compounds Infection
    Cyclopiazonic acid- 13C20 is the 13C-labeled Cyclopiazonic acid (HY-N6771). Cyclopiazonic acid is an endoplasmic reticulum calcium ATPase (ECAs) inhibitor and human respiratory syncytial virus (RSV) inhibitor (EC50 value of 4.13 μ M), which can reduce the antagonistic effect of 5-HT receptors in rat thoracic aorta, induce p53 dependent cell apoptosis and reproductive toxicity in mouse testes, and inhibit the biological activation of aflatoxin B .
    Cyclopiazonic acid-13C20

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