Poly(U) potassium
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Polyuridylic acid potassium is a polynucleotide. In protein synthesis systems based on active mammalian ribosomes, Polyuridylic acid potassium acts as a specific messenger to induce the biosynthesis of polyphenylalanine, with no effect on the incorporation of non-phenylalanine amino acids. Polyuridylic acid potassium serves as a template to promote the non-enzymatic synthesis of oligoadenylates.
For research use only. We do not sell to patients.
- Purity: 99.9%
- CAS No.: 28086-43-3
- Formula: (C9H12KN2O9P)x
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All DNA/RNA Synthesis Isoforms
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Biological Activity
Polyuridylic acid potassium acts as a template to promote the non-enzymatic synthesis of oligoadenylates[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 28086-43-3
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Appearance Solid
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Formula (C9H12KN2O9P)x
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Color White to off-white
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SMILES
O=C(C=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(O)(O[K])=O)O2)NC1=O.[n]
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Synonyms
Polyuridylic acid potassium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
H2O : 100 mg/mL (Need ultrasonic)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. ARNSTEIN HR, et al. Function of polyuridylic acid and ribonucleic acid in protein biosynthesis by ribosomes from mammalian reticulocytes. Nature. 1962 Jun 16;194:1042-4. [Content Brief]
[2]. Sulston J, et al. Nonenzymatic synthesis of oligoadenylates on a polyuridylic acid template. Proc Natl Acad Sci U S A. 1968 Mar;59(3):726-33. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Poly(U) potassium Related Classifications
Cat. No.: HY-131920A
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- Poly(U)
- 28086-43-3
- Polyuridylic acid
- DNA/RNA Synthesis
- mammalian cell-free protein synthesis systems
- adenosine residues
- oligoadenylate chain initiation
- oligoadenylate chain extension
- phenylalanine
- internucleotide bond formation
- rabbit reticulocyte ribosomes
- polyphenylalanine biosynthesis
- mammalian ribosome-based protein synthesis systems
- adenosine-5'-phosphate
- Inhibitor
- inhibitor
- inhibit