AKR7A2 Antibody (YA7048)

Cat. No.: HY-P87365: Data Sheet User Guide for Antibodies
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AKR7A2 Antibody (YA7048) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to AKR7A2.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

AKR7A2 Antibody (YA7048) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to AKR7A2.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 40 kDa;

Observed band size: 40 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Zebrafish

SwissProt ID

O43488

Immunogen

Synthetic peptide within Human AKR7A2 aa 97-146 / 359.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-1:2000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:200

Sensitivity	Endogenous	Purity	Protein A affinity purified.
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). Has broad substrate specificity. Has NADPH-dependent aldehyde reductase activity towards 2-carboxybenzaldehyde, 2-nitrobenzaldehyde and pyridine-2-aldehyde (in vitro). Can reduce 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro). Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen

Subcellular Localization：Mitochondrion,Golgi apparatus,Cytoplasm

Expression：
Tissue_Specificity: Detected in brain, liver, small intestine and testis, and at lower levels in heart, prostate, skeletal muscle and spleen. Detected in kidney proximal and distal tubules, endothelial cells lining the Bowman's capsules and some cysts. Detected at low levels in lung and pancreas (at protein level). Widely expressed

Subunit：Homodimer

Synonyms

AFAR antibody; AFAR1 antibody; AFB1 aldehyde reductase 1 antibody; AFB1 AR1 antibody; AFB1-AR 1 antibody; AFB1AR1 antibody; Aflatoxin aldehyde reductase antibody; Aflatoxin B1 aldehyde reductase member 2 antibody; Aflatoxin beta1 aldehyde reductase antibody; Aiar antibody

Documentation

User Guide for Antibodies (1077 KB)