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antifungal+antibiotic

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Cat. No. 상품명 Target 연구분야 Chemical Structure
  • HY-N6782
    Oligomycin
    Maximum Cited Publications
    105 Publications Verification

    		 Oxidative Phosphorylation ATP Synthase Fungal Antibiotic Infection Cancer
    Oligomycin, an antifungal antibiotic, is an inhibitor of H +-ATP-synthase. Oligomycin blocks oxidative phosphorylation and the electron transport chain. Oligomycin inhibits HIF-1alpha expression in hypoxic tumor cells .
    Oligomycin
  • HY-N6716
    Filipin complex
    45+ Cited Publications

    		 Fungal Antibiotic Infection
    Filipin complex is a potent polyene macrolide antifungal antibiotic. Filipin complex inserts into membranes and sequester cholesterol into complexes and inhibits PRRSV entry. The Filipin complex consists of about 75.8% Filipin III (HY-N6718), 10.8% Filipin IV, 9.1% Filipin II, and 1.2% Filipin I (Ex/Em = 380/430 nm) .
    Filipin complex
  • HY-17409
    Nystatin
    50+ Cited Publications

    		 Fungal Antibiotic Apoptosis Bacterial Infection Cancer
    Nystatin is an orally active polyene antifungal antibiotic effective against yeast and mycoplasma. Nystatin increases the permeability of plasma membranes to small monovalent ions, including chloridion . Nystatin is a cholesterol-sequestering agent , partially prevents Oxaliplatin-induced lipid raft aggregation, DR4 and DR5 clustering, and thereby reduces apoptosis .
    Nystatin
  • HY-16909
    Leptomycin B
    20+ Cited Publications

    CI 940; LMB

    		 CRM1 Fungal Antibiotic Infection Cancer
    Leptomycin B (CI 940; LMB) is a potent inhibitor of the nuclear export of proteins. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue. Leptomycin B is a potent antifungal antibiotic blocking the eukaryotic cell cycle .
    Leptomycin B
  • HY-N6718
    Filipin III
    20+ Cited Publications

    		 Antibiotic Fungal Inflammation/Immunology
    Filipin III is the major component of Filipin, a 28-membered ring pentaene macrolide antifungal antibiotic produced by S. filipinensis, S. avermitilis and S. miharaensis. Filipin interacts with membrane sterols causing the alteration of membrane structure .
    Filipin III
  • HY-17583
    Griseofulvin
    1 Publications Verification

    		 Environmental Pollutants Antibiotic Apoptosis Fungal Endogenous Metabolite Bcl-2 Family Caspase Microtubule/Tubulin Infection Cardiovascular Disease Cancer
    Griseofulvin is an orally active antifungal antibiotic with antitumor activity. Griseofulvin induces apoptosis and G2/M cell cycle arrest in cancer cells. Griseofulvin also has cardiovascular modulatory activity, reducing angina pectoris, relieving hand artery spasm associated with onychomycosis, and peripheral vascular diseases such as shoulder-hand syndrome .
    Griseofulvin
  • HY-112177
    Myxothiazol

    		Fungal Mitochondrial Metabolism Antibiotic Infection
    Myxothiazol, an antifungal antibiotic, is a mitochondrial electron transport chain complex III (bc1 complex) inhibitor. Myxothiazol inhibits the growth of many yeasts and fungi at concentrations between 0.01 and 3 μg/ml .
    Myxothiazol
  • HY-108874
    Candicidin

    Levorin; Vanobid; Candimon

    		 Antibiotic Fungal Bacterial Infection
    Candicidin is a polyene antifungal antibiotic agent and can be isolated from Streptomyces griseus or Actinomyces levoris .
    Candicidin
  • HY-DY1017
    Filipin complex (solution)

    		Antibiotic Fungal Infection
    Filipin complex (solution) is a potent polyene macrolide antifungal antibiotic. Filipin complex inserts into membranes and sequester cholesterol into complexes and inhibits PRRSV entry. The Filipin complex consists of about 75.8% Filipin III (HY-N6718) , 10.8% Filipin IV, 9.1% Filipin II, and 1.2% Filipin I (Ex/Em = 380/430 nm) .
    Solvent and concentration: DMSO: 5 mg/mL
    Filipin complex (solution)
  • HY-119759A
    Lipoxamycin hemisulfate

    		Antibiotic Fungal Infection
    Lipoxamycin hemisulfate is an antifungal antibiotic and a potent serine palmitoyltransferase inhibitor with an IC50 of 21 nM .
    Lipoxamycin hemisulfate
  • HY-19965
    UK-2A

    Antibiotic UK 2A

    		 Antibiotic Fungal Infection
    UK-2A (Antibiotic UK 2A) is a potent antifungal antibiotic. UK-2A shows antifungal activity .
    UK-2A
  • HY-125723
    Echinocandin B

    SL 7810; A-30912 A

    		 Endogenous Metabolite Fungal Antibiotic Infection
    Echinocandin B (SL 7810) is a lipopeptide antifungal antibiotic. Echinocandin B is produced by Aspergillus nidulans. Echinocandin B inhibits β-1,3-glucan activity, thereby blocking the biosynthesis of fungal cell walls. Echinocandin B exhibits activity against a variety of Aspergillus species .
    Echinocandin B
  • HY-126559
    Ansatrienin A

    Mycotrienin I

    		 Antibiotic Fungal Infection
    Ansatrienin A is an antifungal antibiotic that can be isolated from Streptomyces collinus .
    Ansatrienin A
  • HY-N14216
    Polyoxin L

    		Antibiotic Fungal Infection
    Polyoxin L is a nucleoside antifungal antibiotic and has significant effects on rice sheath blight .
    Polyoxin L
  • HY-119759
    Lipoxamycin

    		Fungal Infection
    Lipoxamycin is an antifungal antibiotic and a potent serine palmitoyltransferase inhibitor with an IC50 of 21 nM .
    Lipoxamycin
  • HY-N15107
    Polyoxin M

    		Antibiotic Fungal Infection
    Polyoxin M is a nucleoside antifungal antibiotic and has significant effects on rice sheath blight .
    Polyoxin M
  • HY-N14212
    Polyoxin G

    		Antibiotic Fungal Infection
    Polyoxin G is a nucleoside antifungal antibiotic and has significant effects on rice sheath blight .
    Polyoxin G
  • HY-N14208
    Polyoxin E

    		Antibiotic Fungal Infection
    Polyoxin E is a nucleoside antifungal antibiotic and has significant effects on rice sheath blight .
    Polyoxin E
  • HY-N14213
    Polyoxin H

    		Antibiotic Fungal Infection
    Polyoxin H is a nucleoside antifungal antibiotic and has significant effects on rice sheath blight .
    Polyoxin H
  • HY-N14211
    Polyoxin F

    		Antibiotic Fungal Infection
    Polyoxin F is a nucleoside antifungal antibiotic and has significant effects on rice sheath blight .
    Polyoxin F
  • HY-W715444
    Mucidin

    		Antibiotic Fungal Mitochondrial Metabolism Infection
    Mucidin is an antifungal antibiotic that inhibits electron-transfer reactions in the cytochrome bc1 complex of the mitochondrial respiratory chain .
    Mucidin
  • HY-121780
    Aranorosin

    		Fungal Antibiotic Infection
    Aranorosin, a potent antifungal antibiotic, has been isolated from the culture filtrate and mycelium of a strain of Pseudoarachniotus roseus Kuehn .
    Aranorosin
  • HY-159666
    Nystatin A1

    		Antibiotic Fungal Infection
    Nystatin A1 is a polyene macrolide antifungal antibiotic that can be isolated from Streptomyces noursei. Nystatin A1 binds to ergosterol on the fungal cell membrane, increasing the permeability of the cell membrane and causing leakage of cell contents, thereby inhibiting the growth and reproduction of fungi .
    Nystatin A1
  • HY-N14888
    Phyllosinol

    		Antibiotic Fungal Infection
    Phyllosinol is an antifungal antibiotic .
    Phyllosinol
  • HY-123474
    PF-1163B

    		Fungal Antibiotic Infection
    PF-1163B is an antifungal antibiotic .
    PF-1163B
  • HY-N15064
    Pulvilloric acid

    		Antibiotic Fungal Infection
    Pulvilloric acid is an antifungal antibiotic found in Pen. pulvillorum 504 .
    Pulvilloric acid
  • HY-N15350
    Demethylblasticidin S

    		Fungal Antibiotic Infection
    Demethylblasticidin S is an antifungal antibiotic that can be synthesized by Streptomyces griseochromogenes .
    Demethylblasticidin S
  • HY-N14192
    Maltophilin

    		Antibiotic Fungal Infection
    Maltophilin is a broad-spectrum antifungal antibiotic that has no antibacterial effect against Gram-positive and Gram-negative bacteria .
    Maltophilin
  • HY-105267
    LY 121019

    		Fungal Antibiotic Infection
    LY 121019 is a semi-synthetic antifungal antibiotic with strong anticandida activity with MIC50 value of 0.625 μg/mL .
    LY 121019
  • HY-125358
    Dactylfungin B

    MK 2266 B

    		 Antibiotic Fungal Infection
    Dactylfungin B (MK 2266 B) is an antifungal antibiotic that is active against Candida pseudotropicalis and other fungi, with an MIC value at <10 μg/mL .
    Dactylfungin B
  • HY-N15184
    Benanomicin B

    Pradimicin C

    		 Bacterial Fungal Infection
    Benanomicin B (Pradimicin C) is an antifungal antibiotic that also has antibacterial activity against two Gram-positive bacteria: Micrococcus luteus and Corynebacterium bovis .
    Benanomicin B
  • HY-N14582
    Glomosporin

    		Antibiotic Fungal Infection
    Glomosporin is a cyclic ester peptide antifungal antibiotic, and it has moderate anti-Aspergillus flavus (including Aspergillus Niger and Aspergillus Niger), yeast activity (MIC is 16 μg/mL) .
    Glomosporin
  • HY-N13880
    Adustin

    		Antibiotic Fungal Infection
    Adustin, an antifungal antibiotic, is a polypeptide with translation-inhibiting activity. Adustin inhibits translation in a cell-free rabbit reticulocyte lysate system with an IC50 of 0.34 μM .
    Adustin
  • HY-N14269
    Ezomycin A2

    		Antibiotic Fungal Infection
    Ezomycin A2 is an antifungal antibiotic. Ezomycin A2 is mainly active against phytopathogens such as Sclerotinia sclerotiorum and Botrytis, and has a control effect on Sclerotinia, Botrytis and Candidiasis of crops .
    Ezomycin A2
  • HY-N14283
    Ezomycin D2

    		Antibiotic Fungal Infection
    Ezomycin D2 is an antifungal antibiotic. Ezomycin D2 is mainly active against phytopathogens such as Sclerotinia sclerotiorum and Botrytis, and has a control effect on Sclerotinia, Botrytis and Candidiasis of crops .
    Ezomycin D2
  • HY-152909
    Nystatin A2

    		Fungal Infection
    Nystatin A2 is an active component of antifungal agent, Nystatin (HY-17409). Nystatin is an orally active polyene antifungal antibiotic effective against yeast and mycoplasma .
    Nystatin A2
  • HY-W736195
    5-Hydroxy-4-oxo-L-norvaline

    		Antibiotic Bacterial Infection
    5-Hydroxy-4-oxo-L-norvaline is an antifungal antibiotic. 5-Hydroxy-4-oxo-L-norvaline can inhibit protein biosynthesis .
    5-Hydroxy-4-oxo-L-norvaline
  • HY-119759AR
    Lipoxamycin hemisulfate (Standard)

    		Antibiotic Reference Standards Fungal Infection
    Lipoxamycin (hemisulfate) (Standard) is the analytical standard of Lipoxamycin (hemisulfate). This product is intended for research and analytical applications. Lipoxamycin hemisulfate is an antifungal antibiotic and a potent serine palmitoyltransferase inhibitor with an IC50 of 21 nM[1][2].
    Lipoxamycin hemisulfate (Standard)
  • HY-N13154
    Malolactomycin C

    		Antibiotic Fungal Infection
    Malolactomycin C (compound 1) is a macrolide antifungal antibiotic isolated from Streptomyces strain KP-3144. Malolactomycin C is an effective inhibitor of Botrytis cinerea and thus controls a variety of plant diseases including gray mold .
    Malolactomycin C
  • HY-N14685
    Heptaibin

    		Antibiotic Fungal Infection
    Heptaibin is a peptaibol antifungal antibiotic. Heptaibin has the activity against Gram-positive bacteria (MIC is 8 μg/mL) such as Staphylococcus aureus and fungi (MIC is 13-32 μg/mL) such as Aspergillus, Candida albicans and cryptococcus neofordii, and it has moderate anti-Rhabditella pseudoelongata activity (MIC is 50 μg/mL) .
    Heptaibin
  • HY-N5160
    Arborcandin A

    		Antibiotic Fungal Infection
    Arborcandin A is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin A exhibits IC50 values of 0.25 μg/mL and 0.05 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin A has an MIC of 4-8 μg/mL against the genus Candida .
    Arborcandin A
  • HY-N5165
    Arborcandin F

    		Antibiotic Fungal Infection
    Arborcandin F is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin F exhibits IC50 values of 0.012 μg/mL against both Candida albicans and Aspergillus fumigatus. Additionally, Arborcandin F has an MIC of 2-4 μg/mL against the genus Candida .
    Arborcandin F
  • HY-N5163
    Arborcandin D

    		Antibiotic Fungal Infection
    Arborcandin D is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin D exhibits IC50 values of 3 μg/mL and 0.35 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin D has an MIC of 4 μg/mL against the genus Candida .
    Arborcandin D
  • HY-N5162
    Arborcandin C

    		Antibiotic Fungal Infection
    Arborcandin C is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin C exhibits IC50 values of 0.15 μg/mL and 0.015 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin C has an MIC of 1-2 μg/mL against the genus Candida .
    Arborcandin C
  • HY-N5161
    Arborcandin B

    		Antibiotic Fungal Infection
    Arborcandin B is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin B exhibits IC50 values of 0.30 μg/mL and 0.025 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin B has an MIC of 2-4 μg/mL against the genus Candida .
    Arborcandin B
  • HY-N5164
    Arborcandin E

    		Antibiotic Fungal Infection
    Arborcandin E is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin E exhibits IC50 values of 0.1 μg/mL and 0.012 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin E has an MIC of 0.5-2 μg/mL against the genus Candida .
    Arborcandin E
  • HY-129548
    Prumycin

    		Antibiotic Infection
    Prumycin is an antifungal antibiotic with activity against cucumber powdery mildew. Prumycin significantly inhibited the disease, whereas other metabolites such as bacillomycin D and surfactin did not. Prumycin did not induce the expression of plant defense genes, indicating that its effects were not through plant defense responses. Observation of cucumber cotyledons treated with prumycin showed that it could inhibit spore germination of P. fusca .
    Prumycin
  • HY-129548A
    Prumycin dihydrochloride

    		Fungal Infection
    Prumycin dihydrochloride is an antifungal antibiotic with activity against cucumber powdery mildew. Prumycin dihydrochloride significantly inhibited the disease, whereas other metabolites such as bacillomycin D and surfactin did not. Prumycin dihydrochloride did not induce the expression of plant defense genes, indicating that its effects were not through plant defense responses. Observation of cucumber cotyledons treated with prumycin showed that it could inhibit spore germination of P. fusca .
    Prumycin dihydrochloride
  • HY-117092
    BE-31405

    		Antibiotic Fungal Infection
    BE-31405 is an antifungal antibiotic. BE-31405 can be isolated from the culture broth of the fungal strains such as Penicillium minioluteum F31405, Talaromyces siamensis FKA-61, and Phomopsis sp. FKA-62. BE-31405 exhibits potent growth inhibitory activity against pathogenic fungal strains including Candida albicans, Candida glabrata, and Cryptococcus neoformans. BE-31405 shows no cytotoxicity against mammalian cells .
    BE-31405
  • HY-136926
    Candicidin A3

    FR-008I

    		 Fungal Infection
    Candicidin A3 (FR-008I) is an antifungal antibiotic with significant biological activity. Candicidin A3 can effectively inhibit the growth of fungi through its unique three-dimensional structure and seven-membered ring geometry. The absolute configuration of Candicidin A3 is a specific arrangement of multiple chiral centers, which may affect its biological activity and interaction with targets. Candicidin A3 can be used as a potential drug to inhibit fungal infections .
    Candicidin A3

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