28086-43-3
28086-43-3
Chemical Structure
Poly(U) potassium
Synonym(s): Polyuridylic acid potassium
- CAS No.: 28086-43-3
- Formula:(C9H12KN2O9P)x
- Molecular Weight:N/A
SMILES: O=C(C=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(O)(O[K])=O)O2)NC1=O.[n]
Biological Activity: Polyuridylic acid potassium is a polynucleotide. In protein synthesis systems based on active mammalian ribosomes, Polyuridylic acid potassium acts as a specific messenger to induce the biosynthesis of polyphenylalanine, with no effect on the incorporation of non-phenylalanine amino acids. Polyuridylic acid potassium serves as a template to promote the non-enzymatic synthesis of oligoadenylates[1][2].
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Poly(U) potassium | 99.9% | Polyuridylic acid potassium is a polynucleotide. In protein synthesis systems based on active mammalian ribosomes, Polyuridylic acid potassium acts as a specific messenger to induce the biosynthesis of polyphenylalanine, with no effect on the incorporation of non-phenylalanine amino acids. Polyuridylic acid potassium serves as a template to promote the non-enzymatic synthesis of oligoadenylates. | ||||||||||||||||||||
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References
- [1]. ARNSTEIN HR, et al. Function of polyuridylic acid and ribonucleic acid in protein biosynthesis by ribosomes from mammalian reticulocytes. Nature. 1962 Jun 16;194:1042-4. [Content Brief]
- [2]. Sulston J, et al. Nonenzymatic synthesis of oligoadenylates on a polyuridylic acid template. Proc Natl Acad Sci U S A. 1968 Mar;59(3):726-33. [Content Brief]
