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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
46 Results for "
enzymatic specificity
" in MedChemExpress (MCE) Product Catalog:
Products (46)
46 Results for "enzymatic specificity" in MCE Product Catalog:
6
Category:
Infection Natural Products Disease markers Metabolic Disease Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields
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5
5 Cited Publications
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VY-3-135 is a potent, orally active, and stable ACSS2 inhibitor with an IC50 value of 44 nM. VY-3-135 is specific to ACSS2 among the AcCoA synthetase family of enzymes. VY-3-135 does not inhibit ACSS1 or ACSS3 enzymatic activity. VY-3-135 can be used for the research of breast cancer .
5
4
4 Cited Publications
Synonyms: CC-90011 benzenesulfonate; LSD1-IN-7 benzenesulfonate
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Pulrodemstat (CC-90011) benzenesulfonate is a potent, selective, reversible and orally active inhibitor of lysine specific demethylase-1 (LSD1) with an IC50 of 0.25 nM. Pulrodemstat benzenesulfonate is less enzymatic inhibition against LSD2, MAO-A, and MAO-B. Pulrodemstat benzenesulfonate induces acute myeloid leukemia (AML) and small cell lung cancer (SCLC) cells differentiation and has potent anticancer activity .
4
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Pulrodemstat (CC-90011) is a potent, selective, reversible and orally active inhibitor of lysine specific demethylase-1 (LSD1) with an IC50 of 0.25 nM. Pulrodemstat is less enzymatic inhibition against LSD2, MAO-A, and MAO-B. Pulrodemstat induces acute myeloid leukemia (AML) and small cell lung cancer (SCLC) cells differentiation and has potent anticancer activity .
2
2 Cited Publications
Cat. No.: HY-P4931
CAS No.: 720710-69-0
2
2 Cited Publications
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PYZD-4409 is a specific inhibitor of the ubiquitin-activating enzyme UBA1 with an IC50 of 20 μM (cell-free enzymatic assay). PYZD-4409 induces cell death in malignant cells and preferentially inhibits the clonogenic growth of primary acute myeloid leukemia cells .
1
1 Cited Publications
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YG1702 is a potent ALDH18A1-specific inhibitor. YG1702 attenuates the growth of MYCN-amplified NB and down-regulates MYCN. YG1702 physically interacts with ALDH18A1 with a high affinity and might potentially affect its enzymatic activity .
1
1 Cited Publications
Cat. No.: HY-E70234B
Sortase A (MS grade) is a transpeptidase of Staphylococcus aureus, which can perform site-specific cleavage or transpeptidation linkage by utilizing the LPXTG recognition sequence. Sortase A (MS grade) can be utilized in high-sensitivity mass spectrometry (MS) applications and chemical enzymatic protein labeling.
Cat. No.: HY-B0504S2
Synonyms: NSC13123-d5
Cat. No.: HY-112624H
CAS No.: 9004-54-0
Synonyms: Dextran 2; Dextran D2; Dextran T2(MW 1600-2400)
Cat. No.: HY-P5990
CAS No.: 380225-52-5
Cat. No.: HY-131920A
CAS No.: 28086-43-3
Synonyms: Polyuridylic acid potassium
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Methyl β-D-glucopyranoside (Methyl β-D-glucoside) is a model glycosyl acceptor for enzymatic glycosylation reactions. Methyl β-D-glucopyranoside participates in glycoside synthesis and can react with acyl donors such as caffeic acid esters under the catalysis of specific enzymes (such as Lipozyme TL IM) to achieve acylation modification. Methyl β-D-glucopyranoside can generate biologically active derivatives (such as 6-O-caffeoyl glucoside). Methyl β-D-glucopyranoside can be used in organic synthesis and biocatalysis research, especially the efficient enzymatic preparation of medicinal glycosides (such as Robustaside B (HY-N2720), 6-O-caffeoyl salidroside) .
Cat. No.: HY-B0504S1
CAS No.: 1173022-95-1
Synonyms: NSC13123-13C
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INCB13739 is an orally active, potent, selective and tissue-specific11β-HSD1 (11β-hydroxysteroid dehydrogenase 1) inhibitor, with IC50 values of 3.2 nM (11β-HSD1 enzymatic) and 1.1 nM (11β-HSD1 PBMC), respectively. INCB13739 can be used for type 2 diabetes mellitus (T2DM) and obesity research .
Cat. No.: HY-134420
CAS No.: 10231-84-2
Synonyms: PNP α-L-Fuc
Cat. No.: HY-137421
CAS No.: 10139-02-3
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4-Nitrophenyl N-acetyl-α-D-glucosaminide is a 4-nitrophenyl- conjugated substrate for determining the enzymatic specificity .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
