Dextran T2 (MW 2,000)
Based on 1 Customer Validation
Dextran T2 (Dextran 2; Dextran T2(MW 1600-2400)) is a natural high molecular weight polysaccharide, the glycosidic bonds in its structure can be recognized by endo-dextranase and exo-dextranase. Dextran T2 (MW 2,000) breaks the glycosidic bonds in the enzymatic hydrolysis mechanism, releasing products such as D-glucose, Isomaltose (IM2), and Isomaltotriose (IM3). Dextran T2 (MW 2,000) can be used as a model substrate to characterize the catalytic properties of dextranase (such as optimal pH, temperature and product specificity), and to study enzymatic mechanism research and polysaccharide degradation pathways in glycobiology. The Dextran series of compounds are also a natural polysaccharide drug carrier, which can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong drug half-life, increase local concentration and reduce immune clearance activity.
For research use only. We do not sell to patients.
- CAS No.: 9004-54-0
- Formula: (C6H10O5)n
- Molecular Weight:1600-2400
-
Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
Biological Activity
Dextran T2 (MW 2,000) (1%; 60 min) is degraded into D-glucose (55%), isomaltose (IM2), and isomaltotriose (IM3) in a recombinant yeast cytoplasmic extract enzymatic digestion experiment[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 9004-54-0
-
Appearance Solid
-
Molecular Weight 1600-2400
-
Formula (C6H10O5)n
-
Color White to off-white
-
SMILES
[Dextran T2 (MW 2,000)]
-
Synonyms
Dextran 2; Dextran D2; Dextran T2(MW 1600-2400)
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
H2O : ≥ 100 mg/mL
* "≥" means soluble, but saturation unknown.
Purity & Documentation
-
Data Sheet (269 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
[1]. Chen F, et al. Preparation and application of dextran and its derivatives as carriers. Int J Biol Macromol. 2020 Feb 15;145:827-834. [Content Brief]
[2]. Cserr HF, et al. Bulk flow of interstitial fluid after intracranial injection of blue dextran 2000. Exp Neurol. 1974 Oct;45(1):50-60. [Content Brief]
[3]. Khalikova E, et al. Microbial dextran-hydrolyzing enzymes: fundamentals and applications. Microbiol Mol Biol Rev. 2005 Jun;69(2):306-25. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)