DL-5-Indolylmethylhydantoin
Based on 1 Customer Validation
DL-5-Indolylmethylhydantoin can be used as a substrate for the enzymatic production of L-tryptophan in some specific bacteria.
For research use only. We do not sell to patients.
- Purity: 99.67%
- CAS No.: 21753-16-2
- Formula: C12H11N3O2
- Molecular Weight:229.23
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Jurkat | EC50 |
>10 μM
Compound: 54
|
Effective concentration required for inhibition of necroptosis in FADD deficient Jurkat T cells treated with TNF-alpha
Effective concentration required for inhibition of necroptosis in FADD deficient Jurkat T cells treated with TNF-alpha
|
[PMID: 16153840] |
Chemical Information
-
CAS No. 21753-16-2
-
Appearance Solid
-
Molecular Weight 229.23
-
Formula C12H11N3O2
-
Color White to off-white
-
SMILES
O=C1NC(C(CC2=CNC3=C2C=CC=C3)N1)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (436.24 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (272 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.3624 mL | 21.8122 mL | 43.6243 mL | 109.0608 mL |
| 5 mM | 0.8725 mL | 4.3624 mL | 8.7249 mL | 21.8122 mL | |
| 10 mM | 0.4362 mL | 2.1812 mL | 4.3624 mL | 10.9061 mL | |
| 15 mM | 0.2908 mL | 1.4541 mL | 2.9083 mL | 7.2707 mL | |
| 20 mM | 0.2181 mL | 1.0906 mL | 2.1812 mL | 5.4530 mL | |
| 25 mM | 0.1745 mL | 0.8725 mL | 1.7450 mL | 4.3624 mL | |
| 30 mM | 0.1454 mL | 0.7271 mL | 1.4541 mL | 3.6354 mL | |
| 40 mM | 0.1091 mL | 0.5453 mL | 1.0906 mL | 2.7265 mL | |
| 50 mM | 0.0872 mL | 0.4362 mL | 0.8725 mL | 2.1812 mL | |
| 60 mM | 0.0727 mL | 0.3635 mL | 0.7271 mL | 1.8177 mL | |
| 80 mM | 0.0545 mL | 0.2727 mL | 0.5453 mL | 1.3633 mL | |
| 100 mM | 0.0436 mL | 0.2181 mL | 0.4362 mL | 1.0906 mL |